Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rame H, Khasawneh"'
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Breast cancer risk, development, and treatment are influenced by genetic variation in certain genes, namely those involved in cell proliferation, tumor suppression, and drug metabolism. In turn, the relevance of the aforementioned
Externí odkaz:
https://doaj.org/article/8caa0d3cca084b9099546acfd3ddcecd
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Single nucleotide polymorphisms (SNPs) in several CYP genes have been associated with altered breast cancer (BC) risk in different populations. Despite this, there is a dearth of information on the roles of these SNPs in Jordanian
Externí odkaz:
https://doaj.org/article/5916dacd0eca49a4b90ee95dad9e0ea7
Publikováno v:
Saudi Pharmaceutical Journal, Vol 27, Iss 4, Pp 484-490 (2019)
The main objective of this study is to assess the effects of CYP2C9 and VKORC1 polymorphisms on warfarin sensitivity and responsiveness in a Jordanian population during the stabilization phase of treatment. This study was conducted at the Queen Alia
Externí odkaz:
https://doaj.org/article/453fa23422714bda9530937a5e84947d
Autor:
Rame H. Khasawneh, Shirin S. Almharat, Ruba A. Al-Smadi, Lamees Abasi, Maha Al-Amr, Ali S. Alhuniti, Abdullah M. Almuhasen, Mohammad A. Dojan, Osama I. Alshdifat, ALanood Faheem
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 104:115771
The pandemic caused by SARS-CoV-2 has prompted a collaborative global effort to contain viral spread and improve health outcomes for those infected. The tracking of SARS-CoV-2 variants since the first sequence was published in January 2020 is an impo
Publikováno v:
Journal of Personalized Medicine
The purpose of this study was to investigate the effects of the SH2B3, MTHFD1L, GGCX, and ITGB3 gene variants on the efficacy of warfarin treatment and its effects on the risk of cardiovascular disorders in Jordanian patients. The selected genes and
Autor:
Laith N, Al-Eitan, Barakat Z, Elsaqa, Ayah Y, Almasri, Hatem A, Aman, Rame H, Khasawneh, Mansour A, Alghamdi
Publikováno v:
Pharmacogenomics and Personalized Medicine
Background Cardiovascular disease is one of the most common causes of morbidity and mortality worldwide. Several cardiovascular diseases require therapy with warfarin, an anticoagulant with large interindividual variability resulting in dosing diffic
Publikováno v:
Pharmacogenomics and Personalized Medicine
Backgrounds Breast cancer (BC) is one of the most widespread cancers globally. Understanding the etiology of BC may help in determining the various risk factors involved in its malignancy. Certain genetic mutations are considered to play a key role i
Publikováno v:
OncoTargets and therapy
Purpose Genetic predisposition to disease has become one of the most investigated risk factors in recent years, and breast cancer (BC) is no exception. In this study, we investigated specific genetic variants of three candidate genes belonging to the
Publikováno v:
Genes
Warfarin is an oral anticoagulant frequently used in the treatment of different cardiovascular diseases. Genetic polymorphisms in the CYP2C9 and VKORC1 genes have produced variants with altered catalytic properties. A total of 212 cardiovascular pati