Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Ramin Radpour"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Multiple myeloma (MM) is a hematologic malignancy characterized by the proliferation of clonal plasma cells in the bone marrow (BM). It is known that early genetic mutations in post-germinal center B/plasma cells are the cause of myelomagenesis. The
Externí odkaz:
https://doaj.org/article/0a95875e38f343f3931a95198121c0f3
Publikováno v:
HemaSphere, Vol 7, p e064340f (2023)
Externí odkaz:
https://doaj.org/article/da5875919a854141b428a1bab88ecae5
Autor:
Stefan Forster, Chantal Bachmann, Maxime Boy, Ramin Radpour, Christian Schürch, Carsten Riether, Adrian Ochsenbein
Publikováno v:
HemaSphere, Vol 7, p e9721152 (2023)
Externí odkaz:
https://doaj.org/article/83f64ebe88524e6caca9a64dab058848
Autor:
Kristina Seiler, Magali Humbert, Petra Minder, Iris Mashimo, Anna M. Schläfli, Deborah Krauer, Elena A. Federzoni, Bich Vu, James J. Moresco, John R. Yates, Martin C. Sadowski, Ramin Radpour, Thomas Kaufmann, Jean-Emmanuel Sarry, Joern Dengjel, Mario P. Tschan, Bruce E. Torbett
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-14 (2022)
Abstract The family of hexokinases (HKs) catalyzes the first step of glycolysis, the ATP-dependent phosphorylation of glucose to glucose-6-phosphate. While HK1 and HK2 are ubiquitously expressed, the less well-studied HK3 is primarily expressed in he
Externí odkaz:
https://doaj.org/article/0483ca7b4b974a9db20fe6d5d5f9e6fc
Autor:
Stefan Forster, Ramin Radpour
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Multiple myeloma (MM) is the most common malignant monoclonal disease of plasma cells. Aside from classical chemotherapy and glucocorticoids, proteasome inhibitors, immunomodulatory agents and monoclonal antibodies are used in the current treatment s
Externí odkaz:
https://doaj.org/article/902628d05e784dd7bc01dcee609d6239
Autor:
Carla A. Jaeger-Ruckstuhl, Magdalena Hinterbrandner, Sabine Höpner, Colin E. Correnti, Ursina Lüthi, Olivier Friedli, Stefan Freigang, Mohamad F. Al Sayed, Elias D. Bührer, Michael A. Amrein, Christian M. Schürch, Ramin Radpour, Carsten Riether, Adrian F. Ochsenbein
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Coordinate expression of multiple factors play critical roles in the regulation between effector and memory CD8+ T cell differentiation. Here the authors show upon acute viral infection TNIK is critically required as a regulator of effector and memor
Externí odkaz:
https://doaj.org/article/21c39ff478914e4584620912b78764da
Autor:
Magdalena Hinterbrandner, Viviana Rubino, Carina Stoll, Stefan Forster, Noah Schnüriger, Ramin Radpour, Gabriela M. Baerlocher, Adrian F. Ochsenbein, Carsten Riether
Publikováno v:
JCI Insight, Vol 6, Iss 23 (2021)
Leukemia stem cells (LSCs) promote the disease and seem resistant to therapy and immune control. Why LSCs are selectively resistant against elimination by CD8+ cytotoxic T cells (CTLs) is still unknown. In this study, we demonstrate that LSCs in chro
Externí odkaz:
https://doaj.org/article/aaa5ee6b3a7049b09b48d1e423a16b98
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundImmune-checkpoint (IC) inhibitors have revolutionized the treatment of multiple solid tumors and defined lymphomas, but they are largely ineffective in acute myeloid leukemia (AML). The reason why especially PD1/PD-L1 blocking agents are no
Externí odkaz:
https://doaj.org/article/d2b9914f2fa5454e83b085a5de510bfc
Autor:
Stefan Forster, Ramin Radpour
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The immune system is able to recognize and eliminate tumor cells. Some tumors, including colorectal cancer (CRC), induce immune tolerance via different mechanisms of “immunoediting” and “immune evasion” and can thus escape immune surveillance
Externí odkaz:
https://doaj.org/article/8c4c1d5f2e344aa68479661f9a517089
Autor:
Regula Burkhard, Irene Keller, Miroslav Arambasic, Darius Juskevicius, Alexandar Tzankov, Pontus Lundberg, Rémy Bruggmann, Stephan Dirnhofer, Ramin Radpour, Urban Novak
Publikováno v:
Haematologica, Vol 104, Iss 4 (2019)
Diffuse large B-cell lymphoma is the most common malignant lymphoma in adults. By gene-expression profiling, this lymphoma is divided in three cell-of-origin subtypes with distinct molecular and clinical features. Most lymphomas arise sporadically, y
Externí odkaz:
https://doaj.org/article/a1a224fad48049c9b6a8a5d3dd35ee6c