Central interaction of ascorbic acid and D2 dopamine receptors on spatial learning and memory in adult male rats

Autor: Sima Nasri, Mehri Bahaaddini, mehdi abbasnejad, Saeed Esmaeili-Mahani, Ramin Raoof

Publikováno v: The Iranian Journal of Veterinary Science and Technology, Vol 6, Iss 1, Pp 1-15 (2014)

Previous studies had reported that extracellular levels of ascorbic acid have modulatory effects on dopamine receptors. Both ascorbic acid and dopamine receptor have an important role in learning and memory processes. However, the central interaction

Externí odkaz: https://doaj.org/article/227438682ef2409b86c4aebaafcbe012

A modification of a previous model for inflammatory tooth pain: Effects of different capsaicin and formalin concentrations and ibuprofen

Autor: Maryam Raoof, Mehdi Abbasnejad, Ladan Amirkhosravi, Hamed Ebrahimnejad, Ramin Raoof

Publikováno v: Journal of Oral Health and Oral Epidemiology, Vol 1, Iss 2, Pp 70-77 (2012)

BACKGROUND: This study aimed to solve the problems faced with the previous model of inflammatory tooth pain in rats. METHODS: After cutting 2 mm of the distal extremities, the polyethylene crowns were placed on the mandibular incisors. In contrast t

Externí odkaz: https://doaj.org/article/3fa5bd1f47f24bc887ea51f9d7002175

Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain

Autor: Michiel van der Vlist, Ramin Raoof, Hanneke L.D.M. Willemen, Judith Prado, Sabine Versteeg, Christian Martin Gil, Martijn Vos, Roeland E. Lokhorst, R. Jeroen Pasterkamp, Toshiyuki Kojima, Hajime Karasuyama, William Khoury-Hanold, Linde Meyaard, Niels Eijkelkamp

Publikováno v: van der Vlist, M, Raoof, R, Willemen, H L D M, Prado, J, Versteeg, S, Martin Gil, C, Vos, M, Lokhorst, R E, Pasterkamp, R J, Kojima, T, Karasuyama, H, Khoury-Hanold, W, Meyaard, L & Eijkelkamp, N 2022, ' Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain ', Neuron, vol. 110, no. 4, pp. 613-626.e9 . https://doi.org/10.1016/j.neuron.2021.11.020
Neuron, 110(4), 613-626.e9. Cell Press
Neuron

SummaryThe current paradigm is that inflammatory pain passively resolves following the cessation of inflammation. Yet, in a substantial proportion of patients with inflammatory diseases, resolution of inflammation is not sufficient to resolve pain, r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d149e7be22ba2dcb911c6b189c1f07
https://research.vumc.nl/en/publications/71f16858-561b-49e8-a95b-101e8da712dc

Dorsal Root Ganglia Macrophages Maintain Osteoarthritis Pain

Autor: John N. Wood, Anne L.P. Heinemans, Simon C. Mastbergen, Judith Prado, R. Jeroen Pasterkamp, Huub M. de Visser, Youri Adolfs, Floris P J G Lafeber, Ramin Raoof, Niels Eijkelkamp, Sabine Versteeg, Christian Martin Gil, Mirte N. Pascha

Publikováno v: J Neurosci
The Journal of Neuroscience

Pain is the major debilitating symptom of osteoarthritis (OA), which is difficult to treat. In OA patients joint tissue damage only poorly associates with pain, indicating other mechanisms contribute to OA pain. Immune cells regulate the sensory syst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4abcadadbe9a6724e151b737fb6c5823
https://pubmed.ncbi.nlm.nih.gov/35086908

Development of Recombinant Proteins to Treat Chronic Pain

Autor: Niels Eijkelkamp, C. Steen-Louws, Ramin Raoof, J. Popov-Celeketic, Judith Prado, Eric Hack

Publikováno v: Journal of Visualized Experiments, 2018(134). MYJoVE Corporation

Chronic pain is difficult to treat and new approaches to resolve persistent pain are urgently needed. Anti-inflammatory cytokines are promising candidates for treating debilitating pain conditions due to their capacity to regulate aberrant neuro-immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a327a873542a08315d173f41066ab752
https://doi.org/10.3791/57071-v