Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ramchandra R. Sangana"'
Autor:
Vidya Ganapati Kattige, Srinivasa Honnegowda, Sanjay Deshmukh, Laxmikant Atmaram Gharat, Abhay Kulkarni, Neelam Sarode, Pooja Sawant, Shital Tondlekar, Neelima Khairatkar-Joshi, Vikas Karande, Dnyandeo Pisal, Satyawan Jadhav, Macchindra Tambe, Nagarajan Muthukaman, Mahamadhanif S. Shaikh, Ramchandra R. Sangana, Monali Pisat, Girish S. Gudi, Dayanidhi Behera
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:5131-5138
This letter describes the synthesis and biological evaluation of furan and dihydrofuran-fused tricyclic benzo[d]imidazole derivatives as novel mPGES-1 inhibitors, capable of inhibiting an increased PGE2 production in the disease state. Structure-acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c711ec94b372ec3592b14b193fefd59c
https://doi.org/10.1016/j.bmcl.2017.10.062
https://doi.org/10.1016/j.bmcl.2017.10.062
Autor:
Nagarajan Muthukaman, Pooja Sawant, Dnyandeo Pisal, Srinivasa Honnegowda, Abhay Kulkarni, Vidya Ganapati Kattige, Sanjay Deshmukh, Shital Tondlekar, Neelam Sarode, Satyawan Jadhav, Neelima Khairatkar-Joshi, Dayanidhi Behera, Girish S. Gudi, Ramchandra R. Sangana, Vikas Karande, Macchindra Tambe, Monali Pisat, Mahamadhanif S. Shaikh, Laxmikant Atmaram Gharat
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(7)
In an effort to identify CYP and hERG clean mPGES-1 inhibitors from the dihydrofuran-fused tricyclic benzo[d]imidazole series lead 7, an extensive structure-activity relationship (SAR) studies were performed. Optimization of A, D and E-rings in 7 aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa34d823475ba2b669394baf70bf1665
https://pubmed.ncbi.nlm.nih.gov/29519738
https://pubmed.ncbi.nlm.nih.gov/29519738
Autor:
Dinesh Pradeep Wale, Anupindi Raghuram, Shobha S. Rao, Indranil Mukhopadhyay, Neelima Khairatkar-Joshi, Sachin Sundarlal Chaudhari, Pallavi V. Karnik, Thamil Selvan Vaiyapuri, Ashok Bhausaheb Kadam, A. P. Thomas, Ramchandra R. Sangana, Girish S. Gudi, Vikram Mansingh Bhosale
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:6542-6553
A novel series of N -aryl-3,4-dihydro-1′ H -spiro[chromene-2,4′-piperidine]-1′-carboxamides was identified as transient receptor potential melastatin 8 (TRPM8) channel blockers through analogue-based rational design, synthesis and screening. De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd11b1ba720961cef81452b38a0f1e30
https://doi.org/10.1016/j.bmc.2013.08.031
https://doi.org/10.1016/j.bmc.2013.08.031
Autor:
Sahu R; Drug Development and Analysis Laboratory, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan Deemed to be University, Ghatikia, Kalinga Nagar, Bhubaneswar 751029, India., Ahmed T; Piramal Enterprises Ltd., Off Western Express High Way, Goregaon (E), Mumbai 400063, India., Sangana R; Piramal Enterprises Ltd., Off Western Express High Way, Goregaon (E), Mumbai 400063, India., Punde R; Piramal Enterprises Ltd., Off Western Express High Way, Goregaon (E), Mumbai 400063, India., Subudhi BB; Drug Development and Analysis Laboratory, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan Deemed to be University, Ghatikia, Kalinga Nagar, Bhubaneswar 751029, India. Electronic address: bbsubudhi@soa.ac.in.
Publikováno v:
Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2018 Mar 20; Vol. 151, pp. 310-316. Date of Electronic Publication: 2018 Jan 10.