Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ramesh Samineni"'
Autor:
Keerthana Balamurugan, Raghavender Medishetti, Jyothi Kotha, Parameshwar Behera, Kanika Chandra, Vijay Aditya Mavuduru, Manjunath B. Joshi, Ramesh Samineni, Madhumohan R. Katika, Writoban Basu Ball, Manjunatha Thondamal, Anil Challa, Kiranam Chatti, Kishore V.L. Parsa
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103766- (2022)
Summary: Infiltration of arterial intima by foamy macrophages is a hallmark of early atherosclerotic lesions. Here, we investigated the potential role of Ser/Thr phosphatase PHLPP1 in foam cell development. PHLPP1 levels were elevated in OxLDL-expose
Externí odkaz:
https://doaj.org/article/fe4f6b2971f64ef89092d79c791f559d
Autor:
Pranav Chintamani Joshi, Ramesh Samineni, Dwaipayan Bhattacharya, Bommana Raghunath Reddy, Lenin Veeraval, Tapatee Das, Swati Maitra, Abhipradnya Bipin Wahul, Shailaja Karri, Srihari Pabbaraja, Goverdhan Mehta, Arvind Kumar, Sumana Chakravarty
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Following our recent discovery of a new scaffold exhibiting significant neurotrophic and neurogenic activities, a structurally tweaked analogue, embodying a 2-oxa-spiro [5.4]decane framework, has been conceptualised and found to be more pote
Externí odkaz:
https://doaj.org/article/3b47189658eb4e4eb51a8e26cd13875c
Publikováno v:
ChemistrySelect. 7
Publikováno v:
Tetrahedron. 75:2923-2932
Aryne insertions into 1,3,5-tricarbonyl bearing dimethylacetonedicarboxylate (DMAD) proceeds through a 4-step cascade process to eventuate in a versatile one pot synthesis of functionally embellished naphthoresorcinols. Functional group amplification
Autor:
Bommana Raghunath Reddy, Swati Maitra, Lenin Veeraval, Srihari Pabbaraja, Dwaipayan Bhattacharya, Arvind Kumar, Tapatee Das, Ramesh Samineni, Goverdhan Mehta, Shailaja Karri, Sumana Chakravarty, Abhipradnya Bipin Wahul, Pranav Chintamani Joshi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Following our recent discovery of a new scaffold exhibiting significant neurotrophic and neurogenic activities, a structurally tweaked analogue, embodying a 2-oxa-spiro [5.4]decane framework, has been conceptualised and found to be more potent and ve
Publikováno v:
Organic letters. 21(9)
A new, one-pot domino benzannulation reaction between indole-3-ynones and various nitromethane derivatives has been explored for a general entry to diversely functionalized carbazole frameworks (28 examples). The scope of this new benzannulation has
Publikováno v:
Organic Letters. 18:6184-6187
An aryne insertion cascade reaction on oxindoles has been observed and constitutes a convenient "one pot" preparation of bioactive di- and triarylated oxindoles in good yields under mild conditions. A temperature controlled "reaction switch" enables
Publikováno v:
Angewandte Chemie (International ed. in English). 57(51)
A one-pot, transition-metal-free, domino Michael/SN Ar protocol of general applicability has been devised for the regioselective synthesis of polyfunctional naphthalenes by employing nitromethane and ortho-haloaryl ynones. Utilization of nitromethane
Publikováno v:
Organic letters. 19(22)
A general, transition-metal-free, one-pot, domino Michael–SNAr or AdNE substitution protocol was devised for spiroannulation of oxindoles with ortho-bromoaryl ynones, β-bromoalkenyl ynones, and β-bromoalkenyl enones in a convenient and efficient
Publikováno v:
Organic letters. 19(12)
A “product control via substrate design” strategy has been conceptualized and implemented to harness the potential of aryne and activated alkyne insertions into oxindoles to readily and efficiently furnish pharmacophoric indano- and cyclopentannu