Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ramesh B. Bambal"'
Autor:
Tridib Chaira, Kunihiko Fujii, Tarani Kanta Barman, Vattan Joshi, Dilip J. Upadhyay, Ram Kumar, Lalima Sharma, Manoj Kumar, Mahadev Bandgar, Pradip Kumar Bhatnagar, Ramesh B. Bambal, Ashwani Kumar Verma, Tarun Mathur, Manisha Pandya, Nobuhisa Masuda, Balasaheb Gangadhar Jadhav
Publikováno v:
The Journal of antimicrobial chemotherapy. 76(11)
Objectives FtsZ is an essential bacterial protein and an unexplored target for the development of antibacterial drugs. The development of a novel inhibitor targeting FtsZ offers a potential opportunity to combat drug resistance. DS01750413, a new der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912a6020dd58ba659bbe4ecfad9470f3
https://pubmed.ncbi.nlm.nih.gov/34383913
https://pubmed.ncbi.nlm.nih.gov/34383913
Autor:
Jitendra A. Sattigeri, Ramesh B. Bambal, Takahide Nishi, Ajay Soni, Pragya Bhateja, Tarun Jain, Dilip J. Upadhyay, Nidhi Alekar, Tridib Chaira, Abdul Rehman Abdul Rauf, Mahesh Subhashrao Deshmukh, Malvika Garg, Tarani Kanta Barman, Mahendrakumar Gupta, Paras Kumar Jha
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:2993-2997
FimH is a type I fimbrial lectin located at the tip of type-1 pili of Gram-negative uropathogenic Escherichia coli (UPEC) guiding its ability to adhere and infect urothelial cells. Accordingly, blocking FimH with small molecule inhibitor is considere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3bc6bdb4dacfe527179ac7c4c34b32
https://doi.org/10.1016/j.bmcl.2018.06.017
https://doi.org/10.1016/j.bmcl.2018.06.017
Autor:
Ramesh B. Bambal, Alka Khanna, Indu Pal Kaur, Mandeep Singh, Ruchi Sood, Pradip Kumar Bhatnagar, Tridib Chaira, Harinder Singh, Dilip J Upadhaya
Publikováno v:
Current drug delivery. 17(4)
Background: Rifampicin is known to degrade at the acidic pH of the stomach, especially in the presence of isoniazid. Although isoniazid also degrades partially, its degradation is reversible. Objective: Presently, we provide a proof of the fact that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dae8f0ddeac0de38180b40cbe53dff0
https://pubmed.ncbi.nlm.nih.gov/32077827
https://pubmed.ncbi.nlm.nih.gov/32077827
Autor:
Nobuhisa Masuda, Amuliya Kashyap, Madhvi Rao, Ramesh B. Bambal, Manoj Kumar, Tarani Kanta Barman, Vattan Joshi, Tridib Chaira, Kedar Purnapatre, Dilip J. Upadhyay, Souhaila Al Khodor, Manisha Pandya
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
DS86760016 is a new leucyl-tRNA-synthetase inhibitor at the preclinical development stage. DS86760016 showed potent activity against extended-spectrum multidrug-resistant Pseudomonas aeruginosa isolated from clinical samples and in vitro biofilms. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d7ee783cec25dbe4f28eee80bf3cda
https://doi.org/10.1128/aac.02122-18
https://doi.org/10.1128/aac.02122-18
Autor:
Ramesh B. Bambal, Tridib Chaira, Kedar Purnapatre, Dilip J. Upadhyay, Madhvi Rao, Manisha Pandya, Alka Khanna, Nobuhisa Masuda
The emergence of multidrug-resistant (MDR) Gram-negative bacilli is a major concern in the treatment of nosocomial infections. Antibacterial agents with novel modes of action can be useful, as these pathogens have become resistant to almost all exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0b80f5d134267d9c62eb9fa0316fe1
https://europepmc.org/articles/PMC5913941/
https://europepmc.org/articles/PMC5913941/
Autor:
Stephen E. Clarke, Ramesh B. Bambal
Publikováno v:
Evaluation of Drug Candidates for Preclinical Development: Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1deaf40b15d7dd47bacc002480dd210
https://doi.org/10.1002/9780470574898.ch4
https://doi.org/10.1002/9780470574898.ch4
Autor:
Lalita Guntuku, V.G.M. Naidu, Ramesh B. Bambal, Kahkashan Resham, Dinesh Thummuri, Prinesh N. Patel, Vanya Shah
Publikováno v:
Chemico-biological interactions. 240
There has been a search for new anticancer agents to treat cancer resistance throughout the globe. Salinomycin (SAL), a broad spectrum antibiotic and a coccidiostat has been found to counter tumour resistance and kill cancer stem cells with better ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae9cb5f1fa9a067ba40e9ff214e620a
https://pubmed.ncbi.nlm.nih.gov/26282489
https://pubmed.ncbi.nlm.nih.gov/26282489
Publikováno v:
The Analyst. 138(20)
The aim of the present study is to develop and demonstrate the correlation between in vitro and in vivo Plasma Protein Binding (PPB) using the ultracentrifugation method for its validation by using marketed compounds like atenolol, theophylline and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b74f7cf0c5d075bb0211ba23819f805
https://pubmed.ncbi.nlm.nih.gov/23964358
https://pubmed.ncbi.nlm.nih.gov/23964358
Autor:
Ramesh B. Bambal, Robert P. Hanzlik
Publikováno v:
Archives of Biochemistry and Biophysics. 334:59-66
The action of cytochrome P450 4A1 (CYP4A1) on fatty acid substrates is characterized by a pronounced regioselectivity for omega-hydroxylation. To elucidate the chemical basis of this specificity we probed the active site of a CYP4A1 fusion protein (f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c6067303b958fba08dcac0eee24461
https://doi.org/10.1006/abbi.1996.0429
https://doi.org/10.1006/abbi.1996.0429
Autor:
Ramesh B. Bambal, Robert P. Hanzlik
Publikováno v:
Biochemical and Biophysical Research Communications. 219:445-449
The active site of an engineered, expressed fusion protein containing the sequences of cytochrome P450 4A1 (lauric acid omega-hydroxylase) and NADPH-cytochrome P450 reductase, has been probed with olefinic, acetylenic, aromatic, and other analogs of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24bbc4a2d05fd264add59e6d1bc9dfb
https://doi.org/10.1006/bbrc.1996.0253
https://doi.org/10.1006/bbrc.1996.0253