Feasibility of comparing medical management and surgery (with neurosurgery or stereotactic radiosurgery) with medical management alone in people with symptomatic brain cavernoma – protocol for the Cavernomas: A Randomised Effectiveness (CARE) pilot trial

Autor: Khalid Hamandi, Julie Woodfield, Smriti Agarwal, Richard Edwards, John Williamson, Ravindran Visagan, Rustam Al-Shahi Salman, Howard Brydon, Diederik Bulters, Dawn Hennigan, Paul Leach, Conor Mallucci, Nitin Mukerji, Marios Papadopoulos, Nicholas Ross, Martin Tisdall, Carole Turner, Shungu Ushewokunze, Raghu Vindlacheruvu, Paul Brennan, Phil White, Sophie Hunter, Karen Coy, Julia Wade, James Stewart, Tom Hughes, Laura Forsyth, Kirsty Harkness, David White, Rupal Shah, Sanjay Bhate, Neil Kitchen, Peter J Hutchinson, Emanuel Cirstea, Ramesh Nair, Rebecca Hall, Varduhi Cahill, Tom Hayton, Silvia Tarantino, Christin Eltze, Jack Lee, Arlo Whitehouse, Daniel Walsh, Jacqueline Stephen, Nicola Phillips, Steff Lewis, Susan Davies, Mathew Guilfoyle, Peter S Hall, Andrew Stoddart, Francesca Colombo, Emma Richards, Greg James, Sarah Illingworth, William B Lo, Andrew Bacon, Vijeya Ganesan, Sabina Patel, Aileen R Neilson, Felicia Jennings, Saba Raza-Knight, Andrew Brodbelt, Aswin Chari, Hasan Asif, Ian Kamaly-Asl, Milan Makwana, Zubair Tahir, Allan MacRaild, Grace Vassallo, Ian Anderson, Daniel Holsgrove, Carole Chambers, Sandra Williams, Francesca Spickett-Jones, Marios C Papadopoulos, John Preston, Edward White, Adel Helmy, Sarah Ali, John Reid, Daniel Brown, Louis Taylor, Christopher Uff, Patrick Grover, Azra Banaras, Linetty Makawa, Anil Israni, Richard J Edwards, William Muirhead, Daniel Brooks, Debbie Brown, Ciaran Scott Hill, Kerry Smith, Beth Atkinson, Michelle Fawcett, Sifelani Tshuma, Oliver Kennion, Jo Howe, James J M Loan, Philip Clatworthy, Claire Hudson, Rebecca Hodnett, Madalina Roman, Mary Sikaonga, Elaine Kinsella, Mario Teo, Venetia Giannakaki, James Loan, Lauren Harris, Jack Wildman, Emmanuel Chavredakis, Nihal Gurusinghe, Alex Rossdeutsch, Anthony Wiggins, Giannis Sokratous, Lucie Ferguson, Shakeelah Patel, Sonia Raj, Oishik Raha, Janneke van Beijnum, Pragnesh Bhatt, Anna Bjornson, Nicole Broomes, Alistair Bullen, Julian Cahill, Mihai Danciut, Ronneil Digpal, Ioannis Fouyas, Lauren S Harris, Sohail Majeed, Matthias Radatz, Oliver Wroe Wright, Jessica Teasdale, Michelle Coakley, Drahoslav Sokol, Chandru Kaliaperumal, Mairi MacDonald, Sarah Risbridger, Siobhan Kearney, Ellaine Bosetta, Thomas Doke, Sonny Coskuner, Christine Kamara, Jonathan Gardner, Imron Hamina, Kishor Chaudhari, Liliana Chapas, Karen Caldwell, Sarah Holland, Tamara Tajsic, Rachael Dore, Taya Anderson, Shelley Mayor, Laura O'Malley, Samantha Glover, Janice Irvine, Annika Walch, Farah Muir, Eng Tah Goh, Andrew McDarby, Michelle Bates, Rebecca Hancox, Claudia Kate Auyeung, Elizabeth Goff, Deanna Stephens, Borislava Borislavova, Ruth Worner, Sandeep Buddha, Lisa Tucker, Sandra Dymond, Andrew Mallick, Dymona McAleer, Belinda Gunning, Emma Clarkson, Cathy Stoneley, Jibril Osman Farah, Niamh Bohnacker, Rosette Marimon, Lydia Parker, Puneet Sharma, Dan Holsgrove, Danielle McLaughlan, Tracey Marsden, Kathryn Cawley, Hellen Raffalli, Imedla Mayor, Dipek Ram, Rebecca Keeping, Katie Hennessy, Ammar Kadhim, Md Moidul Islam, Manjunath Prasad, Cheryl Webster, Vicky Slater, Saffnan Mohamed, Saba Raza Knight, Terri-Louise Cromie, Allan Brown, Ruth Pennington, Charlene Campbell, Anthony Ghosh, Teresa Fitzpatrick, Mohammed Patel, Winnington Ruiz, Mirriam Taylor, Divina Anyog, Katarzyna Tluchowska, Jackson Nolasco, Kleopatra Angelopoulou, Bethany Welch, Ida Ponce, Lucy Bailey, Mia Marsden, Angelene Cope, Deepthy Blesson, Rachel Sutton, Mary Kambafwile, Jade McAndrew

