Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ramesh K. Sood"'
Autor:
Brent E. Korba, Ramachandra S. Hosmane, Earl R. Kern, Ramesh K. Sood, Ali Fattom, Vishweshwar S. Bhadti, Robert B. Naso, Huan-Ming Chen
Publikováno v:
Antiviral Research. 53:159-164
Novel ring-expanded nucleoside (REN) analogs (1-3) containing 5:7 fused ring systems as the heterocyclic base were found to be potent and selective inhibitors of hepatitis B virus (HBV) replication in cultured human hepatoblastoma 2.2.15 cells. The m
Publikováno v:
Nucleosides and Nucleotides. 18:331-335
An efficient, short synthesis of a ring-expanded nucleoside analogue containing a novel 5:7-fused, planar, and potentially aromatic imidazo[4,5-e][1,3]diazepine heterocyclic ring system is reported. The target compound, 6-amino-8-hydroxy-4H-1-beta-D-
Publikováno v:
Infection and Immunity. 66:2441-2446
A simple and convenient method was developed for the preparation of Streptococcus pneumoniae type 14 polysaccharide (Pn14PS)-tetanus toxoid (TT) conjugate vaccines, using terminally linked Pn14PS fragments of different lengths. Native Pn14PS was simu
Autor:
Ali Ibrahim Fattom, Ramesh K. Sood
Publikováno v:
Expert Opinion on Investigational Drugs. 7:333-347
Capsular polysaccharides (CPs), present on the surface of most pathogenic bacteria, have been recognised as virulence factors. Antibodies specific to these polysaccharides can mediate the killing of these bacteria by phagocytes in the presence of com
Publikováno v:
Drug Discovery Today. 1:381-387
The conjugation of polysaccharides to carrier proteins generally enhances polysaccharide immunogenicity and renders the immune response T-cell dependent. Such enhancement of immunogenicity has made the use of conjugate vaccines possible in population
Publikováno v:
Canadian Journal of Chemistry. 72:237-246
An exploration of the synthesis of D-glycero-D-altro-heptose, a constitutent of O antigen chains in lipopolysaccharides from Campylobacter jejuni serotypes O:23 and O:36 led to a study of the 2-trimethylsilylthiazole homologation procedure for heptos
Publikováno v:
Canadian Journal of Chemistry. 72:247-251
Methyl α-D-glycopyranosides of 6-deoxy-D-altro-heptose, 6-deoxy-D-manno-heptose, and 6-deoxy-D-talo-heptose have been prepared. Displacements of methyl 2,3,4-tri-O-benzylhexopyranoside 6-trifluoromethanesulfonates with potassium cyanide, followed by
Publikováno v:
ChemInform. 25
Methyl α-D-glycopyranosides of 6-deoxy-D-altro-heptose, 6-deoxy-D-manno-heptose, and 6-deoxy-D-talo-heptose have been prepared. Displacements of methyl 2,3,4-tri-O-benzylhexopyranoside 6-trifluoromethanesulfonates with potassium cyanide, followed by
Publikováno v:
ChemInform. 25
An exploration of the synthesis of D-glycero-D-altro-heptose, a constitutent of O antigen chains in lipopolysaccharides from Campylobacter jejuni serotypes O:23 and O:36 led to a study of the 2-tri...
Publikováno v:
ChemInform. 30
An efficient, short synthesis of a ring-expanded nucleoside analogue containing a novel 5:7-fused, planar, and potentially aromatic imidazo[4,5-e][1,3]diazepine heterocyclic ring system is reported. The target compound, 6-amino-8-hydroxy-4H-1-β-D-ri