Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Rami Nassir"'
Autor:
Ghislain Rocheleau, Shoa L. Clarke, Gaëlle Auguste, Natalie R. Hasbani, Alanna C. Morrison, Adam S. Heath, Lawrence F. Bielak, Kruthika R. Iyer, Erica P. Young, Nathan O. Stitziel, Goo Jun, Cecelia Laurie, Jai G. Broome, Alyna T. Khan, Donna K. Arnett, Lewis C. Becker, Joshua C. Bis, Eric Boerwinkle, Donald W. Bowden, April P. Carson, Patrick T. Ellinor, Myriam Fornage, Nora Franceschini, Barry I. Freedman, Nancy L. Heard-Costa, Lifang Hou, Yii-Der Ida Chen, Eimear E. Kenny, Charles Kooperberg, Brian G. Kral, Ruth J. F. Loos, Sharon M. Lutz, JoAnn E. Manson, Lisa W. Martin, Braxton D. Mitchell, Rami Nassir, Nicholette D. Palmer, Wendy S. Post, Michael H. Preuss, Bruce M. Psaty, Laura M. Raffield, Elizabeth A. Regan, Stephen S. Rich, Jennifer A. Smith, Kent D. Taylor, Lisa R. Yanek, Kendra A. Young, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Austin T. Hilliard, Catherine Tcheandjieu, Patricia A. Peyser, Ramachandran S. Vasan, Jerome I. Rotter, Clint L. Miller, Themistocles L. Assimes, Paul S. de Vries, Ron Do
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Whole genome sequences (WGS) enable discovery of rare variants which may contribute to missing heritability of coronary artery disease (CAD). To measure their contribution, we apply the GREML-LDMS-I approach to WGS of 4949 cases and 17,494 c
Externí odkaz:
https://doaj.org/article/06f5575dd28f4c74ac4e7a972d07a02f
Autor:
Cameron B. Haas, Yu-Ru Su, Paneen Petersen, Xiaoliang Wang, Stephanie A. Bien, Yi Lin, Demetrius Albanes, Stephanie J. Weinstein, Mark A. Jenkins, Jane C. Figueiredo, Polly A. Newcomb, Graham Casey, Loic Le Marchand, Peter T. Campbell, Victor Moreno, John D. Potter, Lori C. Sakoda, Martha L. Slattery, Andrew T. Chan, Li Li, Graham G. Giles, Roger L. Milne, Stephen B. Gruber, Gad Rennert, Michael O. Woods, Steven J. Gallinger, Sonja Berndt, Richard B. Hayes, Wen-Yi Huang, Alicja Wolk, Emily White, Hongmei Nan, Rami Nassir, Noralane M. Lindor, Juan P. Lewinger, Andre E. Kim, David Conti, W. James Gauderman, Daniel D. Buchanan, Ulrike Peters, Li Hsu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Observational studies have shown higher folate consumption to be associated with lower risk of colorectal cancer (CRC). Understanding whether and how genetic risk factors interact with folate could further elucidate the underlying mechanism.
Externí odkaz:
https://doaj.org/article/ea55fb50ab2146d2930d6881db425e35
Autor:
Peter Georgeson, Tabitha A. Harrison, Bernard J. Pope, Syed H. Zaidi, Conghui Qu, Robert S. Steinfelder, Yi Lin, Jihoon E. Joo, Khalid Mahmood, Mark Clendenning, Romy Walker, Efrat L. Amitay, Sonja I. Berndt, Hermann Brenner, Peter T. Campbell, Yin Cao, Andrew T. Chan, Jenny Chang-Claude, Kimberly F. Doheny, David A. Drew, Jane C. Figueiredo, Amy J. French, Steven Gallinger, Marios Giannakis, Graham G. Giles, Andrea Gsur, Marc J. Gunter, Michael Hoffmeister, Li Hsu, Wen-Yi Huang, Paul Limburg, JoAnn E. Manson, Victor Moreno, Rami Nassir, Jonathan A. Nowak, Mireia Obón-Santacana, Shuji Ogino, Amanda I. Phipps, John D. Potter, Robert E. Schoen, Wei Sun, Amanda E. Toland, Quang M. Trinh, Tomotaka Ugai, Finlay A. Macrae, Christophe Rosty, Thomas J. Hudson, Mark A. Jenkins, Stephen N. Thibodeau, Ingrid M. Winship, Ulrike Peters, Daniel D. Buchanan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Germline biallelic pathogenic MUTYH variants predispose patients to colorectal cancer (CRC); however, approaches to identify MUTYH variant carriers are lacking. Here, the authors evaluated mutational signatures that could distinguish MUTYH carriers i
Externí odkaz:
https://doaj.org/article/333b1f57f922432c8d0bf0c51f25cb70
Autor:
Christina M. Dieli-Conwright, Rebecca A. Nelson, Michael S. Simon, Melinda L. Irwin, Marian L. Neuhouser, Kerryn W. Reding, Tracy E. Crane, JoAnn E. Manson, Rami Nassir, Aladdin H. Shadyab, Michael LaMonte, Lihing Qi, Cynthia A. Thomson, Candyce H. Kroenke, Kathy Pan, Rowan T. Chlebowski, Joanne Mortimer
Publikováno v:
BMC Women's Health, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background Higher physical activity levels are associated with lower breast cancer-specific mortality. In addition, the metabolic syndrome is associated with higher breast cancer-specific mortality. Whether the physical activity association
Externí odkaz:
https://doaj.org/article/e4ce9f34d86348ffa0dd04fd850a134a
Autor:
