Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ramalingam Venkat Kalyana Sundaram"'
Autor:
Ramalingam Venkat Kalyana Sundaram, Manindra Bera, Jeff Coleman, Jonathan S. Weerakkody, Shyam S. Krishnakumar, Sathish Ramakrishnan
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany).
Cellular plasma membranes, in their role as gatekeepers to the external environment, host numerous protein assemblies and lipid domains that manage the movement of molecules into and out of cells, regulate electric potential, and direct cell signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46158fae67d8ceb3054bb763623f5cf0
https://pubmed.ncbi.nlm.nih.gov/36328714
https://pubmed.ncbi.nlm.nih.gov/36328714
Autor:
Ramalingam Venkat Kalyana Sundaram, Jeff Coleman, Shyam S. Krishnakumar, Feng Li, Sathish Ramakrishnan, Alberto T. Gatta, James E. Rothman, Frederic Pincet
Publikováno v:
FEBS Letters
FEBS Letters, Wiley, 2021, ⟨10.1002/1873-3468.14157⟩
FEBS Letters, Wiley, 2021, ⟨10.1002/1873-3468.14157⟩
International audience; Munc13-1 is a large banana-shaped soluble protein that is involved in the regulation of synaptic vesicle docking and fusion. Recent studies suggest that multiple copies of Munc13-1 form nanoassemblies in active zones of neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e481a9048cf707b85580610f612cab5e
https://hal.sorbonne-universite.fr/hal-03297036
https://hal.sorbonne-universite.fr/hal-03297036
Autor:
Tong Shu, Feng Li, Yongli Zhang, Ramalingam Venkat Kalyana Sundaram, Frederic Pincet, Shyam S. Krishnakumar, James E. Rothman, Jeff Coleman, Huaizhou Jin, Jie Yang
Publikováno v:
FEBS Letters
FEBS Letters, Wiley, 2021, 595, pp.297-309. ⟨10.1002/1873-3468.14006⟩
FEBS Lett
FEBS Letters, Wiley, 2021, 595, pp.297-309. ⟨10.1002/1873-3468.14006⟩
FEBS Lett
International audience; Synaptic vesicle fusion is mediated by SNARE proteins-VAMP2 on the vesicle and Syntaxin-1/ SNAP25 on the pre-synaptic membrane. Chaperones Munc18-1 and Munc13-1 cooperatively catalyze SNARE assembly via an intermediate 'templa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3f5e2f75d6b7b3512629c25c8c0ac1
https://hal.archives-ouvertes.fr/hal-03405619/document
https://hal.archives-ouvertes.fr/hal-03405619/document
Autor:
Prashanta Dutta, Y. M. Nuwan D. Y. Bandara, Irwin Chaiken, Armin Darvish, Jungsuk Kim, Gaurav Goyal, Ramalingam Venkat Kalyana Sundaram, Bin Peng, Jung Soo Lee, Jugal Saharia, Min Jun Kim, Chi Won Ahn
Publikováno v:
ELECTROPHORESIS. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6873bfacec40cf6a11a92b19f6fad6e7
https://doi.org/10.1002/elps.201970044
https://doi.org/10.1002/elps.201970044
Impact of HIV-1 Membrane Cholesterol on Cell-Independent Lytic Inactivation and Cellular Infectivity
Autor:
Huiyuan Li, Irwin Chaiken, Lauren D. Bailey, Ramalingam Venkat Kalyana Sundaram, Adel A. Rashad, Arangassery Rosemary Bastian, Karl Weiss, James Huynh, Steven P. Wrenn, Rachna Aneja, Elisabeth S. Papazoglou, Cameron F. Abrams
Publikováno v:
Biochemistry
Peptide triazole thiols (PTTs) have been found previously to bind to HIV-1 Env spike gp120 and cause irreversible virus inactivation by shedding gp120 and lytically releasing luminal capsid protein p24. Since the virions remain visually intact, lysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e45ce32cda3a01e40d53a4db387001c
