Výsledky vyhledávání - "Ramiah Sangaiah"

Akademický článek

Ethenoguanines undergo glycosylation by nucleoside 2'-deoxyribosyltransferases at non-natural sites.

Autor: Wenjie Ye, Debamita Paul, Lina Gao, Jolita Seckute, Ramiah Sangaiah, Karupiah Jayaraj, Zhenfa Zhang, P Alexandre Kaminski, Steven E Ealick, Avram Gold, Louise M Ball

Publikováno v: PLoS ONE, Vol 9, Iss 12, p e115082 (2014)

Deoxyribosyl transferases and functionally related purine nucleoside phosphorylases are used extensively for synthesis of non-natural deoxynucleosides as pharmaceuticals or standards for characterizing and quantitating DNA adducts. Hence exploring th

Externí odkaz: https://doaj.org/article/1f8e2d50ab4d4487abe619e7dcb3e613

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Characterization and Quantification of Cysteinyl Adducts of Benzene Diol Epoxide

Autor: Suramya Waidyanatha, Stephen M. Rappaport, Ramiah Sangaiah

Publikováno v: Chemical Research in Toxicology. 18:1178-1185

The production of macromolecular adducts of benzene diol epoxide (BDE), a toxic metabolite of benzene, has received little attention despite the demonstrated mutagenicity and carcinogenicity of BDE in rodents. Syn and anti enantiomers of BDE were rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a604013b01e04f3deb9d1b50d0d44b
https://doi.org/10.1021/tx0500981

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Profiling of ecdysteroids in complex biological samples using liquid chromatography/ion trap mass spectrometry

Autor: Yutai Li, Gunnar Boysen, James T. Warren, Avram Gold, James A. Swenberg, Lawrence I. Gilbert, Ramiah Sangaiah, Louise M. Ball

Publikováno v: Rapid Communications in Mass Spectrometry. 20:185-192

A sensitive method using high-performance liquid chromatography coupled to a mass spectrometer with electrospray ionization source (HPLC/ESI-MS) was developed for detection of ecdysteroids in biological samples. We report here for the first time that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b908c73f86366ad7a061b84cdf7de37
https://doi.org/10.1002/rcm.2294

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Synthesis, Characterization, and Identification of N7-Guanine Adducts of Isoprene Monoepoxides in Vitro

Autor: Ramiah Sangaiah, Bernard T. Golding, A. Gold, James A. Swenberg, Petra Begemann, Daping Zhang, Hasan Koc, † Nadia I. Christova-Georgieva

Publikováno v: Chemical Research in Toxicology. 17:929-936

Isoprene (IP, 2-methylbuta-1,3-diene) is ubiquitous in the environment through emission by plants, combustion processes, and endogenous formation and exhalation by mammals, including humans. IP is also an industrial chemical, widely used in the manuf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f488bd1152990883d1981d8a1b37c4dc
https://doi.org/10.1021/tx0342565

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New immunoaffinity-LC-MS/MS methodology reveals that Aag null mice are deficient in their ability to clear 1,N6-etheno-deoxyadenosine DNA lesions from lung and liver in vivo

Autor: Lisiane B. Meira, James A. Swenberg, Bevin P. Engelward, Amy Joan L Ham, Hasan Koc, Leona D. Samson, Ramiah Sangaiah

Publikováno v: DNA Repair. 3:257-265

The mouse alkyladenine DNA glycosylase (Aag) initiates base excision repair with a broad substrate range that includes the highly mutagenic exocyclic etheno DNA base adduct 1,N6-ethenodeoxyadenosine ((epsilon)dA). Previous attempts to determine the i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba2160bdeabb1ffb1facfbd3ba0a446
https://doi.org/10.1016/j.dnarep.2003.11.003

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SYNTHESIS OFS-ARYL-D,L-CYSTEINES AND INCORPORATION INTO KERATIN SEQUENCES

