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Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.

Autor: Walters LC; Nuffield Department of Medicine Research Building, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Rozbesky D; Department of Cell Biology, Faculty of Science, Charles University, Prague, Czech Republic., Harlos K; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Quastel M; Nuffield Department of Medicine Research Building, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Sun H; Nuffield Department of Medicine Research Building, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK; Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, Shenyang, China., Springer S; Department of Life Sciences and Chemistry, Jacobs University Bremen, Bremen, Germany., Rambo RP; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, UK., Mohammed F; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK., Jones EY; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., McMichael AJ; Nuffield Department of Medicine Research Building, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK. Electronic address: andrew.mcmichael@ndm.ox.ac.uk., Gillespie GM; Nuffield Department of Medicine Research Building, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK. Electronic address: geraldine.gillespie@ndm.ox.ac.uk.

Publikováno v: Cell reports [Cell Rep] 2022 Jun 14; Vol. 39 (11), pp. 110959.

Solution structure of deglycosylated human IgG1 shows the role of C H 2 glycans in its conformation.

Autor: Spiteri VA; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London, United Kingdom., Doutch J; ISIS Facility, STFC Rutherford Appleton Laboratory, Harwell Campus, Didcot, Oxfordshire, United Kingdom., Rambo RP; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom., Gor J; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London, United Kingdom., Dalby PA; Department of Biochemical Engineering, University College London, London, United Kingdom., Perkins SJ; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London, United Kingdom. Electronic address: s.perkins@ucl.ac.uk.

Publikováno v: Biophysical journal [Biophys J] 2021 May 04; Vol. 120 (9), pp. 1814-1834. Date of Electronic Publication: 2021 Mar 04.

Controlling Protein Nanocage Assembly with Hydrostatic Pressure.

Autor: Le Vay K; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, U.K.; Bristol Centre for Functional Nanomaterials, HH Wills Physics Laboratory, University of Bristol, Tyndall Avenue, Bristol BS8 1TL, U.K., Carter BM; School of Cellular and Molecular Medicine, University of Bristol, University Walk, Bristol BS8 1TD, U.K., Watkins DW; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, U.K., Dora Tang TY; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, U.K., Ting VP; Bristol Composites Institute (ACCIS), Department of Mechanical Engineering, University of Bristol, Queen's Building, Bristol BS8 1TR, U.K., Cölfen H; Department of Chemistry, University of Konstanz, Universitätsstraße 10, 78457 Konstanz, Germany., Rambo RP; Diamond House, Diamond Light Source Ltd., Harwell Science and Innovation Campus, Fermi Ave., Didcot OX11 0DE, U.K., Smith AJ; Diamond House, Diamond Light Source Ltd., Harwell Science and Innovation Campus, Fermi Ave., Didcot OX11 0DE, U.K., Ross Anderson JL; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, U.K.; BrisSynBio Synthetic Biology Research Centre, Life Sciences Building, University of Bristol, Tyndall Avenue, Bristol BS8 1TQ, U.K., Perriman AW; School of Cellular and Molecular Medicine, University of Bristol, University Walk, Bristol BS8 1TD, U.K.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2020 Dec 09; Vol. 142 (49), pp. 20640-20650. Date of Electronic Publication: 2020 Nov 30.