https://doi.org/10.1021/acs.biochem.5b00936
https://doi.org/10.1021/acs.biochem.5b00936
Autor:
Gaurav Goyal, Irwin Chaiken, Jung Soo Lee, Y. M. Nuwan D. Y. Bandara, Ramalingam Venkat Kalyana Sundaram, Min Jun Kim, Jugal Saharia, Armin Darvish, Prashanta Dutta, Chi Won Ahn, Jungsuk Kim, Bin Peng
Publikováno v:
Electrophoresis
Enveloped viruses fuse with cells to transfer their genetic materials and infect the host cell. Fusion requires deformation of both viral and cellular membranes. Since the rigidity of viral membrane is a key factor in their infectivity, studying the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c052f681d7a64c2f714e8862a8844ec7
https://pubmed.ncbi.nlm.nih.gov/30151981
https://pubmed.ncbi.nlm.nih.gov/30151981
Autor:
Ramalingam Venkat Kalyana Sundaram, Adel A. Rashad, Caitlin Duffy, Rachna Aneja, Irwin Chaiken
Publikováno v:
Journal of Medicinal Chemistry. 58:7603-7608
We derived macrocyclic HIV-1 antagonists as a new class of peptidomimetic drug leads. Cyclic peptide triazoles (cPTs) retained the gp120 inhibitory and virus-inactivating signature of parent PTs, arguing that cyclization locked an active conformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2f7c9baa0402b3fbf369bc3b6737ba
https://doi.org/10.1021/acs.jmedchem.5b00935
https://doi.org/10.1021/acs.jmedchem.5b00935
Autor:
Kantharaju Kamanna, Irwin Chaiken, Ramalingam Venkat Kalyana Sundaram, Charles G. Ang, Caitlin Duffy, Yu-Hung Huang, Karyn McFadden, Arangassery Rosemary Bastian, Farida Shaheen, Lauren D. Bailey
Publikováno v:
Virus research. 235
HIV-1 Env protein is essential for host cell entry, and targeting Env remains an important antiretroviral strategy. We previously found that a peptide triazole thiol KR13 and its gold nanoparticle conjugate AuNP-KR13 directly and irreversibly inactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2edcfeba0943266bbf302d36873484
https://pubmed.ncbi.nlm.nih.gov/28390972
https://pubmed.ncbi.nlm.nih.gov/28390972
Autor:
Petia M. Vlahovska, Rachna Aneja, Gaurav Goyal, Ramalingam Venkat Kalyana Sundaram, Min Jun Kim, Chi Won Ahn, Armin Darvish, Ki-Bum Kim, Kidan Lee
Publikováno v:
Nanoscale. 8(30)
Solid-state nanopores have been widely used in the past for single-particle analysis of nanoparticles, liposomes, exosomes and viruses. The shape of soft particles, particularly liposomes with a bilayer membrane, can greatly differ inside the nanopor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa115955730b6c40381ea683ee27647d
https://pubmed.ncbi.nlm.nih.gov/27321911
https://pubmed.ncbi.nlm.nih.gov/27321911
Autor:
Michael G. Schrlau, Zulfiya Orynbayeva, Ramalingam Venkat Kalyana Sundaram, Gary Friedman, Sayan Bhattacharyya, Elina A. Vitol, Elisabeth S. Papazoglou, Riju Singhal, Junjie Niu, Yury Gogotsi
Publikováno v:
Nature Nanotechnology. 6:57-64
Glass micropipettes, atomic force microscope tips and nanoneedles can be used to interrogate cells, but these devices either have conical geometries that can damage cells during penetration or are incapable of continuous fluid handling. Here, we repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34da1e729e32ecbae202fbfaca8cf766
https://doi.org/10.1038/nnano.2010.241
https://doi.org/10.1038/nnano.2010.241