Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ramon K. Kemp"'
Autor:
Ramon K. Kemp, Marian Iwamoto, Joshua Chen, Steven D. Young, Hedy Teppler, Robert A. Fromtling, Randi Y. Leavitt, Wei Xu, Robin Isaacs, Michael D. Miller, Daria J. Hazuda, Joseph P. Vacca, Bach-Yen Nguyen, Keith Gottesdiener, Michael W. Lower, Larissa Wenning, Michael Rowley, Peter Sklar
Publikováno v:
Annals of the New York Academy of Sciences. 1222:83-89
Raltegravir is the first integrase strand transfer inhibitor approved for the treatment of HIV-1 infection. As the first agent in this new class of antiretroviral therapies, raltegravir has demonstrated safety and efficacy in treatment-naive as well
Autor:
Ian Taylor, Charlotte M. Keenan, Shyamal D. Peddada, Stephen P. Schmidt, Roy L. Kerlin, Matthias Rinke, John M. Pletcher, Douglas C. Wolf, Susan A. Elmore, Ramon K. Kemp, Sabine Francke-Carroll
Publikováno v:
Toxicologic Pathology. 37:679-693
CHARLOTTE KEENAN, SUSAN ELMORE, SABINE FRANCKE-CARROLL, RAMON KEMP, ROY KERLIN, SHYAMAL PEDDADA, JOHN PLETCHER, MATTHIAS RINKE, STEPHEN PETER SCHMIDT, IAN TAYLOR, AND DOUGLAS C. WOLF GlaxoSmithKline, King of Prussia, Pennsylvania, USA National Toxico
Publikováno v:
Pharmacology & Toxicology. 88:45-50
The experimental class III antiarrhythmic drug, L-768673, prolongs the refractory period of cardiac myocytes by selectively blocking the slow-activating delayed rectifying potassium (I Ks ) channel. The I Ks channel has also been identified in vestib
Autor:
Victor D.-H. Ding, H.M. Saunders, Linda Rhodes, Atif M. Nakhla, Bill Pikounis, M S Khan, William Rosner, Ramon K. Kemp, William P. Feeney
Publikováno v:
The Prostate. 44:8-18
BACKGROUND Previous studies have shown that chronic treatment of castrate dogs with androgen and estrogen results in significant prostate growth. Estrogen treatment of castrate dogs in the absence of androgen has resulted in conflicting data as repor
Autor:
Noel Dybdal, Xavier Fouillet, Rick Perry, Darrell L. Tuomari, Rani S. Sellers, Ramon K. Kemp, John T. Yarrington, Frank J. Geoly
Publikováno v:
Toxicologic pathology. 35(3)
The Society of Toxicologic Pathology (STP) has developed the following recommendations for the use of pathology images in compliance with the Code of Federal Regulations (CFR), Volume 21, Part 58 (Good Laboratory Practices [GLP]) and Part 11 (Electro
Autor:
Mrinal M. Patnaik, Ramon K. Kemp, Mark D. Minden, Amy Meister, Clayton D. Knox, Ivana Gojo, Raoul Tibes, Hagop M. Kantarjian, Mary Elizabeth Jones, Shelonitda Rose, Amy O. Johnson Levonas, Farhad Ravandi, Raymond L. H. Lam, Payal Shah Patel, Craig Fancourt
Publikováno v:
Journal of Clinical Oncology. 33:7070-7070
7070 Background: Human double minute 2 (HDM2) binds to and inhibits wild-type (WT) p53, thereby promoting oncogenesis. MK-8242 is a potent, orally bioavailable, small-molecule inhibitor of the HDM2...
Autor:
Ramon K. Kemp, Richard Perry, Ken Schafer, Jeffrey McCartney, Thomas M. Monticello, Daniel Morton, Nigel Roome, Olga Pulido, Rani S. Sellers, Karl F. Jensen, Sabine Francke-Carroll, Paul W. Snyder
Publikováno v:
Toxicologic pathology. 34(6)
Pfizer, Inc., Groton, Connecticut 06340, USA Merck Research Laboratories, West Point, Pennsylvania 19586 USA Pathology Branch, Center for Food Safety and Applied Nutrition, FDA, College Park, Maryland 20740, USA U.S. Environmental Protection Agency,