Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ramesh Yelagandula"'
Autor:
Manuel Matzinger, Anna Schmücker, Ramesh Yelagandula, Karel Stejskal, Gabriela Krššáková, Frédéric Berger, Karl Mechtler, Rupert L. Mayer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Comprehensive proteomic analysis is essential to elucidate molecular pathways and protein functions. Despite tremendous progress in proteomics, current studies still suffer from limited proteomic coverage and dynamic range. Here, we utilize
Externí odkaz:
https://doaj.org/article/3af4c2b140ba43258f5b316c468cabdc
Autor:
Daniel Bsteh, Hagar F. Moussa, Georg Michlits, Ramesh Yelagandula, Jingkui Wang, Ulrich Elling, Oliver Bell
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Polycomb Repressive Complexes 1 and 2 (PRC1, PRC2) are conserved epigenetic regulators that promote transcriptional gene silencing. PRC1 and PRC2 converge on shared targets, catalyzing repressive histone modifications. Additionally, a subset
Externí odkaz:
https://doaj.org/article/379fd97303e44e788e28099f795e01ac
Autor:
Gintautas Vainorius, Maria Novatchkova, Georg Michlits, Juliane Christina Baar, Cecilia Raupach, Joonsun Lee, Ramesh Yelagandula, Marius Wernig, Ulrich Elling
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Ascl1 and Ngn2, closely related proneural transcription factors, are able to convert mouse embryonic stem cells into induced neurons. Despite their similarities, these factors elicit only partially overlapping transcriptional programs, and i
Externí odkaz:
https://doaj.org/article/be3b505e9315435b88d215c8c6ad0e64
Autor:
Bhagyshree Jamge, Zdravko J Lorković, Elin Axelsson, Akihisa Osakabe, Vikas Shukla, Ramesh Yelagandula, Svetlana Akimcheva, Annika Luisa Kuehn, Frédéric Berger
Publikováno v:
eLife, Vol 12 (2023)
How different intrinsic sequence variations and regulatory modifications of histones combine in nucleosomes remain unclear. To test the importance of histone variants in the organization of chromatin we investigated how histone variants and histone m
Externí odkaz:
https://doaj.org/article/dac2ee6289964c7d9ca29f8ff76e2ac6
Autor:
Ramesh Yelagandula, Aleksandr Bykov, Alexander Vogt, Robert Heinen, Ezgi Özkan, Marcus Martin Strobl, Juliane Christina Baar, Kristina Uzunova, Bence Hajdusits, Darja Kordic, Erna Suljic, Amina Kurtovic-Kozaric, Sebija Izetbegovic, Justine Schaeffer, Peter Hufnagl, Alexander Zoufaly, Tamara Seitz, VCDI, Manuela Födinger, Franz Allerberger, Alexander Stark, Luisa Cochella, Ulrich Elling
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Massively parallel but cost-effective testing is essential to monitor the spread of pathogenic agents. Here the authors present SARSseq, which uses a dual indexing strategy in a multiplexed RT-PCR reaction to diagnose SARS-CoV-2 at scale.
Externí odkaz:
https://doaj.org/article/0518f16f78d04013b649658b4426b654
Autor:
Pierre Bourguet, Colette L. Picard, Ramesh Yelagandula, Thierry Pélissier, Zdravko J. Lorković, Suhua Feng, Marie-Noëlle Pouch-Pélissier, Anna Schmücker, Steven E. Jacobsen, Frédéric Berger, Olivier Mathieu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
T-DNA mutants have been widely used for Arabidopsis gene function characterization. Here, by characterizing a null mutant created by CRISPR, the authors show that previous reported function of H2A.W is confounded by a T-DNA insertion induced chromoso
Externí odkaz:
https://doaj.org/article/9596bb5dd9224f26a484c8b0ae24c391
Autor:
Hagar F. Moussa, Daniel Bsteh, Ramesh Yelagandula, Carina Pribitzer, Karin Stecher, Katarina Bartalska, Luca Michetti, Jingkui Wang, Jorge A. Zepeda-Martinez, Ulrich Elling, Jacob I. Stuckey, Lindsey I. James, Stephen V. Frye, Oliver Bell
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Polycomb Repressive Complexes PRC1 and PRC2 catalyse distinct chromatin modifications to promote gene silencing. Here the authors use reversible tethering of Polycomb proteins to ectopic sites in mouse ESCs and find that canonical but not variant PRC
Externí odkaz:
https://doaj.org/article/c3dcbf63ea4b486cbed795c1f715237f
Autor:
Danhua Jiang, Michael Borg, Zdravko J Lorković, Sean A Montgomery, Akihisa Osakabe, Ramesh Yelagandula, Elin Axelsson, Frédéric Berger
Publikováno v:
PLoS Genetics, Vol 16, Iss 7, p e1008964 (2020)
Chromatin regulation of eukaryotic genomes depends on the formation of nucleosome complexes between histone proteins and DNA. Histone variants, which are diversified by sequence or expression pattern, can profoundly alter chromatin properties. While
Externí odkaz:
https://doaj.org/article/803ed707817a4d94a373fe359fe9d11e
Autor:
Heike Wollmann, Hume Stroud, Ramesh Yelagandula, Yoshiaki Tarutani, Danhua Jiang, Li Jing, Bhagyshree Jamge, Hidenori Takeuchi, Sarah Holec, Xin Nie, Tetsuji Kakutani, Steven E. Jacobsen, Frédéric Berger
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background Gene bodies of vertebrates and flowering plants are occupied by the histone variant H3.3 and DNA methylation. The origin and significance of these profiles remain largely unknown. DNA methylation and H3.3 enrichment profiles over
Externí odkaz:
https://doaj.org/article/309b68733c864f8f9abc52d10f581c2f
Autor:
Tomokazu Kawashima, Daisuke Maruyama, Murat Shagirov, Jing Li, Yuki Hamamura, Ramesh Yelagandula, Yusuke Toyama, Frédéric Berger
Publikováno v:
eLife, Vol 3 (2014)
In animals, microtubules and centrosomes direct the migration of gamete pronuclei for fertilization. By contrast, flowering plants have lost essential components of the centrosome, raising the question of how flowering plants control gamete nuclei mi
Externí odkaz:
https://doaj.org/article/18d6328d9146499bad458730749ce161