Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ramesh C Kovi"'
Autor:
Ashley M Brooks, Andrea Vornoli, Ramesh C Kovi, Thai Vu T Ton, Miaofei Xu, Ahmed Mashal, Eva Tibaldi, Federica Gnudi, Jian-Liang Li, Robert C Sills, John R Bucher, Daniele Mandrioli, Fiorella Belpoggi, Arun R Pandiri
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0296699 (2024)
The cancer hazard associated with lifetime exposure to radiofrequency radiation (RFR) was examined in Sprague Dawley (SD) rats at the Ramazzini Institute (RI), Italy. There were increased incidences of gliomas and cardiac schwannomas. The translation
Externí odkaz:
https://doaj.org/article/b685aa37cc7a40f4be53d0cfd6f31d19
Autor:
Kelly A. Fader, Ingrid D. Pardo, Ramesh C. Kovi, Christopher J. Somps, Helen Hong Wang, Vishal S. Vaidya, Shashi K. Ramaiah, Madhu P. Sirivelu
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 264-277 (2022)
Adeno-associated virus (AAV)-induced dorsal root ganglia (DRG) toxicity has been observed in several nonclinical species, where lesions are characterized by neuronal degeneration/necrosis, nerve fiber degeneration, and mononuclear cell infiltration.
Externí odkaz:
https://doaj.org/article/86125310200649c0a9c68fcd0e3733f4
Autor:
Claudia Huichalaf, Tyler L. Perfitt, Anna Kuperman, Renea Gooch, Ramesh C. Kovi, Karrie A. Brenneman, Xian Chen, Dinesh Hirenallur-Shanthappa, Tiffany Ma, Basel T. Assaf, Ingrid Pardo, Tania Franks, Laura Monarski, Ting-Wen Cheng, Kevin Le, Chunyan Su, Suryanarayan Somanathan, Laurence O. Whiteley, Christine Bulawa, Marko J. Pregel, Alain Martelli
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 367-378 (2022)
Friedreich's ataxia is a rare disorder resulting from deficiency of frataxin, a mitochondrial protein implicated in the synthesis of iron-sulfur clusters. Preclinical studies in mice have shown that gene therapy is a promising approach to treat indiv
Externí odkaz:
https://doaj.org/article/46b5bb7ac72846398fc35f753653a2fa
Autor:
Mark J. Hoenerhoff, Keith R. Shockley, Ramesh C Kovi, Ronald Herbert, Raveena M Chhabria, Mamta Behl, Kevin Gerrish, Robert C. Sills, Arun R. Pandiri, Thai-Vu Ton, Teja N Peddada, Norris D Flagler
Publikováno v:
Arch Toxicol
Rodent alveolar/bronchiolar carcinomas (ABC) that arise either spontaneously or due to chemical exposure are similar to a subtype of lung adenocarcinomas in humans. B6C3F1/N mice and F344/NTac rats exposed to cobalt metal dust (CMD) by inhalation dev
Autor:
Thai-Vu T. Ton, Hue-Hua L. Hong, Ramesh C. Kovi, Keith R. Shockley, Shyamal D. Peddada, Kevin E. Gerrish, Kyathanahalli S. Janardhan, Gordon Flake, Mathew D. Stout, Robert C. Sills, Arun R. Pandiri
Publikováno v:
Toxicologic Pathology. :019262332311573
Antimony trioxide (AT) is used as a flame retardant in fabrics and plastics. Occupational exposure in miners and smelters is mainly through inhalation and dermal contact. Chronic inhalation exposure to AT particulates in B6C3F1/N mice and Wistar Han
Autor:
Jochen Woicke, Muthafar M. Al-Haddawi, Jean-Guy Bienvenu, Jessica M. Caverly Rae, Franck J. Chanut, Karyn Colman, John M. Cullen, Wendell Davis, Ryo Fukuda, Maike Huisinga, Ursula Junker Walker, Kiyonori Kai, Ramesh C. Kovi, Nicholas P. Macri, Heike-Antje Marxfeld, Kristen J. Nikula, Ingrid D. Pardo, Thomas J. Rosol, Alok K. Sharma, Bhanu P. Singh, Kazutoshi Tamura, Michael S. Thibodeau, Enrico Vezzali, Justin D. Vidal, Emily K. Meseck
Publikováno v:
Toxicologic Pathology. 49:5-109
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions) Project ( www.toxpath.org/inhand.asp ) is a joint initiative of the societies of toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP)
Autor:
Alys Bradley, Ramesh C. Kovi, Wolfgang Kaufmann, Deepa B. Rao, Mark T. Butt, Alok K. Sharma, Sibylle Gröters, Robert C. Sills, Robert H. Garman, Brad Bolon, Peter B Little, Sarah D Cramer, Makoto Shibutani, Catherine George, Stephanie Czasch, Georg Krinke, Isao Narama
Publikováno v:
Toxicologic Pathology. 48:827-844
Harmonization of diagnostic terminology used during the histopathologic analysis of rodent tissue sections from nonclinical toxicity studies will improve the consistency of data sets produced by laboratories located around the world. The INHAND Proje
Autor:
Kelly A. Fader, Ingrid D. Pardo, Ramesh C. Kovi, Christopher J. Somps, Helen Hong Wang, Vishal S. Vaidya, Shashi K. Ramaiah, Madhu P. Sirivelu
Adeno-associated virus (AAV)-induced dorsal root ganglia (DRG) toxicity has been observed in several nonclinical species, where lesions are characterized by neuronal degeneration/necrosis, nerve fiber degeneration, and mononuclear cell infiltration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3887d189c54e6f093f86109ff2fb660f
https://doi.org/10.1101/2021.12.23.473896
https://doi.org/10.1101/2021.12.23.473896
Autor:
Arun R. Pandiri, Cynthia V. Rider, Kevin Gerrish, Ramesh C. Kovi, Sailesh Surapureddi, Robert C. Sills, Sachin Bhusari, Jian-Liang Li, Shyamal D. Peddada, Haruhiro Yamashita, Mark J. Hoenerhoff, Keith R. Shockley, Thai Vu T. Ton
Publikováno v:
Arch Toxicol
Ginkgo biloba extract (GBE) is used in traditional Chinese medicine as an herbal supplement for improving memory. Exposure of B6C3F1/N mice to GBE in a 2-year National Toxicology Program (NTP) bioassay resulted in a dose-dependent increase in hepatoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5abd71f451e8e8223b77dc26fcec558a
https://europepmc.org/articles/PMC8077180/
https://europepmc.org/articles/PMC8077180/
Autor:
Kristin Groenvold, Ramesh C. Kovi, Cert. Zoo, Sarah M. Churgin, Paolo R. Martelli, Foo Khong Lee, Kam Yan Cheung
Publikováno v:
Journal of Zoo and Wildlife Medicine. 49:470-474
Two adult sibling red-handed tamarins (Saguinus midas) presented with weight loss and multifocal skin masses. A skin biopsy revealed pyogranulomatous dermatitis with intrafollicular Demodex sp. mites. Subsequent skin scrapes confirmed the presence of