Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ramoji Kosuru"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/b75db3c8b115418f93936d1392e71752
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 9853 (2024)
The vascular endothelium, a specialized monolayer of endothelial cells (ECs), is crucial for maintaining vascular homeostasis by controlling the passage of substances and cells. In the tumor microenvironment, Vascular Endothelial Growth Factor A (VEG
Externí odkaz:
https://doaj.org/article/db09b48456a84e5482cf60d2e80c6fff
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/6d48cbc4624f468d9a0298fa00b9a3f2
Autor:
Ramoji Kosuru, Bandana Singh, Sribalaji Lakshmikanthan, Yoshinori Nishijima, Jeannette Vasquez-Vivar, David X. Zhang, Magdalena Chrzanowska
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/ee84f766144340ba8328ab625c967ff5
Autor:
Ramoji Kosuru, Bandana Singh, Sribalaji Lakshmikanthan, Yoshinori Nishijima, Jeannette Vasquez-Vivar, David X. Zhang, Magdalena Chrzanowska
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Small GTPase Rap1 plays a prominent role in endothelial cell (EC) homeostasis by promoting NO release. Endothelial deletion of the two highly homologous Rap1 isoforms, Rap1A and Rap1B, leads to endothelial dysfunction ex vivo and hypertension in vivo
Externí odkaz:
https://doaj.org/article/727ec66ccc314234a4f972f3a20f24c6
Autor:
Ramoji Kosuru, Yin Cai, Vidya Kandula, Dan Yan, Chunyan Wang, Hong Zheng, Yalan Li, Michael G. Irwin, Sanjay Singh, Zhengyuan Xia
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 4, Pp 1381-1397 (2018)
Background/Aims: Pterostilbene (PT) exerts antidiabetic effects by decreasing blood glucose and modulating lipid metabolism and has been shown to attenuate myocardial ischemia-reperfusion (IR) injury in non-diabetic subjects. However, whether PT can
Externí odkaz:
https://doaj.org/article/0fecab51b9294b08a4cd2177c4187e16
Autor:
Ramoji Kosuru, Magdalena Chrzanowska
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1616 (2020)
Ca2+ is a universal intracellular signal. The modulation of cytoplasmic Ca2+ concentration regulates a plethora of cellular processes, such as: synaptic plasticity, neuronal survival, chemotaxis of immune cells, platelet aggregation, vasodilation, an
Externí odkaz:
https://doaj.org/article/8c945401dfe242e6b62d96fcf102ec17
Autor:
Ramoji Kosuru, Magdalena Chrzanowska, Yao Chen, Shikan Zheng, Robert Burns, Gang Xin, Sribalaji Lakshmikanthan, Guru Prasad Sharma, Weiguo Cui
Publikováno v:
Angiogenesis. 26:265-278
Overcoming vascular immunosuppression: lack of endothelial cell (EC) responsiveness to inflammatory stimuli in the proangiogenic environment of tumors, is essential for successful cancer immunotherapy. The mechanisms through which Vascular Endothelia
Autor:
Nirupama Kandula, Saurabh Kumar, Venkata Kiran Kumar Mandlem, Aneela Siddabathuni, Sanjay Singh, Ramoji Kosuru
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-18
Recent studies indicate cell death is the hallmark of cardiac pathology in myocardial infarction and diabetes. The AMP-activated protein kinase (AMPK) signalling pathway is considered a putative salvaging phenomenon, plays a decisive role in almost a
Publikováno v:
International Journal of Applied Pharmaceutics. :318-330
Objective: The present research aims to design, develop, optimize, characterize and evaluate dasatinib (DSB) loaded polymeric nanocarriers to treat chronic myeloid leukaemia (CML) by adopting a quality by design (QbD) approach. Methods: Risk assessme