Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Ramareddy V. Guntaka"'
Publikováno v:
International Journal of Cell Biology, Vol 2009 (2009)
Y-box binding protein YB-1 is a multifunctional protein involved in cell proliferation, regulation of transcription and translation. Our previous study indicated that disruption of one allele of Chk-YB-1b gene in DT-40 cells resulted in major defects
Externí odkaz:
https://doaj.org/article/86c7d46936a74158a6bd2a3205c7beee
Publikováno v:
American Journal of Hypertension. 30:1049-1052
Established cardiac fibrosis (ECF) with symptomatic heart failure preserved ejection fraction represents an ever-increasing segment of the hypertensive population. The regression of ECF with attendant improvement in myocardial stiffness and symptomat
Publikováno v:
ISRN Virology. 2014:1-11
Hepatitis C virus infection is a major health problem all over the world. A large proportion of patients infected by HCV develop liver cirrhosis or cancer. However, the mechanism(s) remain to be elucidated. Since HCV does not carry any known oncogene
Autor:
Ramareddy V Guntaka
Publikováno v:
OBM Hepatology and Gastroenterology. 3:1-1
Liver fibrosis leading to cirrhosis and cancer affects millions of people and causes thousands of deaths all over the world. Many signaling pathways could be targeted to block fibrosis but these are not successful. Reviewing recent literature and fro
Autor:
Mark Heckle, Ritin Bomb, Karl T. Weber, Salvatore Mancarella, Yao Sun, Ivan C. Gerling, Ramareddy V. Guntaka
Myofibroblasts (myoFb) are phenotypically transformed, contractile fibroblast-like cells expressing α-smooth muscle actin microfilaments. They are integral to collagen fibrillogenesis with scar tissue formation at sites of repair irrespective of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ab4ee6b175936c1edcc2d01fd8ba77
https://europepmc.org/articles/PMC4932866/
https://europepmc.org/articles/PMC4932866/
Publikováno v:
Biochemistry. 46:11240-11252
We have previously demonstrated site-specific delivery of antiparallel phosphorothioate triplex forming oligonucleotide (TFO) specific to -165 to -141 promoter region of alpha1(I) collagen (abbreviated as APS165) to hepatic stellate cells (HSCs) of f
Autor:
Kevin P. Newman, Karl T. Weber, R. Justin McCullough, Ramareddy V. Guntaka, Kodangudi B. Ramanathan, Yao Sun
Publikováno v:
Cardiac Fibrosis and Heart Failure: Cause or Effect? ISBN: 9783319174365
Cardiac fibrosis interferes with the structural homogeneity of the myocardium in hypertensive heart disease (HHD). Its morphologic presentations include: widely scattered microscopic scars which have replaced myocytes lost to necrosis; and a perivasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60695ded405fe04221f0daff0fcf5c95
https://doi.org/10.1007/978-3-319-17437-2_6
https://doi.org/10.1007/978-3-319-17437-2_6
Autor:
Rekha Thippavazzula, Chandra Madhavi, Farees Nafeesa, Aejaz M. Habib, M. N. Khaja, C M Habibullah, Ramareddy V. Guntaka
Publikováno v:
Infection, Genetics and Evolution. 6:198-204
The prevalence of hepatitis C virus (HCV) infection in the general population and in various high risk groups in south India was assessed. A total of 258 out of 3589 (7.1%) subjects (both general and risk groups) tested positive for HCV RNA by RT-PCR
Autor:
Ram I. Mahato, Kun Cheng, Daniel W. Fraga, C. Zhang, A O Gaber, Ramareddy V. Guntaka, Malak Kotb
Publikováno v:
Gene Therapy. 11:1105-1116
Islet transplantation is limited by islet graft failure due to poor revascularization, host immune rejection and nonspecific inflammatory response. Delivery of human vascular endothelial growth factor (hVEGF) gene to the islets is likely to promote i
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 35:22-31
Triplex-forming oligonucleotides (TFOs) have gained prominence in the recent years because of their potential applications in antigene therapy. In particular they have been used as (i) inducers of site-specific mutations, (ii) reagents that selective