Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ramani R. Ranatunge"'
Autor:
A. Mark Trocha, David S. Garvey, Michael E. Augustyniak, Stewart K. Richardson, Mathew J. Shumway, David R. Janero, Delano V. Young, L. Gordon Letts, James L. Ellis, Ramani R. Ranatunge, Irina S. Zemtseva, Vijay Dhawan
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:2589-2599
A series of glycolamide naproxen prodrugs containing a nitrate group as a nitric oxide (NO) donor moiety has been synthesized. These compounds were evaluated for their anti-inflammatory activity, naproxen release, and gastric tolerance. Compounds 4a,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83310c66cd24419b8dc7b5347da6cce4
https://doi.org/10.1016/j.bmc.2005.11.040
https://doi.org/10.1016/j.bmc.2005.11.040
Autor:
David R. Janero, Ramani R. Ranatunge, Matthew J. Shumway, Delano V. Young, James L. Ellis, Joseph D. Schroeder, S. William Tam, David S. Garvey, A. Mark Trocha, L. Gordon Letts, Madhavi G. Murty, Michael E. Augustyniak, Richard A. Earl, Upul K. Bandarage, Allison M. Martino, Stewart K. Richardson
Publikováno v:
Journal of Medicinal Chemistry. 47:2180-2193
The synthesis of a series of novel pyrazoles containing a nitrate (ONO(2)) moiety as a nitric oxide (NO)-donor functionality is reported. Their COX-1 and COX-2 inhibitory activities in human whole blood are profiled. Our data demonstrate that pyrazol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c82949f333971ca18cb6135ae949209
https://doi.org/10.1021/jm030276s
https://doi.org/10.1021/jm030276s
Autor:
L. Gordon Letts, Delano V. Young, Madhavi G. Murty, Stewart K. Richardson, Ramani R. Ranatunge, Allison M. Martino, David R. Janero, David S. Garvey, Irina S. Zemetseva
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:1357-1366
Novel series of pyrazolo[5,1- b ]1,3-oxazolidines, pyrazolo[5,1- b ]1,3-oxazines and imidazolidino[1,2- d ]pyrazoles were synthesized. These compounds were evaluated in vitro for their ability to inhibit cyclooxygenase-1 (COX-1) and cyclooxygenase-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6118b32f5cf2b3e31ef16a3317c727
https://doi.org/10.1016/j.bmc.2004.01.012
https://doi.org/10.1016/j.bmc.2004.01.012
Publikováno v:
Organometallics. 13:500-510
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bda40c021752dc47354841e5fc6e477c
https://doi.org/10.1021/om00014a023
https://doi.org/10.1021/om00014a023
Autor:
Noel W. Duffy, Brian H. Robinson, P. Ramani R. Ranatunge-Bandarage, Jim Simpson, S. Margaret Johnston
Publikováno v:
Organometallics. 13:511-521
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5382d093137757b9d26f25535c1cd0a6
https://doi.org/10.1021/om00014a024
https://doi.org/10.1021/om00014a024
Autor:
Ramani R. Ranatunge, et al. et al.
Publikováno v:
ChemInform. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c725c7837339c4ac91842fe10326556d
https://doi.org/10.1002/chin.200516109
https://doi.org/10.1002/chin.200516109