Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ramina Khoshaba"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundDysfunction of intestinal epithelial cells (IECs) promotes inflammatory bowel disease (IBD) and associated colorectal cancer (CRC). AKR1B8 deficiency impairs the IEC barrier function, leading to susceptibility to chronic colitis induced by
Externí odkaz:
https://doaj.org/article/d65fd734a2744d1ab2726fea3ba47a36
Autor:
Xin Wang, Ramina Khoshaba, Yi Shen, Yu Cao, Minglin Lin, Yun Zhu, Zhe Cao, Duan-Fang Liao, Deliang Cao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Aldo-keto reductase 1B10 (AKR1B10) is downregulated in human ulcerative colitis (UC) and colorectal cancer, being a potential pathogenic factor of these diseases. Aldo-keto reductase 1B8 (AKR1B8) is the ortholog in mice of human AKR1B10. Targeted AKR
Externí odkaz:
https://doaj.org/article/b12cdaf4990e4ffbbe2106a33b6a141b
Autor:
Ying-chun He, Lan He, Ramina Khoshaba, Fang-guo Lu, Chuan Cai, Fang-liang Zhou, Duan-fang Liao, Deliang Cao
Publikováno v:
Molecules, Vol 24, Iss 22, p 4179 (2019)
Curcumin is an anticancer agent, but adverse effects and low bioavailability are its main drawbacks, which drives efforts in chemical modifications of curcumin. This study evaluated antiproliferative activity and cancer cell selectivity of a curcumin
Externí odkaz:
https://doaj.org/article/1d24036e663b4e8f9f0ec6d506fbf970
Autor:
Yan Zhao, Junfei Jin, Gao Han, Hongyan Ling, Chenfei Huang, Qianjin Liao, Ping Wu, Jinjun Chen, Xuewen Zhang, Ramina Khoshaba, Min Su, Zhe Cao, Deliang Cao
Publikováno v:
Journal of Cancer
Long non-coding RNAs (lncRNAs) are non-coding RNAs longer than 200 nucleotides that function as regulatory factors in many human diseases, including cancer. However, majority of lncRNAs remain to be characterized. In this study, we characterized a no
Autor:
Yi Shen, Yu Cao, Minglin Lin, Zhe Cao, Duan-Fang Liao, Xin Wang, Yun Zhu, Deliang Cao, Ramina Khoshaba
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Aldo-keto reductase 1B10 (AKR1B10) is downregulated in human ulcerative colitis (UC) and colorectal cancer, being a potential pathogenic factor of these diseases. Aldo-keto reductase 1B8 (AKR1B8) is the ortholog in mice of human AKR1B10. Targeted AKR
Autor:
Junfei Jin, Dan Huang, Deliang Cao, Duan-Fang Liao, Chenfei Huang, Guiyuan Shi, Haitao Ji, Yi Shen, Yiwen Bu, Jun Ma, Zhe Cao, Ramina Khoshaba
Publikováno v:
Molecular Carcinogenesis. 57:1300-1310
Aldo-keto reductase 1B10 (AKR1B10) is upregulated in breast cancer and promotes tumor growth and metastasis. However, little is known of the molecular mechanisms of action. Herein we report that AKR1B10 activates lipid second messengers to stimulate
Autor:
Chuan Cai, Deliang Cao, Fang-guo Lu, Fangliang Zhou, Duan-Fang Liao, Ramina Khoshaba, Lan He, Yingchun He
Publikováno v:
Molecules
Molecules, Vol 24, Iss 22, p 4179 (2019)
Volume 24
Issue 22
Molecules, Vol 24, Iss 22, p 4179 (2019)
Volume 24
Issue 22
Curcumin is an anticancer agent, but adverse effects and low bioavailability are its main drawbacks, which drives efforts in chemical modifications of curcumin. This study evaluated antiproliferative activity and cancer cell selectivity of a curcumin
Publikováno v:
Science Journal of University of Zakho, Vol 2, Iss 1, Pp 74-85 (2014)
RNA and DNA extracted from formalin-fixed paraffin-embedded (FFPE) tissue is problematic due to chemical modifications and continued degradation over time. we compared quantity of RNA extracted by two different protocols from 14 recently archived fro
Autor:
Ramina Khoshaba, Deliang Cao
Publikováno v:
Cancer Research. 78:3493-3493
Background: Breast cancer is the second most common cause of female cancer-related death in the United States. Aldo-keto reductase 1B10 (AKR1B10) is a 35-kDa protein that is highly expressed in breast cancer in infiltrative and Ductal Carcinoma in Si