Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Ramesh Periasamy"'
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 4, Pp 101331- (2024)
Age-related macular degeneration (AMD) affects millions of individuals worldwide and is a leading cause of blindness in the elderly. In dry AMD, lipoproteinaceous deposits called drusen accumulate between the retinal pigment epithelium (RPE) and Bruc
Externí odkaz:
https://doaj.org/article/0d75d8bb504a430e92b373b74252e46b
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285370 (2023)
Vascular endothelial cells (VEC) are essential for retinal homeostasis and their dysfunction underlies pathogenesis in diabetic retinopathy (DR) and exudative age-related macular degeneration (AMD). Studies have shown that recombinant adeno-associate
Externí odkaz:
https://doaj.org/article/414639d9a1454b6e8f76ccf60d3e82e0
Autor:
Sally L. Elshaer, William Evans, Mickey Pentecost, Raji Lenin, Ramesh Periasamy, Kumar Abhiram Jha, Shanta Alli, Jordy Gentry, Samuel M. Thomas, Nicolas Sohl, Rajashekhar Gangaraju
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-18 (2018)
Abstract Background Early-stage diabetic retinopathy (DR) is characterized by neurovascular defects. In this study, we hypothesized that human adipose-derived stem cells (ASCs) positive for the pericyte marker CD140b, or their secreted paracrine fact
Externí odkaz:
https://doaj.org/article/148f14b7819f4c0c998e70431459929e
Publikováno v:
Translational vision sciencetechnology. 11(8)
Retinal pericytes play a vital role in maintaining retinal homeostasis, and their dysfunction underlies pathogenesis in such vascular eye diseases as diabetic retinopathy and wet age-related macular degeneration. Consequently, retinal pericytes are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50dfb5e1a76c63aed505865008cb7a25
https://pubmed.ncbi.nlm.nih.gov/36018583
https://pubmed.ncbi.nlm.nih.gov/36018583
Autor:
Stefano Di Santo, Anna-Lena Fuchs, Ramesh Periasamy, Stefanie Seiler, Hans Rudolf Widmer Ph.D
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Endothelial progenitor cells (EPCs) promote revascularization and tissue repair mainly by paracrine actions. In the present study, we investigated whether EPC-secreted factors in the form of conditioned medium (EPC-CM) can protect cultured brain micr
Externí odkaz:
https://doaj.org/article/257a9753d9134c11bd597abcf1a42f79
Autor:
Bhubanananda Sahu, Laura Moreno Leon, Wei Zhang, Michael R. Volkert, Hemant Khanna, Nikita Puranik, Ramesh Periasamy
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Oxidative stress is a major factor underlying many neurodegenerative diseases. However, antioxidant therapy has had mixed results, possibly because of its indiscriminate activity. The purpose of our study was to determine if the human OXR1 (h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b0daa337f06b1e1011c2d5b04fb96b
https://pubmed.ncbi.nlm.nih.gov/34505865
https://pubmed.ncbi.nlm.nih.gov/34505865
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4876 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Diabetic retinopathy (DR), a complication of diabetes, is one of the leading causes of blindness in working-age adults. The pathology of the disease prevents the endogenous stem cells from participating in the natural repair of the diseased retina. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e0a3596b2e68411bd88c33cabae894
https://www.mdpi.com/1422-0067/20/19/4876
https://www.mdpi.com/1422-0067/20/19/4876
Publikováno v:
Regenerative engineering and translational medicine. 5(1)
Adipose-derived stem cells (ASCs) are multipotent mesenchymal progenitor cells that have functional and phenotypic overlap with pericytes lining microvessels in adipose tissue. The role of CD140b [platelet-derived growth factor receptor- β (PDGFR-β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7fa29315da8ebedc5ceaf1d53edf3b
https://pubmed.ncbi.nlm.nih.gov/30976657
https://pubmed.ncbi.nlm.nih.gov/30976657
Publikováno v:
Regenerative Engineering and Translational Medicine. 6:114-114
An affiliation for Dr. Sally L. Elshaer was inadvertently omitted from this paper: Department of Pharmacology and Toxicology, College of Pharmacy, Mansoura University, 60 Elgomhoria St, Mansoura, 35516, Egypt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fb6e55c98a111c8f4da560d27ffe4d2
https://doi.org/10.1007/s40883-020-00152-4
https://doi.org/10.1007/s40883-020-00152-4
Publikováno v:
Regenerative Medicine-from Protocol to Patient ISBN: 9783319282916
Studies conducted in animal models and human tissues have suggested that retinopathies occur through loss of cells resulting in vascular leakage, excessive immature retinal angiogenesis, and neuronal degeneration eventually leading to loss of vision.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ae13fe8bec4b233af4b8ac3c6d6ca53
https://doi.org/10.1007/978-3-319-28293-0_9
https://doi.org/10.1007/978-3-319-28293-0_9
