Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Rami Al Batran"'
Autor:
Stephanie Mourad, Abdualrahman Mohammed Abdualkader, Xiaobei Li, Shailee Jani, Rolando B. Ceddia, Rami Al Batran
Publikováno v:
Experimental Physiology, Vol 109, Iss 3, Pp 350-364 (2024)
Abstract Non‐alcoholic fatty liver disease (NAFLD) is projected to be the most common chronic liver disease worldwide and is closely linked to obesity, insulin resistance and type 2 diabetes. Currently, no pharmacological treatments are available t
Externí odkaz:
https://doaj.org/article/8aa6357aaacb4f15a81299f995fb6b9f
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 27 (2024)
Elevated levels of circulating branched-chain amino acids (BCAAs) and their associated metabolites have been strongly linked to insulin resistance and type 2 diabetes. Despite extensive research, the precise mechanisms linking increased BCAA levels w
Externí odkaz:
https://doaj.org/article/0e53105a49344e95a6a45ed9acbecc42
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 10 (2023)
Purpose of review: Glomerulonephritis refers to a rare group of diseases characterized by glomerular inflammation, which collectively are a common cause of kidney failure. Until recently, there was a lack of high-quality clinical trials to inform the
Externí odkaz:
https://doaj.org/article/08ab217732274b46a552171c82093f2f
Autor:
Golam M. Uddin, Liyan Zhang, Saumya Shah, Arata Fukushima, Cory S. Wagg, Keshav Gopal, Rami Al Batran, Simran Pherwani, Kim L. Ho, Jamie Boisvenue, Qutuba G. Karwi, Tariq Altamimi, David S. Wishart, Jason R. B. Dyck, John R. Ussher, Gavin Y. Oudit, Gary D. Lopaschuk
Publikováno v:
Cardiovascular Diabetology, Vol 18, Iss 1, Pp 1-12 (2019)
Abstract Background Branched chain amino acids (BCAA) can impair insulin signaling, and cardiac insulin resistance can occur in the failing heart. We, therefore, determined if cardiac BCAA accumulation occurs in patients with dilated cardiomyopathy (
Externí odkaz:
https://doaj.org/article/1825257d7b364b2bb61f4a044c96565b
Autor:
Keshav Gopal, Rami Al Batran, Tariq R. Altamimi, Amanda A. Greenwell, Christina T. Saed, Seyed Amirhossein Tabatabaei Dakhili, M. Toni E. Dimaano, Yongneng Zhang, Farah Eaton, Gopinath Sutendra, John R. Ussher
Publikováno v:
Cell Reports, Vol 35, Iss 1, Pp 108935- (2021)
Summary: Type 2 diabetes (T2D) increases the risk for diabetic cardiomyopathy and is characterized by diastolic dysfunction. Myocardial forkhead box O1 (FoxO1) activity is enhanced in T2D and upregulates pyruvate dehydrogenase (PDH) kinase 4 expressi
Externí odkaz:
https://doaj.org/article/c68c21dfb4204bab9f1c90e933d24e88
Autor:
Yean K. Yong, Alireza Saeidi, Hong Y. Tan, Mohamed Rosmawati, Philip F. Enström, Rami Al Batran, V. Vasuki, Indranil Chattopadhyay, Amudhan Murugesan, Ramachandran Vignesh, Adeeba Kamarulzaman, Jayakumar Rajarajeswaran, Abdul W. Ansari, Jamuna Vadivelu, James E. Ussher, Vijayakumar Velu, Marie Larsson, Esaki M. Shankar
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Mucosal-associated invariant T (MAIT) cells, defined as CD161++TCR iVα7.2+ T cells, play an important role in the innate defense against bacterial infections, and their functionality is impaired in chronic viral infections. Here, we investigated the
Externí odkaz:
https://doaj.org/article/3de5a270ec254a57b7a02d7dad1d335b
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Obesity and type 2 diabetes (T2D) increase the risk for cardiomyopathy, which is the presence of ventricular dysfunction in the absence of underlying coronary artery disease and/or hypertension. As myocardial energy metabolism is altered during obesi
Externí odkaz:
https://doaj.org/article/340f687229c24e099d0fa6cac671cde1
Autor:
Maryam Hajrezaie, NurAin Salehen, Hamed Karimian, Maryam Zahedifard, Keivan Shams, Rami Al Batran, Nazia Abdul Majid, Shaden A M Khalifa, Hapipah Mohd Ali, Hesham El-Seedi, Mahmood Ameen Abdulla
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121529 (2015)
Biochanin A notable bioactive compound which is found in so many traditional medicinal plant. In vivo study was conducted to assess the protective effect of biochanin A on the gastric wall of Spraguedawley rats` stomachs.The experimental set included
Externí odkaz:
https://doaj.org/article/abeb802b12204f01a8ff505dba3de3dd
Autor:
Mazen M. Jamil Al-Obaidi, Fouad Hussain Al-Bayaty, Rami Al Batran, Jamal Hussaini, Goot Heah Khor
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
Objectives. To estimate the impact of ellagic acid (EA) towards healing tooth socket in diabetic animals, after tooth extraction. Methods. Twenty-four Sprague Dawley male rats weighing 250–300 g were selected for this study. All animals were intrap
Externí odkaz:
https://doaj.org/article/008cb963146d466fbabb49b00f2963f5
Autor:
Rami Al Batran, Fouad Al-Bayaty, Mazen M Jamil Al-Obaidi, Abdualrahman Mohammed Abdualkader, Hamid A Hadi, Hapipah Mohd Ali, Mahmood Ameen Abdulla
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64751 (2013)
BACKGROUND: The current study was carried out to examine the gastroprotective effects of Parkia speciosa against ethanol-induced gastric mucosa injury in rats. METHODOLOGY/PRINCIPAL FINDINGS: Sprague Dawley rats were separated into 7 groups. Groups 1
Externí odkaz:
https://doaj.org/article/238f80b371444a42818f62ad429e4488