Zobrazeno 1 - 10
of 465
pro vyhledávání: '"Ramon Eritja"'
Autor:
Luis M. Menéndez-Méndez, Carme Fàbrega, Anna Aviñó, Ramon Eritja, Yoon-Sik Lee, Yogesh S. Sanghvi, Susana Fernández, Miguel Ferrero
Publikováno v:
Results in Chemistry, Vol 12, Iss , Pp 101930- (2024)
A critical step in the manufacturing of oligonucleotides is the selection of ideal solid supports. Herein, we evaluate a hybrid core–shell solid support made of polystyrene and polyethyleneglycol, for the preparation of oligonucleotides using phosp
Externí odkaz:
https://doaj.org/article/5d46ba76923f474c957e8a91dcfa08de
Autor:
Virginia Martín-Nieves, Luis Miguel Menéndez-Méndez, Carme Fàbrega, Susana Fernández, Yogesh S. Sanghvi, Miguel Ferrero, Ramon Eritja
Publikováno v:
ACS Omega, Vol 8, Iss 47, Pp 44893-44904 (2023)
Externí odkaz:
https://doaj.org/article/b7a56be495fe4d44af169a1bde2d8f4c
Autor:
Carme Fàbrega, Núria Gallisà-Suñé, Alice Zuin, Juan Sebastián Ruíz, Bernat Coll-Martínez, Gemma Fabriàs, Ramon Eritja, Bernat Crosas
Publikováno v:
Cells, Vol 13, Iss 21, p 1767 (2024)
The development of novel tools to tackle viral processes has become a central focus in global health, during the COVID-19 pandemic. The spike protein is currently one of the main SARS-CoV-2 targets, owing to its key roles in infectivity and virion fo
Externí odkaz:
https://doaj.org/article/00d1b154c83841d2a3310f94588a1da2
Autor:
Stefania Mazzini, Gigliola Borgonovo, Salvatore Princiotto, Roberto Artali, Loana Musso, Anna Aviñó, Ramon Eritja, Raimundo Gargallo, Sabrina Dallavalle
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0306239 (2024)
Quadruplex-Duplex (Q-D) junctions are unique structural motifs garnering increasing interest as drug targets, due to their frequent occurrence in genomic sequences. The viral HIV LTR-III sequence was chosen as a Q-D junction model to study the affini
Externí odkaz:
https://doaj.org/article/2331e4309b364e6eae6e62f9e04df694
Publikováno v:
Molecules, Vol 28, Iss 21, p 7278 (2023)
This Special issue is dedicated to the memory of Enrique Pedroso, Professor Emeritus of Organic Chemistry at University of Barcelona, who passed away at the age of 72 in September 2020 [...]
Externí odkaz:
https://doaj.org/article/09f045c9101d4956a8ff5e03e57e0471
Autor:
Jordi Guiteras, Élia Ripoll, Núria Bolaños, Laura De Ramon, Pere Fontova, Núria Lloberas, Josep Maria Cruzado, Josep Maria Aràn, Anna Aviñó, Ramon Eritja, Montse Gomà, Rosario Taco, Josep Maria Grinyó, Juan Torras
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss , Pp 807-821 (2021)
Systemic lupus erythematosus is a highly complex and heterogeneous autoimmune disease mostly mediated by B cells. It is characterized by circulating self-reactive antibodies that deposit and form immune complexes in kidney, leading to irreparable tis
Externí odkaz:
https://doaj.org/article/74ac3e61a22d442ebac7639caa26d250
Autor:
Sabrina Dallavalle, Loana Musso, Roberto Artali, Anna Aviñó, Leonardo Scaglioni, Ramon Eritja, Raimundo Gargallo, Stefania Mazzini
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Poly ADP-ribose polymerases (PARP) are key proteins involved in DNA repair, maintenance as well as regulation of programmed cell death. For this reason they are important therapeutic targets for cancer treatment. Recent studies have revealed
Externí odkaz:
https://doaj.org/article/f7228d4c577546f6824be235df0c9bc6
Autor:
Carme Fàbrega, Anna Aviñó, Natalia Navarro, Andreia F. Jorge, Santiago Grijalvo, Ramon Eritja
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 320 (2023)
Antisense and small interfering RNA (siRNA) oligonucleotides have been recognized as powerful therapeutic compounds for targeting mRNAs and inducing their degradation. However, a major obstacle is that unmodified oligonucleotides are not readily take
Externí odkaz:
https://doaj.org/article/1c74d3f8abe840a29b0c5a7bb3845dec
Autor:
Anna Clua, Santiago Grijalvo, Namrata Erande, Swati Gupta, Kristina Yucius, Raimundo Gargallo, Stefania Mazzini, Muthiah Manoharan, Ramon Eritja
Publikováno v:
Molecules, Vol 28, Iss 1, p 98 (2022)
In the original article [...]
Externí odkaz:
https://doaj.org/article/ef2f3b19912d4853b58816d326fa8754
Autor:
Dr. Anna Aviñó, Dr. Ugutz Unzueta, Dr. María Virtudes Céspedes, Dr. Isolda Casanova, Dr. Esther Vázquez, Prof. Dr. Antonio Villaverde, Prof. Dr. Ramon Mangues, Prof. Dr. Ramon Eritja
Publikováno v:
ChemistryOpen, Vol 8, Iss 3, Pp 382-387 (2019)
Abstract Oligonucleotide‐protein conjugates have important applications in biomedicine. Simple and efficient methods are described for the preparation of these conjugates. Specifically, we describe a new method in which a bifunctional linker is att
Externí odkaz:
https://doaj.org/article/25c070b1a7f94a76865eefb775eb2f2a