Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rami Owera"'
Autor:
Rami Owera, Roger M. Lyons, Sudhir Manda, Philip Twumasi-Ankrah, Kimberly Bogard, Yikun Guo, Presley Whidden, Stephen J. Noga, Ruemu Ejedafeta Birhiray, Saulius Girnius, Leon Bernal-Mizrachi, Habte A. Yimer, Robert M. Rifkin
Publikováno v:
Blood. 138:2726-2726
Background: Use of long-term PI-based therapy can improve outcomes across treatment settings in MM. However, there are various physical, geographical, and/or socioeconomic barriers to prolonged therapy with parenteral PIs in community practice. The U
Autor:
Rami Owera, Howard A. Burris, Mathew John Joseph, Ruth E. Lamar, David R. Spigel, Johanna C. Bendell, Cassie M. Lane, D. S. Thompson, Chris Earwood, William Penley, Todd M. Bauer
Publikováno v:
Cancer Investigation. 34:265-270
AUY922 is an inhibitor of heat shock protein 90 (Hsp90). Hsp90 inhibitors induce kit degradation in preclinical gastrointestinal stromal tumor (GIST) models. This trial was designed to determine the progression-free survival (PFS) of patients with GI
Autor:
Ian W. Flinn, Jesus G. Berdeja, Lowell L. Hart, Joseph R. Mace, Rami Owera, John D. Hainsworth, Edward Arrowsmith, James Essell
Publikováno v:
Haematologica. 100(5)
The purpose of this study was to assess the safety and efficacy of the combination of panobinostat and carfilzomib in patients with relapsed/refractory multiple myeloma. Patients with multiple myeloma who had relapsed after at least one prior treatme
Autor:
Lowell L. Hart, Rami Owera, Jeffrey Matous, Edward A. Faber, Tara K. Gregory, James Essell, Jesus G. Berdeja, Ian W. Flinn, Joseph R. Mace
Publikováno v:
Journal of Clinical Oncology. 33:8513-8513
8513 Background: Histone deacetylase inhibitors (HDACi) and proteasome inhibitors (PI) act synergistically through inhibition of the proteasome and aggresome pathways. We have previously reported t...