A role for NPY-NPY2R signaling in albuminuric kidney disease

Autor: Lay, Abigail C., Barrington, A. Fern, Hurcombe, Jenny A., Ramnath, Raina D., Graham, Mark, Lewis, Philip A., Wilson, Marieangela C., Heesom, Kate J., Butler, Matthew J., Perrett, Rebecca M., Neal, Chris R., Herbert, Eleanor, Mountjoy, Edward, Atan, Denize, Nair, Viji, Ju, Wenjun, Nelson, Robert G., Kretzler, Matthias, Satchell, Simon C., McArdle, Craig A., Welsh, Gavin I., Coward, Richard J. M.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jul 01. 117(27), 15862-15873.

Externí odkaz: https://www.jstor.org/stable/26935153

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Response to There is little evidence that the endothelial glycocalyx has a specific role in glomerular permeability of albumin

Autor: Ramnath, Raina D, Butler, Matthew N, Foster, R R, Satchell, Simon C

Publikováno v: Ramnath, R D, Butler, M N, Foster, R R & Satchell, S C 2020, ' Response to There is little evidence that the endothelial glycocalyx has a specific role in glomerular permeability of albumin ', Kidney International, vol. 97, no. 5, pp. 1057–1058 . https://doi.org/10.1016/j.kint.2020.02.006

We write in response to the letter entitled “There is little evidence that the endothelial glycocalyx has a specific role in glomerular permeability of albumin,”1 in reference to our original publication.2 The letter title is very misleading. It

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2642::0222f414d2cd700f837862790c5213f9
https://hdl.handle.net/1983/7aa800d7-e5d3-41ec-97e8-be48a5268afa

Blocking matrix metalloproteinase-mediated syndecan-4 shedding restores the endothelial glycocalyx and glomerular filtration barrier function in early diabetic kidney disease:Syndecan 4 in diabetic kidney disease

Autor: Ramnath, Raina D, Butler, Matthew J, Newman, Georgina, Desideri, Sara, Russell, Amy, Lay, Abigail C, Neal, Chris R, Qiu, Yan, Fawaz, Sarah, Onions, Karen L, Gamez, Monica, Crompton, Michael, Michie, Chris, Finch, Natalie, Coward, Richard J, Welsh, Gavin I, Foster, Rebecca R, Satchell, Simon C

Publikováno v: Ramnath, R D, Butler, M J, Newman, G, Desideri, S, Russell, A, Lay, A C, Neal, C R, Qiu, Y, Fawaz, S, Onions, K L, Gamez, M, Crompton, M, Michie, C, Finch, N, Coward, R J, Welsh, G I, Foster, R R & Satchell, S C 2019, ' Blocking matrix metalloproteinase-mediated syndecan-4 shedding restores the endothelial glycocalyx and glomerular filtration barrier function in early diabetic kidney disease : Syndecan 4 in diabetic kidney disease ', Kidney International . https://doi.org/10.1016/j.kint.2019.09.035

The endothelial glycocalyx is a key component of the glomerular filtration barrier. We have shown that matrix metalloproteinase (MMP)-mediated syndecan 4 shedding is a mechanism of glomerular endothelial glycocalyx damage in vitro, resulting in incre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2642::b5640fe83004c7029c51492b1f6b4d24
https://research-information.bris.ac.uk/ws/files/225395820/PIIS008525381931110X.pdf

Reactive Oxygen Species Modulate the Barrier Function of the Human Glomerular Endothelial Glycocalyx.

Autor: Singh, Anurag^1,2 anuragsing@hotmail.com, Ramnath, Raina D.¹, Foster, Rebecca R.¹, Wylie, Emma C.¹, Fridén, Vincent³, Dasgupta, Ishita¹, Haraldsson, Borje³, Welsh, Gavin I.¹, Mathieson, Peter W.¹, Satchell, Simon C.¹

Publikováno v: PLoS ONE. Feb2013, Vol. 8 Issue 2, p1-8. 8p.