Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Rammohan Shukla"'
Autor:
Abdul-rizaq Hamoud, Khaled Alganem, Sean Hanna, Michael Morran, Nicholas Henkel, Ali S. Imami, William Ryan, Smita Sahay, Priyanka Pulvender, Austin Kunch, Taylen O. Arvay, Jarek Meller, Rammohan Shukla, Sinead M. O’Donovan, Robert McCullumsmith
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Protein kinases are critical components of a myriad biological processes and strongly associated with various diseases. While kinase research has been a point of focus in biomedical research for several decades, a large portion of the kinome
Externí odkaz:
https://doaj.org/article/0fe77c7a32824f5db32b05dec26eb13a
Autor:
Jennifer Nguyen, Melissa A. Curtis, Ali S. Imami, William G. Ryan, Khaled Alganem, Kari L. Neifer, Nilanjana Saferin, Charlotte N. Nawor, Brian P. Kistler, Gary W. Miller, Rammohan Shukla, Robert E. McCullumsmith
Publikováno v:
Translation, Vol 12, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/19421693822744e0944eb21064314f3a
Publikováno v:
Translation, Vol 11, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/0e21e978c9024a5992c163431153df1c
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S798-S799 (2023)
Externí odkaz:
https://doaj.org/article/6ed0014f3772432fa8d0e250d63a238c
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2815 (2024)
Several types of mood disorders lie along a continuum, with nebulous boundaries between them. Understanding the mechanisms that contribute to mood disorder complexity is critical for effective treatment. However, present treatments are largely center
Externí odkaz:
https://doaj.org/article/2ad2268548ec4e4c8a31fd7c46aee350
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionSynapses and spines play a significant role in major depressive disorder (MDD) pathophysiology, recently highlighted by the rapid antidepressant effect of ketamine and psilocybin. According to the Bayesian brain and interoception perspect
Externí odkaz:
https://doaj.org/article/ebb094a3bc7947dfb4ba6e18de0babe4
Autor:
Nicholas D. Henkel, Marissa A. Smail, Xiaojun Wu, Heather A. Enright, Nicholas O. Fischer, Hunter M. Eby, Robert E. McCullumsmith, Rammohan Shukla
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Animal models have expanded our understanding of temporal lobe epilepsy (TLE). However, translating these to cell-specific druggable hypotheses is not explored. Herein, we conducted an integrative insilico-analysis of an available transcript
Externí odkaz:
https://doaj.org/article/96f33045d9774ed79f416b8982c1c3dd
Autor:
Xiaolu Zhang, Alyssa Wolfinger, Xiaojun Wu, Rawan Alnafisah, Ali Imami, Abdul-rizaq Hamoud, Anna Lundh, Vladimir Parpura, Robert E. McCullumsmith, Rammohan Shukla, Sinead M. O’Donovan
Publikováno v:
Cells, Vol 11, Iss 20, p 3315 (2022)
Astrocytes have many important functions in the brain, but their roles in psychiatric disorders and their responses to psychotropic medications are still being elucidated. Here, we used gene enrichment analysis to assess the relationships between dif
Externí odkaz:
https://doaj.org/article/32c40c538ad443aca32d1f9207a02e20
Autor:
Marissa A. Smail, Sapuni S. Chandrasena, Xiaolu Zhang, Vineet Reddy, Craig Kelley, James P. Herman, Mohamed Sherif, Robert E. McCullumsmith, Rammohan Shukla
Publikováno v:
Mol Psychiatry
In psychiatric disorders, mismatches between disease states and therapeutic strategies are highly pronounced, largely because of unanswered questions regarding specific vulnerabilities of different cell types and therapeutic responses. Which cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602a7e09817dec00672f4cf41057c367
https://doi.org/10.1038/s41380-022-01657-w
https://doi.org/10.1038/s41380-022-01657-w
Autor:
Xiaolu Zhang, Mahmoud Ali Eladawi, William George Ryan, Xiaoming Fan, Stephen Prevoznik, Trupti Devale, Barkha Ramnani, Krishnamurthy Malathi, Etienne Sibille, Robert Mccullumsmith, Toshifumi Tomoda, Rammohan Shukla
The underlying biological mechanisms that contribute to the heterogeneity of major depressive disorder (MDD) presentation remain poorly understood, highlighting the need for a conceptual framework that can explain this variability and bridge the gap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c08b5ff1661c7d9496f65b24c5ea1d6
https://doi.org/10.1101/2023.05.04.539419
https://doi.org/10.1101/2023.05.04.539419
