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Autor:
Rameesa D. Syed Mohammed, Francis D. O. Ablan, Nicholas M. McCann, Mohammed M. Hindi, Muriel C. Maurer
Publikováno v:
Thrombosis and haemostasis.
Factor XIII (FXIII) catalyzes formation of γ-glutamyl-ε-lysyl crosslinks between reactive glutamines (Q) and lysines (K). In plasma, FXIII is activated proteolytically (FXIII-A*) by the concerted action of thrombin and Ca2+. Cellular FXIII is activ