Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ramesh Baliga"'
Autor:
Angus Sinclair, Thierry Giffon, Dean Ng, Poonam Yakkundi, Hope Lancero, Marigold Manlusoc, Rodnie Rosete, Avneesh Saini, Madeline Tran, Kevin Carlin, Chitra Saraiya, Ramesh Baliga, Bruce Keyt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/f409f288839b4ef28aeb52ed133e3d6e
Autor:
Gang Yin, Heather T. Stephenson, Junhao Yang, Xiaofan Li, Stephanie M. Armstrong, Tyler H. Heibeck, Cuong Tran, Mary Rose Masikat, Sihong Zhou, Ryan L. Stafford, Alice Y. Yam, John Lee, Alexander R. Steiner, Avinash Gill, Kalyani Penta, Sonia Pollitt, Ramesh Baliga, Christopher J. Murray, Christopher D. Thanos, Leslie M. McEvoy, Aaron K. Sato, Trevor J. Hallam
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Amber codon suppression for the insertion of non-natural amino acids (nnAAs) is limited by competition with release factor 1 (RF1). Here we describe the genome engineering of a RF1 mutant strain that enhances suppression efficiency during ce
Externí odkaz:
https://doaj.org/article/847eaf6ce18d47c0aa91ced7f6902fb0
Publikováno v:
Antibodies, Vol 9, Iss 4, p 53 (2020)
Natural immunoglobulin M (IgM) antibodies are pentameric or hexameric macro-immunoglobulins and have been highly conserved during evolution. IgMs are initially expressed during B cell ontogeny and are the first antibodies secreted following exposure
Externí odkaz:
https://doaj.org/article/07d7cd4f3fa94a508c39b3bdd6743fd8
Autor:
Rodnie Rosete, Poonam Yakkundi, Bruce Keyt, Thierry Giffon, Kevin Carlin, Ramesh Baliga, Dean Ng, Avneesh Saini, Hope Lancero, Marigold Manlusoc, Angus M. Sinclair, Madeline Tran, Chitra Saraiya
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Therapeutic antibodies inhibiting PD-1/PD-L1 have demonstrated clinical efficacy though only a fraction of patients respond. Combinations are being explored to enhance responses including anti-PD-1/PD-L1 IgG antibodies with IL-15-pathway s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4f8b37bb95a76cd07f0a66a501c3b5
https://doi.org/10.1136/jitc-2020-sitc2020.0569
https://doi.org/10.1136/jitc-2020-sitc2020.0569
Publikováno v:
Antibodies, Vol 9, Iss 53, p 53 (2020)
Antibodies
Antibodies
Natural immunoglobulin M (IgM) antibodies are pentameric or hexameric macro-immunoglobulins and have been highly conserved during evolution. IgMs are initially expressed during B cell ontogeny and are the first antibodies secreted following exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ecd5a2c4aff80967422e4fb3275f6f
https://www.mdpi.com/2073-4468/9/4/53
https://www.mdpi.com/2073-4468/9/4/53
Autor:
Alexander Steiner, Gang Yin, John K. Lee, Ramesh Baliga, Christopher J. Murray, Avinash Gill, Cuong D. Tran, Alice Yam, Junhao Yang, Sihong Zhou, Trevor J. Hallam, Sonia Pollitt, Christopher D. Thanos, Xiaofan Li, Stephanie Armstrong, Tyler H. Heibeck, Kalyani Penta, Ryan Stafford, Leslie Mcevoy, Aaron K. Sato, Heather Stephenson, Mary Rose Masikat
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Amber codon suppression for the insertion of non-natural amino acids (nnAAs) is limited by competition with release factor 1 (RF1). Here we describe the genome engineering of a RF1 mutant strain that enhances suppression efficiency during cell-free p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd39483da24bc04be82d0c3cd7590da8
https://doaj.org/article/847eaf6ce18d47c0aa91ced7f6902fb0
https://doaj.org/article/847eaf6ce18d47c0aa91ced7f6902fb0
Autor:
Paul Hinton, Bruce Keyt, Daniel S. Chen, Madeline H. Tran, Chitra Saraiya, Ramesh Baliga, Stephen F. Carroll, Dean C. Ng, Marigold Manlusoc, Hai Lu, Yuan C. Cao, Sachi Rahman, Bing Shan, Marvin Peterson, Keyu Li, Avneesh Saini
Publikováno v:
Cancer Research. 80:5664-5664
We have developed a novel T cell engaging bispecific antibody platform that utilizes the high avidity of IgM antibodies, but further combines this with the high affinity and specificity of IgG antibodies. By grafting the affinity matured binding doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dec4ac4d1533b85b287cbaafcb38305
https://doi.org/10.1158/1538-7445.am2020-5664
https://doi.org/10.1158/1538-7445.am2020-5664
Autor:
Beatrice Wang, Bing Shan, Bruce Keyt, Ramesh Baliga, Tasnim Kothambawala, Ling Wang, Angus M. Sinclair, Hai Lu, Marvin Peterson
Publikováno v:
Cancer Research. 80:518-518
Death receptor 5 (DR5) is a member of the tumor necrosis factor (TNF) receptor superfamily that binds TNF-related apoptosis inducing ligand (TRAIL) to induce receptor trimerization and activate extrinsic apoptotic pathways. DR5 is expressed on a broa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a91452b58d6eec8cd9569b0c4760b54
https://doi.org/10.1158/1538-7445.am2020-518
https://doi.org/10.1158/1538-7445.am2020-518
Autor:
Bruce Keyt, Chitra Saraiya, Dean Ng, Ramesh Baliga, Steve Carroll, Avneesh Saini, Paul Hinton, Sachi Rahman, Keyu Li, Madeline Tran, Bing Shan, Marigold Manlusoc, Hai Lu, Marvin Peterson, Yuan Cao, Wayne R. Godfrey
Publikováno v:
Journal of Clinical Oncology. 38:e15007-e15007
e15007 Background: Bispecific antibodies which tether T-cells to cancer cells, and additionally activate T-cell mediated killing, have shown promise in treating B-cell malignancies. Dose intensity, however, is limited by cytokine release from the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c16915fffcd12570d1b4a753f489c2e6
https://doi.org/10.1200/jco.2020.38.15_suppl.e15007
https://doi.org/10.1200/jco.2020.38.15_suppl.e15007
Autor:
Juan Jose Fung, Ryan Stafford, Gang Yin, Chris Murray, Xiaofan Li, Marissa L. Matsumoto, Alex Steiner, Ramesh Baliga, Trevor J. Hallam, Heather Stephenson, Qi Cai, Christopher D. Thanos, Willie D. Wang, Mary Rose Masikat, Monica You, Avinash Gill, Aaron K. Sato, Shwu-Hwa Lin, Kalyani Penta
Publikováno v:
Protein Engineering, Design and Selection
Selection technologies such as ribosome display enable the rapid discovery of novel antibody fragments entirely in vitro. It has been assumed that the open nature of the cell-free reactions used in these technologies limits selections to single-chain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60af782707d4cb2bc70aeb4f30e0a1c
https://doi.org/10.1093/protein/gzu002
https://doi.org/10.1093/protein/gzu002