High fat diet worsens pathology and impairment in an Alzheimer’s mouse model, but not by synergistically decreasing cerebral blood flow

Autor: Mohammad Haft-Javaherian, Muse, Chris B. Schaffer, Brendah N. Njiru, Ramanauskaite Em, Pietro Michelucci, Madison Swallow, Nozomi Nishimura, Nancy E. Ruiz-Uribe, Muhammad Ali, Lindsay K. Vinarcsik, Kaja Falkenhain, Cruz Hernández Jc, Mohapatra A, Oliver Bracko

Obesity is linked to increased risk for and severity of Alzheimer’s disease (AD). Cerebral blood flow (CBF) reductions are an early feature of AD and are also linked to obesity. We showed that non-flowing capillaries, caused by adhered neutrophils,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d66b6eb71bfec5f962b2315ba9d8e3

Multi-dimensional immunoproteomics coupled with in vitro recapitulation of oncogenic NRAS ^Q61R identifies diagnostically relevant autoantibody biomarkers in thyroid neoplasia.

Autor: Belousov PV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. Electronic address: belousp@gmail.com., Afanasyeva MA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Gubernatorova EO; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia; Biological Faculty, Lomonosov Moscow State University, Moscow, Russia., Bogolyubova AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia; Center for Genetics and Life Sciences, Educational Center «Sirius», Sochi, Russia., Uvarova AN; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Putlyaeva LV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia; Center of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russia., Ramanauskaite EM; Biological Faculty, Lomonosov Moscow State University, Moscow, Russia., Kopylov AT; Institute of Biomedical Chemistry, Moscow, Russia., Demin DE; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia; Moscow Institute of Physics and Technology, Moscow, Russia., Tatosyan KA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Ustiugova AS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia; Biological Faculty, Lomonosov Moscow State University, Moscow, Russia., Prokofjeva MM; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Lanshchakov KV; National Medical Research Center for Endocrinology, Ministry of Health of the Russian Federation, Moscow, Russia; Central Clinical Hospital of the Presidential Administration of the Russian Federation, Moscow, Russia., Vanushko VE; National Medical Research Center for Endocrinology, Ministry of Health of the Russian Federation, Moscow, Russia., Zaretsky AR; Shemyakin-Ovchinnikov Research Institute for Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia; Evrogen Lab LLC, Moscow, Russia., Severskaia NV; Tsyb Medical Radiological Research Center, Ministry of Health of the Russian Federation, Obninsk, Russia., Dvinskikh NY; Tsyb Medical Radiological Research Center, Ministry of Health of the Russian Federation, Obninsk, Russia., Abrosimov AY; National Medical Research Center for Endocrinology, Ministry of Health of the Russian Federation, Moscow, Russia; National University of Science & Technology «MISIS», Moscow, Russia., Kuprash DV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia; Biological Faculty, Lomonosov Moscow State University, Moscow, Russia., Schwartz AM; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.

Publikováno v: Cancer letters [Cancer Lett] 2019 Dec 28; Vol. 467, pp. 96-106. Date of Electronic Publication: 2019 Jul 18.

Challenges in LC–MS-based metabolomics for Alzheimer's disease early detection: targeted approaches versus untargeted approaches.

Autor: Reveglia, Pierluigi¹ (AUTHOR), Paolillo, Carmela¹ (AUTHOR), Ferretti, Gabriella² (AUTHOR), De Carlo, Armando^1,3 (AUTHOR), Angiolillo, Antonella⁴ (AUTHOR), Nasso, Rosarita² (AUTHOR), Caputo, Mafalda⁵ (AUTHOR), Matrone, Carmela² (AUTHOR), Di Costanzo, Alfonso⁴ (AUTHOR), Corso, Gaetano^1,3 (AUTHOR) gaetano.corso@unifg.it

Publikováno v: Metabolomics. Sep2021, Vol. 17 Issue 9, p1-18. 18p.

How Does Citizen Science "Do" Governance? Reflections from the DITOs Project.

Autor: Göbel, Claudia¹, Nold, Christian², Berditchevskaia, Aleksandra³, Haklay, Mordechai²

Publikováno v: Citizen Science: Theory & Practice. 2019, Vol. 6 Issue 1, p1-13. 13p.

Impact of Genetic Risk Factors for Alzheimer's Disease on Brain Glucose Metabolism.

Autor: Cho S; Department of Brain and Cognitive Sciences, DGIST, Daegu, 42988, South Korea., Lee H; Department of Brain and Cognitive Sciences, DGIST, Daegu, 42988, South Korea., Seo J; Department of Brain and Cognitive Sciences, DGIST, Daegu, 42988, South Korea. jsseo@dgist.ac.kr.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2021 Jun; Vol. 58 (6), pp. 2608-2619. Date of Electronic Publication: 2021 Jan 21.