Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ramon Guerra de Oliveira"'
Publikováno v:
Química Nova, Vol 45, Iss 7, Pp 831-846 (2022)
Artemisinin, a natural sesquiterpene isolated from the Artemisia annua L. plant, represents a remarkable achievement in the treatment against malaria. Since its discovery in the 1970’s, researchers readily started synthesizing this complex natural
Externí odkaz:
https://doaj.org/article/29e82d472d4444f0aa959c6189011949
Autor:
Ramon Guerra de Oliveira, Fabiana Sélos Guerra, Cláudia dos Santos Mermelstein, Patrícia Dias Fernandes, Isadora Tairinne de Sena Bastos, Fanny Nascimento Costa, Regina Cely Rodrigues Barroso, Fabio Furlan Ferreira, Carlos Alberto Manssour Fraga
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1181-1193 (2018)
In this study, we synthesized a new congener series of N-sulphonylhydrazones designed as candidate ROCK inhibitors using the molecular hybridization of the clinically approved drug fasudil (1) and the IKK-β inhibitor LASSBio-1524 (2). Among the synt
Externí odkaz:
https://doaj.org/article/d73b148125364d7da3c2636102c54a57
Autor:
Francisco José Seixas Xavier, Klinger Antonio da Franca Rodrigues, Ramon Guerra de Oliveira, Claudio Gabriel Lima Junior, Juliana da Câmara Rocha, Tatjana Souza Lima Keesen, Marcia Rosa de Oliveira, Fábio Pedrosa Lins Silva, Mário Luiz Araújo de Almeida Vasconcellos
Publikováno v:
Molecules, Vol 21, Iss 11, p 1483 (2016)
Leishmaniasis represents a series of severe neglected tropical diseases caused by protozoa of the genus Leishmania and is widely distributed around the world. Here, we present the syntheses of Morita-Baylis-Hillman adducts (MBHAs) prepared from eugen
Externí odkaz:
https://doaj.org/article/d42a07c9888f475dbefc599e861c0458
Autor:
Patricia Dias Fernandes, Carlos A. M. Fraga, Regina C. Barroso, Ramon Guerra de Oliveira, Fanny N. Costa, Claudia Mermelstein, Fabiana Sélos Guerra, Isadora T.S. Bastos, Fabio Furlan Ferreira
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1181-1193 (2018)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
In this study, we synthesized a new congener series of N-sulphonylhydrazones designed as candidate ROCK inhibitors using the molecular hybridization of the clinically approved drug fasudil (1) and the IKK-β inhibitor LASSBio-1524 (2). Among the synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f185f8a269880270bdcb5d355fb59a07
https://doaj.org/article/d73b148125364d7da3c2636102c54a57
https://doaj.org/article/d73b148125364d7da3c2636102c54a57
Autor:
Ramon Guerra de Oliveira, Carlos A. M. Fraga, Patricia Dias Fernandes, Fabiana Sélos Guerra, Claudia Mermelstein
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports
Scientific Reports
Tumor aggressiveness is usually associated with metastasis. MDA-MB 231, a triple-negative breast cancer (TNBC), is an aggressive type of breast cancer and associated with early metastasis. The Rho/ROCK pathway is a key regulator of cell motility invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e725e953056434ec59f0f16b482958
http://link.springer.com/article/10.1038/s41598-017-14216-z
http://link.springer.com/article/10.1038/s41598-017-14216-z
Autor:
Ramon Guerra de Oliveira, Carlos A. M. Fraga, Claudia Mermelstein, Fabiana Sélos Guerra, Patricia Dias Fernandes
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::647007e2bd49e2e56e885b1e2fdcc814
https://doi.org/10.1096/fasebj.2018.32.1_supplement.836.7
https://doi.org/10.1096/fasebj.2018.32.1_supplement.836.7