Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ramesh Arunkumar"'
Autor:
Alexandre B. Leitão, Ramesh Arunkumar, Jonathan P. Day, Nancy Hanna, Aarathi Devi, Matthew P. Hayes, Francis M. Jiggins
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Innate immune responses can be activated by pathogen-associated molecular patterns (PAMPs), danger signals released by damaged tissues, or the absence of self-molecules that inhibit immunity. As PAMPs are typically conserved acros
Externí odkaz:
https://doaj.org/article/de39d1abcbb54e31971b339b22f03e6a
Autor:
Shuyu Olivia Zhou, Ramesh Arunkumar, Amina Irfan, Shuai Dominique Ding, Alexandre B Leitão, Francis M Jiggins
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011729 (2024)
Both constitutive and inducible immune mechanisms are employed by hosts for defense against infection. Constitutive immunity allows for a faster response, but it comes with an associated cost that is always present. This trade-off between speed and f
Externí odkaz:
https://doaj.org/article/a8971a707b9c48c3b49d8c2b779cbcff
Autor:
Shuai Dominique Ding, Alexandre B Leitão, Jonathan P Day, Ramesh Arunkumar, Morgan Phillips, Shuyu Olivia Zhou, Francis M Jiggins
Publikováno v:
PLoS Genetics, Vol 18, Iss 11, p e1010453 (2022)
When an animal is infected, the expression of a large suite of genes is changed, resulting in an immune response that can defend the host. Despite much evidence that the sequence of proteins in the immune system can evolve rapidly, the evolution of g
Externí odkaz:
https://doaj.org/article/a260983ef01f47b39cdd6af40ac8004c
Autor:
Alexandre B Leitão, Ramesh Arunkumar, Jonathan P Day, Emma M Geldman, Ismaël Morin-Poulard, Michèle Crozatier, Francis M Jiggins
Publikováno v:
eLife, Vol 9 (2020)
Organisms rely on inducible and constitutive immune defences to combat infection. Constitutive immunity enables a rapid response to infection but may carry a cost for uninfected individuals, leading to the prediction that it will be favoured when inf
Externí odkaz:
https://doaj.org/article/b00a684d2c534fdbbc21d8b55e2bbd35
Autor:
Ramesh, Arunkumar, Zhou, Shuyu Olivia, Day, Jonathan, Bakare, Sherifat, Pitton, Simone, Zhang, Yexin, Hsing, Chi-Yun, O'Boyle, Sinead, Pascual-Gil, Juan, Clark, Belinda, Chandler, Rachael J, Leitao, Alexandre B, Jiggins, Francis M
Polymorphisms in immunity genes can have large effects on susceptibility to infection. To understand the origins of this variation, we have investigated the genetic basis of resistance to the parasitoid wasp Leptopilina boulardi in Drosophila melanog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8d0c9ca1904efd457624c479af892b
Autor:
Alexandre B. Leitão, Ramesh Arunkumar, Jonathan P. Day, Nancy Hanna, Aarathi Devi, Matthew P. Hayes, Francis Jiggins
Innate immune responses can be activated by pathogen-associated molecular patterns (PAMPs) or danger signals released by damaged tissues. As PAMPs are typically conserved across broad groups of pathogens but absent from the host, it is unclear whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bbdb2f4b5e6568dae53fc635265443f
https://doi.org/10.1101/2022.06.28.497890
https://doi.org/10.1101/2022.06.28.497890
Publikováno v:
G3 Genes|Genomes|Genetics. 12
Whole-genome duplication is widespread in plant evolutionary history and is followed by nonrandom gene loss to return to a diploid state. Across multiple angiosperm species, the retained genes tend to be dosage-sensitive regulatory genes such as tran
Autor:
Ramesh Arunkumar, Shuyu Olivia Zhou, Jonathan P. Day, Sherifat Bakare, Simone Pitton, Chi-Yun Hsing, Sinead O’Boyle, Juan Pascual-Gil, Belinda Clark, Rachael J. Chandler, Alexandre B. Leitão, Francis M. Jiggins
Polymorphisms in immunity genes can have large effects on susceptibility to infection. To understand the origins of this variation, we investigated the genetic basis of resistance to the parasitoid wasp Leptopilina boulardi in Drosophila melanogaster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bc71255285533092bfc32025da6f643
https://doi.org/10.1101/2022.05.27.493757
https://doi.org/10.1101/2022.05.27.493757
Organisms rely on inducible and constitutive immune defences to combat infection. Constitutive immunity enables a rapid response to infection but may carry a cost for uninfected individuals, leading to the prediction that it will be favoured when inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d0f63ec09898b09380672f77b0e1d5