Julia D. Labadie, Sevtap Savas, Tabitha A. Harrison, Barb Banbury, Yuhan Huang, Daniel D. Buchanan, Peter T. Campbell, Steven J. Gallinger, Graham G. Giles, Marc J. Gunter, Michael Hoffmeister, Li Hsu, Mark A. Jenkins, Yi Lin, Shuji Ogino, Amanda I. Phipps, Martha L. Slattery, Robert S. Steinfelder, Wei Sun, Bethany Van Guelpen, Xinwei Hua, Jane C. Figuieredo, Rish K. Pai, Rami Nassir, Lihong Qi, Andrew T. Chan, Ulrike Peters, Polly A. Newcomb
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Identification of new genetic markers may improve the prediction of colorectal cancer prognosis. Our objective was to examine genome-wide associations of germline genetic variants with disease-specific survival in an analysis of 16,964 cases
Externí odkaz:
https://doaj.org/article/e0cd1a5fbff641d297b2c3ffd001479d
Autor:
Mandana Kamgar, Mark K. Greenwald, Hadeel Assad, Theresa A. Hastert, Eric M. McLaughlin, Kerryn W Reding, Electra D. Paskett, Jennifer W. Bea, Aladdin H. Shadyab, Marian L. Neuhouser, Rami Nassir, Tracy E. Crane, Kalyan Sreeram, Michael S. Simon
Publikováno v:
Cancer Medicine, Vol 10, Iss 19, Pp 6666-6676 (2021)
Abstract Background Many of the 3.8 million breast cancer survivors in the United States experience long‐term side effects of cancer therapy including peripheral neuropathy (PN). We assessed the prevalence and predictors of PN among women with brea
Externí odkaz:
https://doaj.org/article/bff4dda41e6d472faffc036b2fd2aac1
Autor:
Kristina M. Jordahl, Amanda I. Phipps, Timothy W. Randolph, Lesley F. Tinker, Rami Nassir, Lifang Hou, Garnet L. Anderson, Karl T. Kelsey, Emily White, Parveen Bhatti
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background Though bladder cancer has been the subject of many well-powered genome-wide association studies, the mechanisms involving bladder-cancer-associated single nucleotide polymorphisms (SNPs) remain largely unknown. This study focuses
Externí odkaz:
https://doaj.org/article/2f1ea7d278404494b0d3bb30ff8d2e0a
Autor:
Zhiyu Xia, Yu‐Ru Su, Paneen Petersen, Lihong Qi, Andre E. Kim, Jane C. Figueiredo, Yi Lin, Hongmei Nan, Lori C. Sakoda, Demetrius Albanes, Sonja I. Berndt, Stéphane Bézieau, Stephanie Bien, Daniel D. Buchanan, Graham Casey, Andrew T. Chan, David V. Conti, David A. Drew, Steven J. Gallinger, W. James Gauderman, Graham G. Giles, Stephen B. Gruber, Marc J. Gunter, Michael Hoffmeister, Mark A. Jenkins, Amit D. Joshi, Loic Le Marchand, Juan P. Lewinger, Li Li, Noralane M. Lindor, Victor Moreno, Neil Murphy, Rami Nassir, Polly A. Newcomb, Shuji Ogino, Gad Rennert, Mingyang Song, Xiaoliang Wang, Alicja Wolk, Michael O. Woods, Hermann Brenner, Emily White, Martha L. Slattery, Edward L. Giovannucci, Jenny Chang‐Claude, Paul D. P. Pharoah, Li Hsu, Peter T. Campbell, Ulrike Peters
Publikováno v:
Cancer Medicine, Vol 9, Iss 10, Pp 3563-3573 (2020)
Abstract Background Body mass index (BMI) and diabetes are established risk factors for colorectal cancer (CRC), likely through perturbations in metabolic traits (e.g. insulin resistance and glucose homeostasis). Identification of interactions betwee
Externí odkaz:
https://doaj.org/article/ca873e6d162b46648933e4b0b52bd613
Autor:
Ha My T, Vy, Bridget M, Lin, Faris F, Gulamali, Charles, Kooperberg, Mariaelisa, Graff, Jenny, Wong, Kirk N, Campbell, Tara C, Matise, Josef, Coresh, Fridtjof, Thomas, Alexander P, Reiner, Rami, Nassir, Peter F, Schnatz, Tanya, Johns, Steven, Buyske, Christopher, Haiman, Richard, Cooper, Ruth J F, Loos, Carol R, Horowitz, Orlando M, Gutierrez, Ron, Do, Nora, Franceschini, Girish N, Nadkarni
Publikováno v:
Clinical journal of the American Society of Nephrology : CJASN.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8ce52eaa09e8312be13408029343de2
https://pubmed.ncbi.nlm.nih.gov/35948364
https://pubmed.ncbi.nlm.nih.gov/35948364
Autor:
Whitney L. Do, Dianjianyi Sun, Karlijn Meeks, Pierre-Antoine Dugué, Ellen Demerath, Weihua Guan, Shengxu Li, Wei Chen, Roger Milne, Abedowale Adeyemo, Charles Agyemang, Rami Nassir, JoAnn E. Manson, Aladdin H. Shadyab, Lifang Hou, Steve Horvath, Themistocles L. Assimes, Parveen Bhatti, Kristina M. Jordahl, Andrea A. Baccarelli, Alicia K. Smith, Lisa R. Staimez, Aryeh D. Stein, Eric A. Whitsel, K.M. Venkat Narayan, Karen N. Conneely
Publikováno v:
American journal of human genetics, 110(2), 273-283. Cell Press
This study sought to examine the association between DNA methylation and body mass index (BMI) and the potential of BMI-associated cytosine-phosphate-guanine (CpG) sites to provide information about metabolic health. We pooled summary statistics from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b89637a5d1946ead3a03fb2fa48d5d8
http://www.scopus.com/inward/record.url?scp=85147457765&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85147457765&partnerID=8YFLogxK