Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ramanathan Vaidyanathan"'
Autor:
Ramanathan Vaidyanathan, Shuvashis Dey, Andreas Behren, Matt Trau, Jing Wang, Abu Ali Ibn Sina, Alain Wuethrich, Zhaoran Wang, Ting-Yun Lin, Laura G. Carrascosa
Publikováno v:
Nanoscale Horizons. 5:1317-1323
Extracellular vesicles (EV) play a major role in intercellular communication by transmitting cellular materials (e.g. protein, RNA) among distant cells. Recent evidence suggests that they could also contribute to carrying DNA which could inform on th
Autor:
Sivaramapanicker Sreejith, Sook Yoong Chia, Ramanathan Vaidyanathan, Nagaendran Kandiah, Yi Jayne Tan, Adeline S.L. Ng, Li Zeng, Benjamin Y.X. Wong
Publikováno v:
Journal of Alzheimer's Disease Reports
Background: micro-RNAs (miRNAs) are stable, small, non-coding RNAs enriched in exosomes. Their variation in levels according to different disease etiologies have made them a promising diagnostic biomarker for neurodegenerative diseases such as Alzhei
Autor:
Shuvashis Dey, Jennifer R Tyler, Jing Wang, Hendrik J. Nel, Jamie Rossjohn, Matt Trau, Abu Ali Ibn Sina, Soi Cheng Law, Ramanathan Vaidyanathan, Yuling Wang, K. Kamil Reza, Hugh H. Reid, Ranjeny Thomas
Publikováno v:
Sensors and Actuators B: Chemical. 284:281-288
T-cells play a major role in host defense mechanisms against many diseases. With the current growth of immunotherapy approaches, there is a strong need for advanced technologies to detect and characterize these immune cells. Herein, we present a simp
Publikováno v:
Analytical and Bioanalytical Chemistry. 411:1311-1318
The development of a sensitive and specific detection platform for exosomes is highly desirable as they are believed to transmit vital tumour-specific information (mRNAs, microRNAs, and proteins) to remote cells for secondary metastasis. Herein, we r
Autor:
Yuanjin Zheng, Bengang Xing, Ramanathan Vaidyanathan, Sivaramapanicker Sreejith, Z. F. Wang, Li Zeng, Yen Peng Seah, Chwee Teck Lim, Rijil Thomas, Ata Abbas, Trifanny Yeo, Vivek Damodar Ranjan, Rahul Kishor
Publikováno v:
ACS Applied Materials & Interfaces. 11:4867-4875
Rapid surface functionalization of nanomaterials using covalent linkage following "green chemistry" remains challenging, and the quest for developing simple protocols is persisting. We report a nanomechanical microfluidic approach for the coupling of
Publikováno v:
Biotechnology Advances. 36:1367-1389
Circulating tumor cells (CTCs) and their clusters, also known as circulating tumor microemboli (CTM), have emerged as valuable tool that can provide mechanistic insights into the tumor heterogeneity, clonal evolution, and stochastic events within the
Autor:
Yadveer S. Grewal, Lachlan J. M. Coin, Minh Duc Cao, Stephen M. Mahler, Martina L. Jones, Christopher B. Howard, Darren Korbie, Matt Trau, Tania Duarte, Will Anderson, Lyndon J. Raftery, Ramanathan Vaidyanathan, Son Hoang Nguyen
Publikováno v:
Lab on a chip. 19(24)
Phage display methodologies offer a versatile platform for the isolation of single-chain Fv (scFv) molecules which may be rebuilt into monoclonal antibodies. Herein, we report on a complete workflow termed PhageXpress, for rapid selection of single-c
Autor:
Laura G. Carrascosa, Muhammad J. A. Shiddiky, Ramanathan Vaidyanathan, Matt Trau, Shuvashis Dey
Publikováno v:
ACS Sensors. 1:399-405
Profiling tumor cells present in blood based on multiple tumor-relevant markers can identify specific subpopulations of tumor cells and provide extensive information on the tumor status. Herein we present a simple approach for the analysis of tumor c
Publikováno v:
Lab on a chip. 19(1)
Technological advancements in research on circulating biomarkers from patient derived blood have enabled a less invasive means of diagnosing non-hematologic cancers. Considered a more practical way of real-time patient monitoring than traditional tum
Publikováno v:
Methods in cell biology. 147
The complexity and dynamic evolution of cancer often result in tumor subpopulations containing distinctly heterogeneous cells. During metastasis, these also give rise to heterogeneous circulating tumor cells (CTCs) which are considered to be a hemato