Publikováno v: BMJ Open, Vol 13, Iss 8 (2023)

Introduction The top research priority for cavernoma, identified by a James Lind Alliance Priority setting partnership was ‘Does treatment (with neurosurgery or stereotactic radiosurgery) or no treatment improve outcome for people diagnosed with a

Externí odkaz: https://doaj.org/article/df389aa5a29f4557ac19c817e505e753

Machine learning driven prediction of cerebrospinal fluid rhinorrhoea following endonasal skull base surgery: A multicentre prospective observational study

Autor: CRANIAL Consortium, Adrito Das, Danyal Z. Khan, Danail Stoyanov, Hani J. Marcus, Soham Bandyopadhyay, Benjamin E. Schroeder, Vikesh Patel, Alice O’Donnell, Neurology and Neurosurgery Interest Group, British Neurosurgical Trainee Research Collaborative, Anastasios Giamouriadis, Pragnesh Bhatt, Bhaskar Ram, Adithya Varma, Philip Weir, Brendan Hanna, Theodore C. Hirst, Patrick McAleavey, Alessandro Paluzzi, Georgios Tsermoulas, Shahzada Ahmed, Wai Cheong Soon, Yasir Arafat Chowdhury, Suhaib Abualsaud, Shumail Mahmood, Paresh Naik, Zohra Haiderkhan, Rafid Al-Mahfoudh, Andrea Perera, Mircea Rus, Adam Williams, Charles Hand, Kumar Abhinav, Cristina Cernei, Aiman Dilnawaz, Richard Mannion, Thomas Santarius, James Tysome, Rishi Sharma, Angelos G. Kolias, Neil Donnelly, Ashwin Venkatesh, Caroline Hayhurst, Amr Mohamed, Benjamin Stew, Joseph Merola, Setthasorn Zhi Yang, Mahmoud Kamel, Mohammad Habibullah Khan, Sahibzada Abrar, Christopher Mckeon, Daniel McSweeney, Mohsen Javadpour, Peter Lacy, Daniel Murray, Elena Roman, Kismet Hossain-Ibrahim, David Bennett, Nathan McSorley, Adam Hounat, Patrick Statham, Mark Hughes, Alhafidz Hamdan, Caroline Scott, Jigi Moudgil-Joshi, Anuj Bahl, Anna Bjornson, Daniel Gatt, Nick Phillips, Neeraj Kalra, Melissa Bautista, Seerat Shirazi, Catherine E. Gilkes, Christopher P. Millward, Ahmad MS. Ali, Dimitris Paraskevopoulos, Jarnail Bal, Samir Matloob, Rhannon Lobo, Nigel Mendoza, Ramesh Nair, Arthur Dalton, Adarsh Nadig, Lucas Hernandez, Nick Thomas, Eleni Maratos, Jonathan Shapey, Sinan Al-Barazi, Asfand Baig Mirza, Mohamed Okasha, Prabhjot Singh Malhotra, Razna Ahmed, Neil L. Dorward, Joan Grieve, Parag Sayal, David Choi, Ivan Cabrilo, Hugo Layard Horsfall, Jonathan Pollock, Alireza Shoakazemi, Oscar Maccormac, Guru N K. Amirthalingam, Andrew Martin, Simon Stapleton, Florence Hogg, Daniel Richardson, Kanna Gnanalingham, Omar Pathmanaban, Daniel M. Fountain, Raj Bhalla, Cathal J. Hannan, Annabel Chadwick, Alistair Jenkins, Claire Nicholson, Syed Shumon, Mohamed Youssef, Callum Allison, Graham Dow, Iain Robertson, Laurence Johann Glancz, Murugan Sitaraman, Ashwin Kumaria, Ananyo Bagchi, Simon Cudlip, Jane Halliday, Rory J. Piper, Alexandros Boukas, Meriem Amarouche, Damjan Veljanoski, Samiul Muquit, Ellie Edlmann, Haritha Maripi, Yi Wang, Mehnaz Hossain, Andrew Alalade, Syed Maroof, Pradnya Patkar, Saurabh Sinha, Showkat Mirz, Duncan Henderson, Mohammad Saud Khan, Nijaguna Mathad, Jonathan Hempenstall, Difei Wang, Pavan Marwaha, Simon Shaw, Georgios Solomou, Alina Shrestha