Autor: K. Jayaraj, Leena A. Nylander-French, David G. Klapper, Tae-gyu Nam, Avram Gold, Ramiah Sangaiah, Louise M. Ball, John E. French

Publikováno v: Organic Preparations and Procedures International. 35:375-382

(2003). SYNTHESIS OF S-ARYL-D,L-CYSTEINES AND INCORPORATION INTO KERATIN SEQUENCES. Organic Preparations and Procedures International: Vol. 35, No. 4, pp. 375-382.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23aa9a9b394d7e72e3f35bead9c1fbc8
https://doi.org/10.1080/00304940309355843

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The effect of aging on pyrene transformation in sediments

Autor: Avram Gold, Myrna J. Salloum, Adam Grasham, Ramiah Sangaiah, Elizabeth Guthrie-Nichols, Jacqueline M. Bortiatynski, Patrick G. Hatcher, Chikoma Kazunga

Publikováno v: Scopus-Elsevier

The effect of aging on pyrene transformation and pyrene association with fractions of the sedimentary organic matrix (SdOM) was evaluated using [4,9-(13)C2]pyrene. Sediments were collected from a site of previous petroleum hydrocarbon contamination (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aae6e5f914080aa88aff92b625e83f1
https://doi.org/10.1002/etc.5620220106

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Synthesis of FMOC-Protected S -arylcysteines and Modified Keratin Sequence Peptides as Specific Epitopes as Immunogens

Autor: Leena A. Nylander-French, Gregory D. Lacks, Tae-gyu Nam, John E. French, Avram Gold, Ramiah Sangaiah

Publikováno v: Polycyclic Aromatic Compounds. 22:239-248

The sulfhydryl group of cysteine residues is a site for the adduction of ultimate carcinogenic arene oxide metabolites to the proteins keratin 1 and keratin 10, dominant proteins of the squame. The putative cysteine adducts are: S -phenylcysteine, fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b3e8c2d77d89cc900eb354b14cf59c4
https://doi.org/10.1080/10406630290026885

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Identification of Stereochemical Configurations of Cyclopenta[ cd ]pyrene DNA Adducts in Strain A/J Mouse Lung and C3H10T1/2CL8 Cells

Autor: Avram Gold, Ramiah Sangaiah, Jeffrey S. Ross, Garret B. Nelson, Candace M. Prusiewicz

Publikováno v: Polycyclic Aromatic Compounds. 22:923-931

Four major and several minor DNA adducts were resolved by 32 P-postlabeling analysis of DNA from strain A/J mouse lung and C3H10T1/2CL8 (C3H10T1/2) mouse embryo fibroblasts treated with cyclopenta[ cd ]pyrene (CPP). The identical pattern of adducts w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d9a5b8aa92527a27ead1a3ef3a2e542
https://doi.org/10.1080/10406630290104086

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Ethenoguanines undergo glycosylation by nucleoside 2'-deoxyribosyltransferases at non-natural sites

Autor: Jolita Seckute, K. Jayaraj, Louise M. Ball, Avram Gold, Wenjie Ye, P. Alexandre Kaminski, Steven E. Ealick, Debamita Paul, Zhenfa Zhang, Lina Gao, Ramiah Sangaiah

Publikováno v: PLoS ONE, Vol 9, Iss 12, p e115082 (2014)
PLoS ONE
PLoS ONE, Public Library of Science, 2014, 9 (12), pp.e115082. ⟨10.1371/journal.pone.0115082⟩
PLoS ONE, 2014, 9 (12), pp.e115082. ⟨10.1371/journal.pone.0115082⟩

International audience; Deoxyribosyl transferases and functionally related purine nucleoside phosphorylases are used extensively for synthesis of non-natural deoxynucleosides as pharmaceuticals or standards for characterizing and quantitating DNA add

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfa0ae4e56a38b6af092894f1922143
http://europepmc.org/articles/PMC4270796?pdf=render

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