Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Rammohan Shukla"'
Autor:
Jennifer Nguyen, Melissa A. Curtis, Ali S. Imami, William G. Ryan, Khaled Alganem, Kari L. Neifer, Nilanjana Saferin, Charlotte N. Nawor, Brian P. Kistler, Gary W. Miller, Rammohan Shukla, Robert E. McCullumsmith
Publikováno v:
Translation, Vol 12, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/19421693822744e0944eb21064314f3a
Publikováno v:
Translation, Vol 11, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/0e21e978c9024a5992c163431153df1c
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S798-S799 (2023)
Externí odkaz:
https://doaj.org/article/6ed0014f3772432fa8d0e250d63a238c
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2815 (2024)
Several types of mood disorders lie along a continuum, with nebulous boundaries between them. Understanding the mechanisms that contribute to mood disorder complexity is critical for effective treatment. However, present treatments are largely center
Externí odkaz:
https://doaj.org/article/2ad2268548ec4e4c8a31fd7c46aee350
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionSynapses and spines play a significant role in major depressive disorder (MDD) pathophysiology, recently highlighted by the rapid antidepressant effect of ketamine and psilocybin. According to the Bayesian brain and interoception perspect
Externí odkaz:
https://doaj.org/article/ebb094a3bc7947dfb4ba6e18de0babe4
Autor:
Nicholas D. Henkel, Marissa A. Smail, Xiaojun Wu, Heather A. Enright, Nicholas O. Fischer, Hunter M. Eby, Robert E. McCullumsmith, Rammohan Shukla
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Animal models have expanded our understanding of temporal lobe epilepsy (TLE). However, translating these to cell-specific druggable hypotheses is not explored. Herein, we conducted an integrative insilico-analysis of an available transcript
Externí odkaz:
https://doaj.org/article/96f33045d9774ed79f416b8982c1c3dd
Autor:
Xiaolu Zhang, Alyssa Wolfinger, Xiaojun Wu, Rawan Alnafisah, Ali Imami, Abdul-rizaq Hamoud, Anna Lundh, Vladimir Parpura, Robert E. McCullumsmith, Rammohan Shukla, Sinead M. O’Donovan
Publikováno v:
Cells, Vol 11, Iss 20, p 3315 (2022)
Astrocytes have many important functions in the brain, but their roles in psychiatric disorders and their responses to psychotropic medications are still being elucidated. Here, we used gene enrichment analysis to assess the relationships between dif
Externí odkaz:
https://doaj.org/article/32c40c538ad443aca32d1f9207a02e20
Autor:
Justin F. Creeden, Khaled Alganem, Ali S. Imami, F. Charles Brunicardi, Shi-He Liu, Rammohan Shukla, Tushar Tomar, Faris Naji, Robert E. McCullumsmith
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8679 (2020)
Pancreatic cancer remains one of the most difficult malignancies to treat. Minimal improvements in patient outcomes and persistently abysmal patient survival rates underscore the great need for new treatment strategies. Currently, there is intense in
Externí odkaz:
https://doaj.org/article/1913e2c584794d5299f985afd4a8da6e
Autor:
Justin F. Creeden, Khaled Alganem, Ali S. Imami, Nicholas D. Henkel, F. Charles Brunicardi, Shi-He Liu, Rammohan Shukla, Tushar Tomar, Faris Naji, Robert E. McCullumsmith
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8823 (2020)
Kinase drug discovery represents an active area of therapeutic research, with previous pharmaceutical success improving patient outcomes across a wide variety of human diseases. In pancreatic ductal adenocarcinoma (PDAC), innovative pharmaceutical st
Externí odkaz:
https://doaj.org/article/47fdf85141cc4e3ea70b13f955d92f31
Autor:
Xiaolu Zhang, Mahmoud Ali Eladawi, William George Ryan, Xiaoming Fan, Stephen Prevoznik, Trupti Devale, Barkha Ramnani, Krishnamurthy Malathi, Etienne Sibille, Robert Mccullumsmith, Toshifumi Tomoda, Rammohan Shukla
The underlying biological mechanisms that contribute to the heterogeneity of major depressive disorder (MDD) presentation remain poorly understood, highlighting the need for a conceptual framework that can explain this variability and bridge the gap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c08b5ff1661c7d9496f65b24c5ea1d6
https://doi.org/10.1101/2023.05.04.539419
https://doi.org/10.1101/2023.05.04.539419