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

BackgroundCerebrospinal fluid rhinorrhoea (CSFR) is a common complication following endonasal skull base surgery, a technique that is fundamental to the treatment of pituitary adenomas and many other skull base tumours. The CRANIAL study explored CSF

Externí odkaz: https://doaj.org/article/57c49257e0e04c159faceaf78654f6a9

Surgical Morbidity in Relation to the Surgical Approach for Olfactory Groove Meningiomas—A Pooled Analysis of 1016 Patients and Proposal of a New Reporting System

Autor: Ekkehard M. Kasper, Farhan A. Mirza, Serdar Kaya, Robert Walker, Daniele Starnoni, Roy T. Daniel, Ramesh Nair, Fred C. Lam

Publikováno v: Brain Sciences, Vol 13, Iss 6, p 896 (2023)

Background: There is currently no consensus in the field regarding whether a frontal or lateral approach is superior for microsurgical resection of olfactory groove meningiomas (OGM). Due to the lack of uniformity in classifying lesions and inherent

Externí odkaz: https://doaj.org/article/6fdf2898c3d841cf852aaad5f369f7b3

Biochar Synthesis from Mineral- and Ash-Rich Waste Biomass, Part 1: Investigation of Thermal Decomposition Mechanism during Slow Pyrolysis

Autor: Rahul Ramesh Nair, Moni Mohan Mondal, Shanmugham Venkatachalam Srinivasan, Dirk Weichgrebe

Publikováno v: Materials, Vol 15, Iss 12, p 4130 (2022)

Synthesizing biochar from mineral- and ash-rich waste biomass (MWB), a by-product of human activities in urban areas, can result in renewable and versatile multi-functional materials, which can also cater to the need of solid waste management. Hybrid

Externí odkaz: https://doaj.org/article/da899d2cadd5401b8954a59964a97257

Clinical and biochemical characteristics of patients presenting with pituitary apoplexy

Autor: Ali Abbara, Sophie Clarke, Pei Chia Eng, James Milburn, Devavrata Joshi, Alexander N Comninos, Rozana Ramli, Amrish Mehta, Brynmor Jones, Florian Wernig, Ramesh Nair, Nigel Mendoza, Amir H Sam, Emma Hatfield, Karim Meeran, Waljit S Dhillo, Niamh M Martin

Publikováno v: Endocrine Connections, Vol 7, Iss 10, Pp 1058-1066 (2018)

Purpose: To review the clinical and biochemical characteristics and clinical outcome of patients presenting with pituitary apoplexy to a tertiary centre. Methods: We retrospectively reviewed the clinical features, predisposing factors, biochemistry

Externí odkaz: https://doaj.org/article/7fd961bc56a147ff9a5a0386e15df541