Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ramaswamy Krishnamoorthi"'
Autor:
Dennis Karote, Brandon Walker, Huaien Dai, Ramaswamy Krishnamoorthi, Janis Voo, Shyamala Rajagopalan
Publikováno v:
Journal of Chemistry, Vol 2013 (2013)
The reactions of chemical warfare agent simulants, 2-chloroethyl ethyl sulfide (2-CEES) and di-i-propyl fluoro phosphate (DFP), in fluids have been investigated. Data analyses confirm the major degradation pathway to be hydrolysis of 2-CEES to 2-hydr
Externí odkaz:
https://doaj.org/article/6142121453a3456dbf267d10d6203e63
Publikováno v:
Journal of Biological Chemistry. 289:28399-28410
Insect β-glucan recognition protein (βGRP), a pathogen recognition receptor for innate immune responses, detects β-1,3-glucan on fungal surfaces via its N-terminal carbohydrate-binding domain (N-βGRP) and triggers serine protease cascades for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30145022d653e5c38ace228286119da1
https://doi.org/10.1074/jbc.m114.583971
https://doi.org/10.1074/jbc.m114.583971
Autor:
Shyamala Rajagopalan, Dennis Karote, Ramaswamy Krishnamoorthi, Brandon Walker, Janis Voo, Huaien Dai
Publikováno v:
Journal of Chemistry, Vol 2013 (2013)
The reactions of chemical warfare agent simulants, 2-chloroethyl ethyl sulfide (2-CEES) and di-i-propyl fluoro phosphate (DFP), in fluids have been investigated. Data analyses confirm the major degradation pathway to be hydrolysis of 2-CEES to 2-hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99bb6e6abdf6af7e3434fba5cf6be6a0
https://doi.org/10.1155/2013/641620
https://doi.org/10.1155/2013/641620
Autor:
Yasuaki Hiromasa, Michael R. Kanost, David G. VanderVelde, Huaien Dai, Daisuke Takahashi, Ramaswamy Krishnamoorthi, Jeffrey A. Fabrick
Publikováno v:
Biochemistry. 52:161-170
In response to invading microorganisms, insect β-1,3-glucan recognition protein (βGRP), a soluble receptor in the hemolymph, binds to the surfaces of bacteria and fungi and activates serine protease cascades that promote destruction of pathogens by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0376d14a3b9d06b4e427cdd89fbdedaa
https://doi.org/10.1021/bi301440p
https://doi.org/10.1021/bi301440p
Publikováno v:
Journal of Biological Chemistry. 279:47833-47839
Most types of plant phospholipase D (PLD) require Ca(2+) for activity, but how Ca(2+) affects PLD activity is not well understood. We reported previously that Ca(2+) binds to the regulatory C2 domain that occurs in the N terminus of the Ca(2+)-requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197c0916591f2ffa296025462e2eac5b
https://doi.org/10.1074/jbc.m402789200
https://doi.org/10.1074/jbc.m402789200
Publikováno v:
Biochemistry. 41:10323-10331
Removal of flap DNA intermediates in DNA replication and repair by flap endonuclease-1 (FEN-1) is essential for mammalian genome integrity. Divalent metal ions, Mg(2+) or Mn(2+), are required for the active center of FEN-1 nucleases. However, it rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b913eb6bb814f1253ad32617cd18c68
https://doi.org/10.1021/bi025841s
https://doi.org/10.1021/bi025841s
Publikováno v:
Biochemistry. 41:9572-9579
The side chains of Arg 50 and Arg 52 at positions P6' and P8', respectively, anchor the binding loop to the protein scaffold by means of hydrogen bonds in Cucurbita maximatrypsin inhibitor-V (CMTI- V), a potato I family member. Here, we have investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83fe306aa48d5eb6afdc5fdb41e026c8
https://doi.org/10.1021/bi0258952
https://doi.org/10.1021/bi0258952
Publikováno v:
Biochemistry. 41:4546-4553
Hydrolysis of phospholipids by plant phospholipase Dbeta (PLDbeta) requires phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2]. Here we show that PLDbeta is stimulated by different polyphosphoinositides, among which PI(4,5)P2 is most effective. On the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b63905b1cb1f03a4819fd0a44df71e
https://doi.org/10.1021/bi0158775
https://doi.org/10.1021/bi0158775
Publikováno v:
The FASEB Journal. 28
Insect β-glucan recognition protein (βGRP), a pathogen recognition receptor for innate immune responses, detects β-1,3-glucan on fungal surfaces via its N-terminal carbohydrate binding domain (N-βGRP) and triggers serine protease cascades leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::198ee4826b2b2a447c7d0f19b3ebf635
https://doi.org/10.1096/fasebj.28.1_supplement.1007.4
https://doi.org/10.1096/fasebj.28.1_supplement.1007.4
Disulfide bond effects on protein stability: Designed variants ofCucurbita maximatrypsin inhibitor-V
Autor:
Chao-Wei Chen, Lisa Wen, Ramaswamy Krishnamoorthi, Maria I. Zavodszky, Michal Zolkiewski, Jenq-Kuen Huang
Publikováno v:
Protein Science. 10:149-160
Attempts to increase protein stability by insertion of novel disulfide bonds have not always been successful. According to the two current models, cross-links enhance stability mainly through denatured state effects. We have investigated the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01adf1cd77a5c1ad7182a2063a176e48
https://doi.org/10.1110/ps.26801
https://doi.org/10.1110/ps.26801