Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ramani Soundararajan"'
Autor:
Ramani Soundararajan, Helena Hernández-Cuervo, Timothy M Stearns, Anthony J Griswold, Sahebgowda Sidramagowda Patil, Jutaro Fukumoto, Venkata Ramireddy Narala, Lakshmi Galam, Richard Lockey, Narasaiah Kolliputi
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Critically ill patients on supplemental oxygen therapy eventually develop acute lung injury (ALI). Reactive oxygen species (ROS) produced during ALI perturbs the mitochondrial dynamics resulting in cellular damage. Genetic deletion of the
Externí odkaz:
https://doaj.org/article/60d6092c74c549c8962d337265289e32
Autor:
Jutaro Fukumoto, Muling Lin, Mudassir Meraj Banday, Sahebgowda Sidramagowda Patil, Sudarshan Krishnamurthy, Mason Breitzig, Ramani Soundararajan, Lakshmi Galam, Venkata Ramireddy Narala, Colleen Johns, Kapilkumar Patel, John Dunning, Richard F. Lockey, Nirmal S. Sharma, Narasaiah Kolliputi
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Rationale: Idiopathic pulmonary fibrosis (IPF) is characterized by mitochondrial dysfunction. However, details about the non-mitochondrial enzymes that sustain the proliferative nature of IPF are unclear. Aconitases are a family of enzymes that susta
Externí odkaz:
https://doaj.org/article/8d76ad8838d241ecaf18d06e8a420def
Autor:
Sahebgowda Sidramagowda Patil, Ramani Soundararajan, Jutaro Fukumoto, Mason Breitzig, Helena Hernández-Cuervo, Matthew Alleyn, Muling Lin, Venkata Ramireddy Narala, Richard Lockey, Narasaiah Kolliputi, Lakshmi Galam
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Acute lung injury (ALI) and its severe manifestation, acute respiratory distress syndrome (ARDS), are treated with high concentrations of supplementary oxygen. However, prolonged exposure to high oxygen concentrations stimulates the production of rea
Externí odkaz:
https://doaj.org/article/ac4bacf627a34f0aa4a82b0dc7dac8a1
Autor:
Helena Hernández-Cuervo, Ramani Soundararajan, Sahebgowda Sidramagowda Patil, Mason Breitzig, Matthew Alleyn, Lakshmi Galam, Richard Lockey, Vladimir N. Uversky, Narasaiah Kolliputi
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Acute Lung Injury (ALI), characterized by bilateral pulmonary infiltrates that restrict gas exchange, leads to respiratory failure. It is caused by an innate immune response with white blood cell infiltration of the lungs, release of cytokines, an in
Externí odkaz:
https://doaj.org/article/0e3e6ed22c1f41d8a49d8219c3eafa63
Autor:
Sahebgowda Sidramagowda Patil, Helena Hernández-Cuervo, Jutaro Fukumoto, Sudarshan Krishnamurthy, Muling Lin, Matthew Alleyn, Mason Breitzig, Venkata Ramireddy Narala, Ramani Soundararajan, Richard F. Lockey, Narasaiah Kolliputi, Lakshmi Galam
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Acute lung injury (ALI), a milder form of acute respiratory distress syndrome (ARDS), is a leading cause of mortality in older adults with an increasing prevalence. Oxygen therapy, is a common treatment for ALI, involving exposure to a high concentra
Externí odkaz:
https://doaj.org/article/dff314d6405e49d7b9de6cf624b94c48
Autor:
Emma Westermann-Clark, Ramani Soundararajan, Jutaro Fukumoto, Sahebgowda Sidramagowda Patil, Timothy M. Stearns, Smita Saji, Alexander Czachor, Helena Hernandez-Cuervo, Mason Breitzig, Sudarshan Krishnamurthy, Richard F. Lockey, Narasaiah Kolliputi
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 283 (2022)
Abnormalities in airway epithelia and lung parenchyma are found in Atp8b1 mutant mice, which develop pulmonary fibrosis after hyperoxic insult. Microarray and ingenuity pathway analysis (IPA) show numerous transcripts involved in ciliogenesis are dow
Externí odkaz:
https://doaj.org/article/c543cc6e09624b9d88bffc5c6421d434
Compound Heterozygosity for Y Box Proteins Causes Sterility Due to Loss of Translational Repression.
Autor:
Elizabeth Snyder, Ramani Soundararajan, Manju Sharma, Andrea Dearth, Benjamin Smith, Robert E Braun
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005690 (2015)
The Y-box proteins YBX2 and YBX3 bind RNA and DNA and are required for metazoan development and fertility. However, possible functional redundancy between YBX2 and YBX3 has prevented elucidation of their molecular function as RNA masking proteins and
Externí odkaz:
https://doaj.org/article/245d425d35e147d6ac0c2ad93f027d8d
Autor:
Ramani Soundararajan, Jungyeon Won, Timothy M Stearns, Jeremy R Charette, Wanda L Hicks, Gayle B Collin, Jürgen K Naggert, Mark P Krebs, Patsy M Nishina
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110299 (2014)
Mutations in the membrane frizzled-related protein (MFRP/Mfrp) gene, specifically expressed in the retinal pigment epithelium (RPE) and ciliary body, cause nanophthalmia or posterior microphthalmia with retinitis pigmentosa in humans, and photorecept
Externí odkaz:
https://doaj.org/article/434f634475b741999deb8a83c8342dfb
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:AB335
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06f3a246fecf7ce59f4af4ba33a48834
https://doi.org/10.1016/j.jaci.2022.12.780
https://doi.org/10.1016/j.jaci.2022.12.780
Autor:
Ramani Soundararajan, Sai Manasa Varanasi, Sahebgowda Sidramagowda Patil, Sriraja Srinivas, Helena Hernández‐Cuervo, Alexander Czachor, Adeeb Bulkhi, Jutaro Fukumoto, Lakshmi Galam, Richard F. Lockey, Narasaiah Kolliputi
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 36(2)
Adenosine deaminase acting on RNA 2 (ADAR2), an RNA editing enzyme is involved in a site-selective modification of adenosine (A) to inosine (I) in double-stranded RNA (dsRNA). Its role in the lungs is unknown. The phenotypic characterization of Adarb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12051a0e740731925a0ee9f46d9227d
https://pubmed.ncbi.nlm.nih.gov/34985777
https://pubmed.ncbi.nlm.nih.gov/34985777