Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ramandeep K Babbra"'
Autor:
Pradeep S Chauhan, Kevin Chen, Ramandeep K Babbra, Wenjia Feng, Nadja Pejovic, Armaan Nallicheri, Peter K Harris, Katherine Dienstbach, Andrew Atkocius, Lenon Maguire, Faridi Qaium, Jeffrey J Szymanski, Brian C Baumann, Li Ding, Dengfeng Cao, Melissa A Reimers, Eric H Kim, Zachary L Smith, Vivek K Arora, Aadel A Chaudhuri
Publikováno v:
PLoS Medicine, Vol 18, Iss 8, p e1003732 (2021)
BackgroundThe standard of care treatment for muscle-invasive bladder cancer (MIBC) is radical cystectomy, which is typically preceded by neoadjuvant chemotherapy. However, the inability to assess minimal residual disease (MRD) noninvasively limits ou
Externí odkaz:
https://doaj.org/article/68ac59a93c0e4cf082db6dfecd686ee0
Autor:
Pradeep S. Chauhan, Alexander Shiang, Irfan Alahi, R. Taylor Sundby, Wenjia Feng, Bilge Gungoren, Cayce Nawaf, Kevin Chen, Ramandeep K. Babbra, Peter K. Harris, Faridi Qaium, Casey Hatscher, Anna Antiporda, Lindsey Brunt, Lindsey R. Mayer, Jack F. Shern, Brian C. Baumann, Eric H. Kim, Melissa A. Reimers, Zachary L. Smith, Aadel A. Chaudhuri
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-6 (2023)
Abstract Circulating tumor DNA (ctDNA) sensitivity remains subpar for molecular residual disease (MRD) detection in bladder cancer patients. To remedy this problem, we focused on the biofluid most proximal to the disease, urine, and analyzed urine tu
Externí odkaz:
https://doaj.org/article/6c08dcfd52c5447997c27e3e554c3cca
Autor:
Kevin Chen, Pradeep S. Chauhan, Ramandeep K. Babbra, Wenjia Feng, Eric H. Kim, Zachary L. Smith, Vivek K. Arora, Aadel A. Chaudhuri
Publikováno v:
Journal of Clinical and Translational Science, Vol 5, Pp 113-114 (2021)
ABSTRACT IMPACT: Urine tumor DNA non-invasively detects minimal residual disease and infers tumor mutational burden in locally advanced bladder cancer prior to radical cystectomy, which may potentially enable the selection of patients for bladder-spa
Externí odkaz:
https://doaj.org/article/f94b2114ff41450a887fc12541e7fb63
Autor:
Pradeep Singh Chauhan, Alexander L. Shiang, Irfan Alahi, R. Taylor Sundby, Wenjia Feng, Bilge Gungoren, Cayce Nawaf, Kevin Chen, Ramandeep K. Babbra, Peter K. Harris, Faridi Qaium, Casey Hatscher, Anna Antiporda, Lindsey Brunt, Lindsey R. Mayer, Jack F. Shern, Brian C. Baumann, Eric H. Kim, Melissa A. Reimers, Zachary L. Smith, Aadel A. Chaudhuri
Publikováno v:
Cancer Research. 83:2219-2219
Background: Circulating cell-free tumor DNA (ctDNA) analysis for minimal residual disease (MRD) detection is transforming cancer care. However, the sensitivity of these approaches remains subpar and there is significant risk of false negative results
Autor:
Irfan Alahi, Pradeep S. Chauhan, Alexander L. Shiang, Jace Webster, Ha X. Dang, Lilli Greiner, Breanna yang, Elisa M. Ledet, Ramandeep K. Babbra, Wenjia Feng, Peter K. Harris, Ellen B. Jaeger, Patrick J. Miller, Sydney A. Caputo, Giordano Cittolin Santos, Oliver Sartor, Russell K. Pachynski, Christopher A. Maher, Aadel A. Chaudhuri
Publikováno v:
Cancer Research. 83:6698-6698
Background: Androgen receptor signaling inhibitors (ARSI) such abiraterone and enzalutamide have significantly improved clinical outcomes in metastatic castrate-resistant prostate cancer (mCRPC) patients. However, patients with genomic alterations in
Autor:
Faridi Qaium, Wenjia Feng, Dengfeng Cao, Li Ding, Katherine Dienstbach, Ramandeep K. Babbra, Jeffrey J. Szymanski, Aadel A. Chaudhuri, Zachary L. Smith, Melissa A. Reimers, Brian C. Baumann, Nadja Pejovic, Vivek K. Arora, Peter K. Harris, Yi Huang, Eric H. Kim, Andrew Atkocius, Lenon Maguire, Kevin Chen, Pradeep S. Chauhan
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 111:e258-e259
Purpose/Objective(s) Standard-of-care for treating muscle-invasive bladder cancer (MIBC) typically involves radical cystectomy, which is a morbid procedure. Nonoperative treatment including chemoradiation is a standard-of-care alternative, but it req
Autor:
Alexander Shiang, Pradeep S. Chauhan, Ha X. Dang, Jace Webster, Elisa M. Ledet, Ramandeep K Babbra, Wenjia Feng, Peter K. Harris, Ellen B. Jaeger, Patrick Miller, Sydney Caputo, Giordano Fabricio Cittolin Santos, Russell Kent Pachynski, A. Oliver Sartor, Christopher Maher, Aadel A Chaudhuri
Publikováno v:
Journal of Clinical Oncology. 40:171-171
171 Background: Patients with metastatic castrate-resistant prostate cancer (mCRPC) have a variety of different systemic therapy options, yet survival outcomes remain poor. To minimize the chance of rapid resistance, it is critical to be able to pers
Autor:
Pradeep S. Chauhan, Kevin Chen, Ramandeep K. Babbra, Wenjia Feng, Nadja Pejovic, Armaan Nallicheri, Peter K. Harris, Katherine Dienstbach, Andrew Atkocius, Lenon Maguire, Faridi Qaium, Jeffrey J. Szymanski, Brian C. Baumann, Li Ding, Dengfeng Cao, Melissa A. Reimers, Eric H. Kim, Zachary L. Smith, Vivek K. Arora, Aadel A. Chaudhuri
Publikováno v:
PLOS Medicine. 18:e1003876
Autor:
Aadel A. Chaudhuri, Kevin Chen, Wenjia Feng, Pradeep S. Chauhan, Eric H. Kim, Ramandeep K. Babbra, Zachary L. Smith, Vivek K. Arora
Publikováno v:
Journal of Clinical and Translational Science. 5:113-114
IMPACT: Urine tumor DNA non-invasively detects minimal residual disease and infers tumor mutational burden in locally advanced bladder cancer prior to radical cystectomy, which may potentially enable the selection of patients for bladder-sparing trea
Autor:
Vivek K. Arora, Eric H. Kim, Pradeep S. Chauhan, Ramandeep K. Babbra, Armaan Nallicheri, Faridi Qaium, Zachary L. Smith, Aadel A. Chaudhuri, Melissa A. Reimers, Peter K. Harris, Wenjia Feng, Brian C. Baumann, Katherine Dienstbach, Lenon Maguire, Andrew Atkocius, Kevin Chen
Publikováno v:
Cancer Research. 81:547-547
Objective: Standard-of-care for muscle-invasive bladder cancer (MIBC) is neoadjuvant chemotherapy followed by radical cystectomy. The inability to assess molecular residual disease (MRD) noninvasively limits our ability to offer bladder-sparing treat