Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Ramaswamy Kannappan"'
Autor:
John Henderson, Praveen K. Dubey, Mallikarjun Patil, Sarojini Singh, Shubham Dubey, Rajasekaran Namakkal Soorappan, Ramaswamy Kannappan, Palaniappan Sethu, Gangjian Qin, Jianyi Zhang, Prasanna Krishnamurthy
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Doxorubicin (DOX, an anthracycline) is a widely used chemotherapy agent against various forms of cancer; however, it is also known to induce dose-dependent cardiotoxicity leading to adverse complications. Investigating the underlying molecular mechan
Externí odkaz:
https://doaj.org/article/510ece05279d4d22bb932c972f4f1856
Autor:
Ramaswamy Kannappan, Alex Matsuda, João Ferreira-Martins, Eric Zhang, Giorgia Palano, Anna Czarna, Mauricio Castro Cabral-Da-Silva, Adriana Bastos-Carvalho, Fumihiro Sanada, Noriko Ide, Marcello Rota, Maria A. Blasco, Manuel Serrano, Piero Anversa, Annarosa Leri
Publikováno v:
EBioMedicine, Vol 16, Iss C, Pp 224-237 (2017)
p53 is an important modulator of stem cell fate, but its role in cardiac progenitor cells (CPCs) is unknown. Here, we tested the effects of a single extra-copy of p53 on the function of CPCs in the presence of oxidative stress mediated by doxorubicin
Externí odkaz:
https://doaj.org/article/7447d72e79c84aae90e8708bafb7ff25
Autor:
Wesley LaBarge, Saidulu Mattapally, Ramaswamy Kannappan, Vladimir G Fast, Daniëlle Pretorius, Joel L Berry, Jianyi Zhang
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0223424 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0219442.].
Externí odkaz:
https://doaj.org/article/4314de432294431799961d9e097797f7
Autor:
Wesley LaBarge, Saidulu Mattappally, Ramaswamy Kannappan, Vladimir G Fast, Daniëlle Pretorius, Joel L Berry, Jianyi Zhang
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219442 (2019)
Functional myocardium derived from human induced pluripotent stem cells (hiPSCs) can be impactful for cardiac disease modeling, drug testing, and the repair of injured myocardium. However, when hiPSCs are differentiated into cardiomyocytes, they do n
Externí odkaz:
https://doaj.org/article/223bee8b033940dc83f383bb64809d46
Autor:
Arvind Palanisamy, Ramaswamy Kannappan, Zhiqiang Xu, Audrey Martino, Matthew B Friese, Justin D Boyd, Gregory Crosby, Deborah J Culley
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191160 (2018)
Synthetic oxytocin (sOT) is widely used during labor, yet little is known about its effects on fetal brain development despite evidence that it reaches the fetal circulation. Here, we tested the hypothesis that sOT would affect early neurodevelopment
Externí odkaz:
https://doaj.org/article/a1e7df645be54081ba9554312d497d4a
Autor:
Wesley LaBarge, Andrés Morales, Daniëlle Pretorius, Asher M. Kahn-Krell, Ramaswamy Kannappan, Jianyi Zhang
Publikováno v:
Micromachines, Vol 10, Iss 9, p 570 (2019)
Free from the limitations posed by exogenous scaffolds or extracellular matrix-based materials, scaffold-free engineered tissues have immense clinical potential. Biomaterials may produce adverse responses, interfere with cell–cell interaction, or a
Externí odkaz:
https://doaj.org/article/8866dd7af930458e9fb7d78c7cadba33
Autor:
Marianna Meo, Olivier Meste, Sergio Signore, Andrea Sorrentino, Antonio Cannata, Yu Zhou, Alex Matsuda, Marco Luciani, Ramaswamy Kannappan, Polina Goichberg, Annarosa Leri, Piero Anversa, Marcello Rota
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 2 (2016)
BackgroundDiabetes is associated with prolongation of the QT interval of the electrocardiogram and enhanced dispersion of ventricular repolarization, factors that, together with atherosclerosis and myocardial ischemia, may promote the occurrence of e
Externí odkaz:
https://doaj.org/article/645bd8cfb6bb49b49d69c158b3b48c2a
Publikováno v:
Toxins, Vol 2, Iss 10, Pp 2428-2466 (2010)
Traditional medicine and diet has served mankind through the ages for prevention and treatment of most chronic diseases. Mounting evidence suggests that chronic inflammation mediates most chronic diseases, including cancer. More than other transcript
Externí odkaz:
https://doaj.org/article/08490dac465e40dfb65f764d133543ad
Autor:
Bharat B. Aggarwal, Sushovan Guha, Sunil Krishnan, Veerabhadran Baladandayuthapani, Caimiao Wei, Parmeswaran Diagaradjane, Amit Deorukhkar, Ramaswamy Kannappan, Simone Reuter, Bokyung Sung, Vivek R. Yadav, Sahdeo Prasad
Purpose: Development of chemoresistance, poor prognosis, and metastasis often renders the current treatments for colorectal cancer (CRC) ineffective. Whether ursolic acid, a component of numerous medicinal plants, either alone or in combination with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa8b427f30e8633d926900cb2af68c6
https://doi.org/10.1158/1078-0432.c.6519765.v1
https://doi.org/10.1158/1078-0432.c.6519765.v1
Autor:
Bharat B. Aggarwal, Madan M. Chaturvedi, Simone Reuter, Vivek R. Yadav, Bokyung Sung, Sahdeo Prasad, Jayaraj Ravindran, Ramaswamy Kannappan
Supplementary Figure 1 from γ-Tocotrienol Promotes TRAIL-Induced Apoptosis through Reactive Oxygen Species/Extracellular Signal-Regulated Kinase/p53–Mediated Upregulation of Death Receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a221c6f3ed23c3bc0072fd055b2c0d7
https://doi.org/10.1158/1535-7163.22484900.v1
https://doi.org/10.1158/1535-7163.22484900.v1