Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Ramesh J. Kurukulaaratchy"'
Autor:
Anna T. Freeman, David Hill, Colin Newell, Helen Moyses, Adnan Azim, Deborah Knight, Laura Presland, Matthew Harvey, Hans Michael Haitchi, Alastair Watson, Karl J. Staples, Ramesh J. Kurukulaaratchy, Tom M. A. Wilkinson
Publikováno v:
Asthma Research and Practice, Vol 6, Iss 1, Pp 1-11 (2020)
Abstract Background Exercise is recommended in guidelines for asthma management and has beneficial effects on symptom control, inflammation and lung function in patients with sub-optimally controlled asthma. Despite this, physical activity levels in
Externí odkaz:
https://doaj.org/article/e3f249f3857647de998b59a98b75270c
Autor:
Mohammed A. Kyyaly, Tilman Sanchez‐Elsner, Peijun He, Collin L. Sones, S. Hasan Arshad, Ramesh J. Kurukulaaratchy
Publikováno v:
Clinical and Translational Allergy, Vol 11, Iss 4, Pp n/a-n/a (2021)
Abstract Background Identifying patients at risk of severe asthma is vitally important given the disproportionate burden of disease imposed by that state. However, biomarkers to support such needs remain elusive. Methods In this letter, we assessed w
Externí odkaz:
https://doaj.org/article/6abaf028ae6746e5915372ccf070cdaa
Autor:
Adnan Azim, Heena Mistry, Anna Freeman, Clair Barber, Colin Newell, Kerry Gove, Yvette Thirlwall, Matt Harvey, Kimberley Bentley, Deborah Knight, Karen Long, Frances Mitchell, Yueqing Cheng, Judit Varkonyi-Sepp, Wolfgang Grabau, Paddy Dennison, Hans Michael Haitchi, S. Hasan Arshad, Ratko Djukanovic, Tom Wilkinson, Peter Howarth, Ramesh J. Kurukulaaratchy
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Asthma is now widely recognised to be a heterogeneous disease. The last two decades have seen the identification of a number of biological targets and development of various novel therapies. Despite this, asthma still represents a
Externí odkaz:
https://doaj.org/article/6f0e734243314ef0a96b91c6660ed495
Autor:
Wilfried Karmaus, Nandini Mukherjee, Vimala Devi Janjanam, Su Chen, Hongmei Zhang, Graham Roberts, Ramesh J. Kurukulaaratchy, Hasan Arshad
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Pre-bronchodilator lung function including forced vital capacity (FVC), forced expiratory flow in 1 second (FEV1), their ratio (FEV1/FVC), and forced expiratory flow 25–75% (FEF25–75) measured at age 10, 18, and 26 years in the Isle of W
Externí odkaz:
https://doaj.org/article/a4cba0afa76f42f2ae11cc6db942cda3
Autor:
Ali H. Ziyab, Nandini Mukherjee, Ramesh J. Kurukulaaratchy, Hongmei Zhang, Susan Ewart, Hasan Arshad, Wilfried Karmaus
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-9 (2018)
Abstract Background Epidemiologic studies have demonstrated associations between acetaminophen use and asthma. This investigation sought to determine whether sex modifies the acetaminophen-asthma association and whether leptin (LEP) and leptin recept
Externí odkaz:
https://doaj.org/article/34ece525cdc3439199a1637771993822
Autor:
Hitasha Rupani, Mohammed Aref Kyyaly, Adnan Azim, Rana Abadalkareen, Anna Freeman, Paddy Dennison, Peter Howarth, Ratko Djukanovic, Pandurangan Vijayanand, Gregory Seumois, S Hasan Arshad, Hans Michael Haitchi, Ramesh J. Kurukulaaratchy
Background: asthma is conventionally stratified as type 2-inflammation (T2) high or T2-low disease. Identifying T2-status has therapeutic implications for patient management but real-world understanding of this T2 paradigm in difficult-to-treat/ seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0235460390491a0e05a568e1a9a71cbe
https://eprints.soton.ac.uk/477586/
https://eprints.soton.ac.uk/477586/
Autor:
Adnan Azim, Faisal I. Rezwan, Clair Barber, Matthew Harvey, Ramesh J. Kurukulaaratchy, John W. Holloway, Peter H. Howarth
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 10; Pages: 1635
The measurement of exhaled volatile organic compounds (VOCs) in exhaled breath (breathomics) represents an exciting biomarker matrix for airways disease, with early research indicating a sensitivity to airway inflammation. One of the key aspects to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abad4e6a12d18ae3a8fdfa0005d6f15
https://eprints.soton.ac.uk/472170/
https://eprints.soton.ac.uk/472170/
Difficult-to-treat (or difficult) asthma presents a challenging multidimensional model of chronic disease that imposes a significant burden at both individual patient and wider societal levels. Within that model of disease there is increasing underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd0e20a6f604fd9d1bbd8a25c65657a6
https://doi.org/10.26493/978-961-293-157-5.45-65
https://doi.org/10.26493/978-961-293-157-5.45-65
Autor:
Wei Chern Gavin Fong, Ishmail Rafiq, Matthew Harvey, Sabina Stanescu, Ben Ainsworth, Judit Varkonyi-Sepp, Heena Mistry, Mohammed Aref Kyyaly, Clair Barber, Anna Freeman, Tom Wilkinson, Ratko Djukanovic, Paddy Dennison, Hans Michael Haitchi, Ramesh J. Kurukulaaratchy
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 5; Pages: 686
Difficult asthma describes asthma in which comorbidities, inadequate treatment, suboptimal inhaler technique and/or poor adherence impede good asthma control. The association of anxiety and depression with difficult asthma outcomes (exacerbations, ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b5cb2970c3ae11c4c2b754b1e1e8bc
Publikováno v:
ERJ Open Research, Vol 2, Iss 3 (2016)
Up to 10% of asthmatics have “difficult asthma”; however, they account for 80% of asthma-related expenditure and run the highest risk of acute severe exacerbations. An estimated 75% of admissions for asthma are avoidable. Guidelines advise that t
Externí odkaz:
https://doaj.org/article/6c4deb808c5c42a994b0cb0fefbd4ba6