Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Ramesh Panchagnula"'
Publikováno v:
Arzneimittelforschung. 55:198-204
The transdermal route provides an attractive alternative to the presently used peroral therapy with tricyclic antidepressants due to the avoidance of first-pass metabolism and the associated side effects. In this investigation an earlier developed tr
Autor:
V. Bhardwaj, Ramesh Panchagnula
Publikováno v:
Drug Development and Industrial Pharmacy. 34:642-649
Rifampicin, one of the main first line anti-TB drugs, shows variable bioavailability in different marketed preparations and reasons cited include physiological, degradation, manufacturing/ processing, solid state, and bioavailability assessment proce
Autor:
Manthena V.S. Varma, Gunjan Kohli, Kanwal Jit Kaur, Singh I, Shrutidevi Agrawal, Shantaram R Bhade, Yasvanth Ashokraj, Ramesh Panchagnula
Publikováno v:
Clinical Research and Regulatory Affairs. 25:1-12
The current recommended treatment for tuberculosis (TB) is a cocktail of anti-TB drugs, preferably in fixed dose combinations (FDC). Rifampicin, one of the important anti-TB drugs, was reported to exhibit variable bioavailability and is classified as
Publikováno v:
Clinical Research and Regulatory Affairs. 24:61-76
The purpose of this investigation was to develop the dissolution methodology for evaluation of rifampicin-containing fixed-dose combinations of antituberculosis (anti-TB) drugs using BCS-based approach. In this investigation, dissolution studies were
Publikováno v:
Analytica Chimica Acta. 570:41-45
An accurate, sensitive and specific reversed phase high performance liquid chromatographic method (RP-HPLC) for the simultaneous quantitative determination of the nucleoside reverse transcriptase inhibitors lamivudine, stavudine with the non-nucleosi
Autor:
Singh I, Kaur Kj, Shantaram Ramdos Bade, Jitendra Parmar, Ramesh Panchagnula, Yasvanth Ashokraj
Publikováno v:
International Journal of Pharmaceutics. 313:5-13
Tuberculosis is one of the microbial diseases having a long history of its occurrence and yet to be eradicated from the world. Due to the development of bacterial resistance, treatment has changed from monotherapy to combotherapy to fixed dose combin
Publikováno v:
Clinical Research and Regulatory Affairs. 23:53-70
The use of fixed dose combinations (FDCs) of anti-TB (Tuberculosis) drugs is recommended by World Health Organization (WHO) and International Union Against Tuberculosis and Lung Disease (IUATLD) to ensure proper treatment of tuberculosis. FDCs have t
Publikováno v:
Clinical Research and Regulatory Affairs. 23:71-83
The objective of this investigation was to study the effect of contact of rifampicin physical form with the dissolution medium. Solid-state characterization of the residues obtained from powder dissolution studies were conducted and found that rifamp
Publikováno v:
Journal of Pharmaceutical Sciences. 94:2632-2643
The purpose of this investigation is to evaluate the quantitative contribution of pH-dependent passive permeability on the functional activity of P-glycoprotein (P-gp) in limiting intestinal absorption of weakly basic drugs, in order to include this
Autor:
Neeraj Kumar, Alf Lamprecht, V. Bhardwaj, Ramesh Panchagnula, I. Bala, M. N. V. Ravi Kumar, S. Hariharan
Publikováno v:
Journal of Biomedical Nanotechnology. 1:235-258