Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Ramesh P Thylur"'
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Akademický článek
Assessment of risk factors, and racial and ethnic differences in hepatocellular carcinoma
Autor: Ramesh P Thylur, Sanjit K Roy, Anju Shrivastava, Thomas A LaVeist, Sharmila Shankar, Rakesh K Srivastava
Publikováno v: JGH Open, Vol 4, Iss 3, Pp 351-359 (2020)
Abstract Despite improved screening and surveillance guidelines, significant race/ethnicity‐specific disparities in hepatocellular carcinoma (HCC) continue to exist and disproportionately affect minority and disadvantaged populations. This trend in
Externí odkaz: https://doaj.org/article/aa598d78732341ba9e36cc241dc9627b
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2
IL-4 Treatment Mitigates Experimental Cerebral Malaria by Reducing Parasitemia, Dampening Inflammation, and Lessening the Cytotoxicity of T Cells
Autor: Ramesh P. Thylur, D. Channe Gowda, Christopher C. Norbury, Kishore Punnath, Kiran K. Dayanand, Xianzhu Wu
Publikováno v: The Journal of Immunology. 206:118-131
Cytokine responses to malaria play important roles in both protective immunity development and pathogenesis. Although the roles of cytokines such as TNF-α, IL-12, IFN-γ, and IL-10 in immunity and pathogenesis to the blood stage malaria are largely
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2d69d08274f15ff25e60c0413a954a
https://doi.org/10.4049/jimmunol.2000779
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3
Assessment of risk factors, and racial and ethnic differences in hepatocellular carcinoma
Autor: Sharmila Shankar, Rakesh K. Srivastava, Ramesh P. Thylur, Thomas A. LaVeist, Sanjit K. Roy, Anju Shrivastava
Publikováno v: JGH Open, Vol 4, Iss 3, Pp 351-359 (2020)
JGH Open: An Open Access Journal of Gastroenterology and Hepatology
Despite improved screening and surveillance guidelines, significant race/ethnicity‐specific disparities in hepatocellular carcinoma (HCC) continue to exist and disproportionately affect minority and disadvantaged populations. This trend indicates t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3fb679f906d1e4cccf3c173dc73a5b
https://doaj.org/article/aa598d78732341ba9e36cc241dc9627b
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5
Small molecule–based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes
Autor: Kiran K. Dayanand, D. Channe Gowda, Xianzhu Wu, Christopher C. Norbury, Ramesh P. Thylur
Publikováno v: Journal of Biological Chemistry. 292:13615-13634
Malaria infections cause several systemic and severe single- or multi-organ pathologies, killing hundreds of thousands of people annually. Considering the existing widespread resistance of malaria parasites to anti-parasitic drugs and their high prop
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf9a51414b12bd794edf184ef4e0475
https://doi.org/10.1074/jbc.m116.770313
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6
CD36 receptor regulates malaria-induced immune responses primarily at early blood stage infection contributing to parasitemia control and resistance to mortality
Autor: Kishore Punnath, D. Channe Gowda, Ramesh P. Thylur, Xianzhu Wu, Nagaraj M. Gowda, Maria Febbraio, Shivayogeeshwara E. Neelgund
Publikováno v: Journal of Biological Chemistry. 292:9394-9408
In malaria, CD36 plays several roles, including mediating parasite sequestration to host organs, phagocytic clearance of parasites, and regulation of immunity. Although the functions of CD36 in parasite sequestration and phagocytosis have been clearl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f358e2e7b8ee09a6277c11c4cafaef1
https://doi.org/10.1074/jbc.m117.781294
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7
Conserved Noncoding Sequences Boost ADR1 and SP1 Regulated Human Swiprosin-1 Promoter Activity
Autor: Young-Min Hyun, Chang-Duk Jun, Ramesh P. Thylur, Sung Yong Ahn, Eunhea Jung
Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Swiprosin-1 is expressed in various types of cells or tissues of different species. To investigate the mechanisms underlying Swiprosin-1 expression pattern, we analyzed the promoter activity of 2-kilobase genomic sequences located at 5′ flanking re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363c3f666200827cf6f39901212909ef
https://pubmed.ncbi.nlm.nih.gov/30405162
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9
Swiprosin-1 is expressed in mast cells and up-regulated through the protein kinase CβI/η pathway
Autor: Chang-Duk Jun, Ho Keun Kwon, Zee-Yong Park, Sin-Hyeog Im, Ramesh P. Thylur, Young Dae Kim, Min-Sung Kwon, Sang-Hyun Kim, Hyun-Mee Oh, Jang-Soo Chun
Publikováno v: Journal of Cellular Biochemistry. 108:705-715
Swiprosin-1 exhibits the highest expression in CD8 þ T cells and immature B cells and has been thought to play a role in lymphocyte physiology. Here we report that swiprosin-1 is also expressed in mast cells and up-regulated in both in vitro culture
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6530883f79c12c7299df3a653d3ccc
https://doi.org/10.1002/jcb.22307
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10
ERK Signaling-regulated Immune Responses that contributes to Malaria Parasitemia and Pathogenesis
Autor: Xianzhu Wu, Kiran K. Dayanand, Ramesh P Thylur, Christopher C Norbury, Channe Gowda
Publikováno v: The Journal of Immunology. 198:77.1-77.1
Malaria morbidity and mortality represent a major health and social burdens in many countries around the globe. Given that malaria parasites are becoming more and more refractory to several commonly used drugs, a vaccine is needed to control malaria.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0436c4d56a74a390a08eefee885a75af
https://doi.org/10.4049/jimmunol.198.supp.77.1
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