Zobrazeno 1 - 10
of 355
pro vyhledávání: '"Ramesh R Bhonde"'
Autor:
Nidheesh Dadheech, Abhay Srivastava, Neha Paranjape, Shivika Gupta, Arpita Dave, Girish M Shah, Ramesh R Bhonde, Sarita Gupta
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128244 (2015)
Transplanting islets serves best option for restoring lost beta cell mass and function. Small bio-chemical agents do have the potential to generate new islets mass, however lack of understanding about mechanistic action of these small molecules event
Externí odkaz:
https://doaj.org/article/806c60840bbd447a8239b2ee38c16bff
Autor:
Soundarya L Madhira, Satya S Challa, Maniprabha Chalasani, Giridharan Nappanveethl, Ramesh R Bhonde, Rajanna Ajumeera, Vijayalakshmi Venkatesan
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48061 (2012)
BACKGROUND:Development of model systems have helped to a large extent, in bridging gap to understand the mechanism(s) of disease including diabetes. Interestingly, WNIN/GR-Ob rats (Mutants), established at National Centre for Laboratory Animals (NCLA
Externí odkaz:
https://doaj.org/article/1e48bf81254f47ae9832dcaa5f50fa4f
Autor:
Vikash Chandra, G Swetha, Sudhakar Muthyala, Amit K Jaiswal, Jayesh R Bellare, Prabha D Nair, Ramesh R Bhonde
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20615 (2011)
BACKGROUND: Type 1 Diabetes Mellitus is caused by auto immune destruction of insulin producing beta cells in the pancreas. Currently available treatments include transplantation of isolated islets from donor pancreas to the patient. However, this met
Externí odkaz:
https://doaj.org/article/2714a4dbb12b4e888df38ec14368b6fc
Publikováno v:
Current Diabetes Reviews. 19
Background: Diabetes Mellitus is defined by hyperglycemia, a condition which is the result of defects in insulin secretion, insulin action, or both. Evidence suggest that islet transplantation is a promising treatment approach, but the shortage of so
Autor:
Ramesh R. Bhonde, Supriya Kheur, Shankargouda Patil, Vishnu R Mani, Hosam Ali Baeshen, A. Thirumal Raj
Publikováno v:
Saudi Journal of Biological Sciences, Vol 28, Iss 11, Pp 6556-6567 (2021)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
Background The secretome of the dental pulp mesenchymal stem cells (DPMSCS-S) have an array of regenerative potential and could aid in the rehabilitation of cancer patients post-therapeutic interventions, although caution is required as DPMSC-S have
Autor:
Ramesh R. Bhonde, Bishnu K Khand
Publikováno v:
Current Stem Cell Research & Therapy. 16:231-237
Pluripotent Stem Cells [PSCs] are emerging as an excellent cellular source for the treatment of many degenerative diseases such as diabetes, ischemic heart failure, Alzheimer’s disease, etc. PSCderived pancreatic islet β-cells appear to be a promi
Autor:
Supriya Kheur, Sameena Parveen, Shankargouda Patil, Hosam Ali Baeshen, A. Thirumal Raj, Ramesh R. Bhonde, Nishant Vyas, Yaser Ali Alhazmi, Archana A. Gupta, Vikrant R Patil, Amit Jaisinghani, Ravindra V. Badhe
Publikováno v:
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 4, Pp 2210-2215 (2021)
Saudi Journal of Biological Sciences, Vol 28, Iss 4, Pp 2210-2215 (2021)
Vitamin D is a commonly used bone modulator in regenerative medicine. Several modalities have been explored for the delivery of vitamin D including nanoparticles and scaffold. The present study aimed to assess the potential use of a bio-degradable ch
Publikováno v:
Forum of Clinical Oncology, Vol 11, Iss 3, Pp 23-27 (2021)
Post-surgical recurrence and metastasis remain to be the major concern in oncology. The absence of any therapeutic modality during the interim period between the surgical intervention and initiation of conventional radiotherapy and chemotherapy allow
Publikováno v:
Chronic Diseases and Translational Medicine, Vol 7, Iss 1, Pp 47-56 (2021)
Chronic Diseases and Translational Medicine
Chronic Diseases and Translational Medicine
Background: Pharmacological factors used to induce insulin resistance (IR) in in vitro models may not mimic the full in vivo features of type 2 diabetes mellitus (T2DM). This study aimed to examine the ability of diabetic serum (DS) to induce IR and
Publikováno v:
Current Diabetes Reviews. 17:136-142
Diabetes is a chronic metabolic disorder of the endocrine system characterized by an increase in blood glucose level. Several factors, such as pancreatic damage, oxidative stress, infection, genetic factor, obesity, liver dysfunction, play a vital ro