Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Ramesh Saxena"'
Autor:
Ting Zhang, Kamala Vanarsa, Ramesh Saxena, Chandra Mohan, C C Mok, Jack Hutcheson, Sneha Ravi Kumar, Satyavani Nukala, Haleigh Inthavong, Bruce Stanley, Tianfu Wu
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss 1 (2024)
Objective Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disorder with no reliable serum biomarkers currently available other than autoantibodies.Methods In the present study, isobaric tags for relative and absolute quantitation-
Externí odkaz:
https://doaj.org/article/11795427f92d4f60b99c4b0f5328a05a
Publikováno v:
Biosensors, Vol 14, Iss 3, p 147 (2024)
To improve the efficiency and patient coverage of the current healthcare system, user-friendly novel homecare devices are urgently needed. In this work, we developed a smartphone-based analyzing and reporting system (SBARS) for biomarker detection in
Externí odkaz:
https://doaj.org/article/c55e42a37d9946dc9a8dd7a4e22e389f
Autor:
Yiwei Shen, Kamala Vanarsa, Zhihua Yin, Ting Zhang, Jessica Castillo, Min Dai, Linghua Zou, Ling Qin, Jieying Wang, Qiang Guo, Ramesh Saxena, Michelle Petri, Nan Shen, Zhizhong Ye, Chandra Mohan, Huihua Ding
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/e00b8c3f68a34c1198336fbbbe95a6d5
Publikováno v:
Biosensors, Vol 14, Iss 2, p 98 (2024)
The goal of this study is to develop a rapid diagnostic test for rheumatic disease and systemic lupus erythematosus (SLE) screening. A novel rapid vertical flow assay (VFA) was engineered and used to assay anti-nuclear (ANA) and anti-dsDNA (αDNA) au
Externí odkaz:
https://doaj.org/article/614f4ce7f3ba4450b88a09b75fd0f5c0
Autor:
Yiwei Shen, Kamala Vanarsa, Zhihua Yin, Ting Zhang, Jessica Castillo, Min Dai, Linghua Zou, Ling Qin, Jieying Wang, Qiang Guo, Ramesh Saxena, Michelle Petri, Nan Shen, Zhizhong Ye, Chandra Mohan, Huihua Ding
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectiveThere is an urgent need for novel biomarkers in lupus nephritis (LN). We report a non-invasive urinary biomarker, L-selectin, in two independent multi-ethnic cohorts.MethodsuL-selectin was tested cross-sectionally in a Chinese cohort (n=255)
Externí odkaz:
https://doaj.org/article/1c1913da6f124872a0bad48cc8acaad7
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionThe current gold standard used for urine biomarker normalization, creatinine, poses a challenge to translate to the point of care because antibodies to creatinine are difficult to develop and currently available ligands to creatinine are
Externí odkaz:
https://doaj.org/article/92d8b02358304cf2b8f7ef0fed8e894e
Autor:
Chenling Tang, Min Fang, Gongjun Tan, Shu Zhang, Bowen Yang, Yaxi Li, Ting Zhang, Ramesh Saxena, Chandra Mohan, Tianfu Wu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveThe goal is to discover novel circulating immune complexes (ICx) in the serum of lupus nephritis (LN) as potential biomarkers.MethodsProtein A/G magnetic beads or C1q-coated plates were used to capture ICx in the serum of LN, followed by the
Externí odkaz:
https://doaj.org/article/5051315251984f19809a10241b89e31c
Publikováno v:
Case Reports in Nephrology and Dialysis, Vol 10, Iss 3, Pp 147-153 (2020)
Most episodes of peritoneal dialysis (PD)-associated peritonitis are caused by skin-dwelling gram-positive bacteria and gram-negative bacteria colonizing gut and urinary tract. Occasionally, however, uncommon bacteria can cause peritonitis in PD pati
Externí odkaz:
https://doaj.org/article/348ab161a42443bdb86c15ea8d437150
Autor:
Samantha A. Chalmers, Rajalakshmy Ayilam Ramachandran, Sayra J. Garcia, Evan Der, Leal Herlitz, Jeanette Ampudia, Dalena Chu, Nicole Jordan, Ting Zhang, Ioannis Parodis, Iva Gunnarsson, Huihua Ding, Nan Shen, Michelle Petri, Chi Chiu Mok, Ramesh Saxena, Krishna R. Polu, Stephen Connelly, Cherie T. Ng, Chandra Mohan, Chaim Putterman
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 1 (2022)
T cells are central to the pathogenesis of lupus nephritis (LN), a common complication of systemic lupus erythematosus (SLE). CD6 and its ligand, activated leukocyte cell adhesion molecule (ALCAM), are involved in T cell activation and trafficking. P
Externí odkaz:
https://doaj.org/article/5da04dc9777b4f09af0bd8b936c10fd9
Autor:
Samantha Stanley, Kamala Vanarsa, Samar Soliman, Deena Habazi, Claudia Pedroza, Gabriel Gidley, Ting Zhang, Shree Mohan, Evan Der, Hemant Suryawanshi, Thomas Tuschl, Jill Buyon, Chaim Putterman, Chi Chiu Mok, Michelle Petri, Ramesh Saxena, Chandra Mohan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Developing noninvasive diagnostic biomarkers for lupus nephritis (LN) diagnosis is an important clinical goal. Here the authors identify urinary proteins correlated with active LN and disease severity, which differ across ethnicities but collectively
Externí odkaz:
https://doaj.org/article/8f0c56b51da44a74acb2b59ce3524af9