Zobrazeno 1 - 10
of 674
pro vyhledávání: '"Rami, I."'
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Breast cancer is the leading cause of cancer-related deaths in women worldwide, with the basal-like or triple-negative breast cancer (TNBC) subtype being particularly aggressive and challenging to treat. Understanding the molecular mechanism
Externí odkaz:
https://doaj.org/article/fde5a074f8b34b6c86d4bd817fca586a
Autor:
Rania Akkawi, Osama Hidmi, Ameen Haj-Yahia, Jonathon Monin, Judith Diment, Yotam Drier, Gary S. Stein, Rami I. Aqeilan
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Osteosarcoma is an aggressive bone tumor that primarily affects children and adolescents. This malignancy is highly aggressive, associated with poor clinical outcomes, and primarily metastasizes to the lungs. Due to its rarity and biological
Externí odkaz:
https://doaj.org/article/b7c6c86beeae4632904277595d6451d7
Publikováno v:
In iScience 15 March 2024 27(3)
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109082- (2024)
Summary: DNA double-stranded breaks (DSBs) pose a significant threat to genomic integrity, and their generation during essential cellular processes like transcription remains poorly understood. In this study, we employ several techniques to map DSBs,
Externí odkaz:
https://doaj.org/article/592fa70aca8c4830b099e4eab335784a
Autor:
Rami, I.1 (AUTHOR), Zerrouki, D.1 (AUTHOR), Assarrar, I.1 (AUTHOR), Rouf, S.1,2 (AUTHOR), Latrech, H.1,2 (AUTHOR) hlatrech@hotmail.fr
Publikováno v:
Journal of Medical Case Reports. 3/30/2024, Vol. 18 Issue 1, p1-7. 7p.
Autor:
Hussam Husanie, Muhannad Abu-Remaileh, Kian Maroun, Lina Abu-Tair, Hazem Safadi, Karine Atlan, Talia Golan, Rami I. Aqeilan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-14 (2022)
Abstract Pancreatic cancer is one of the most lethal cancers, owing to its late diagnosis and resistance to chemotherapy. The tumor suppressor WW domain-containing oxidoreductase (WWOX), one of the most active fragile sites in the human genome (FRA16
Externí odkaz:
https://doaj.org/article/524624a72b364e70afa3e58a7f89ab8c
Autor:
Rania Akkawi, Osama Hidmi, Ameen Haj-Yahia, Jonathon Monin, Judith Diment, Yotam Drier, Gary S. Stein, Rami I. Aqeilan
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/361609d8615846cf933c4b0dfd51deff
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 12, Pp 1-15 (2021)
Abstract WW domain‐containing oxidoreductase (WWOX) is an emerging neural gene‐regulating homeostasis of the central nervous system. Germline biallelic mutations in WWOX cause WWOX‐related epileptic encephalopathy (WOREE) syndrome and spinocere
Externí odkaz:
https://doaj.org/article/b0c97a48d8e64ff2bf3b116d611d7e9f
Autor:
Daniel J Steinberg, Srinivasarao Repudi, Afifa Saleem, Irina Kustanovich, Sergey Viukov, Baraa Abudiab, Ehud Banne, Muhammad Mahajnah, Jacob H Hanna, Shani Stern, Peter L Carlen, Rami I Aqeilan
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 8, Pp 1-20 (2021)
Abstract Developmental and epileptic encephalopathies (DEE) are a group of disorders associated with intractable seizures, brain development, and functional abnormalities, and in some cases, premature death. Pathogenic human germline biallelic mutati
Externí odkaz:
https://doaj.org/article/87977a9dce6149adbe8551e943f5992a
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