Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ramakrishnan Melarkode"'
Autor:
Anushikha Thakur, Rekha Nagpal, Avik Kumar Ghosh, Deepak Gadamshetty, Sirisha Nagapattinam, Malini Subbarao, Shreshtha Rakshit, Sneha Padiyar, Suma Sreenivas, Nagaraja Govindappa, Harish V. Pai, Ramakrishnan Melarkode Subbaraman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
Abstract Sequence variants (SV) in protein bio therapeutics can be categorized as unwanted impurities and may raise serious concerns in efficacy and safety of the product. Early detection of specific sequence modifications, that can result in altered
Externí odkaz:
https://doaj.org/article/5e77fcb98c3d4da6a2b92852977e8e65
Autor:
Parag Goyal, Harish Venkatraman Pai, Phanichand Kodali, Bhavesh Vats, Navratna Vajpai, Shankara Annegowda, Krishnappa Mane, Shamini Mohan, Shruti Saxena, Anil Bangalore Veerabhadraia, Milee Palande, Preethy Sasankan Nair, Digvijay Chandrashekar More, Umamaheshwara Rao Karudumpa, Kunala Jyothirmai, Adroha Bhattacharya, Frida Almeida, Santosh Gulab Khyade, Shankara Gouda, Daniel J Ranayhossaini, Praveen Reddy Moole, Jeffrey P Smith, Abhijit Barve, Ramakrishnan Melarkode, Rajesh Ullanat
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253168 (2021)
Insulin glargine is a long-acting analogue of human insulin that has been used to manage hyperglycemia in patients with diabetes mellitus (DM) for nearly 20 years. Insulin glargine has a relatively constant concentration-time profile that mimics basa
Externí odkaz:
https://doaj.org/article/6da37cf349e544349ce158046d965d25
Autor:
Anushikha Thakur, Rekha Nagpal, Avik Kumar Ghosh, Deepak Gadamshetty, Sirisha Nagapattinam, Malini Subbarao, Shreshtha Rakshit, Sneha Padiyar, Suma Sreenivas, Nagaraja Govindappa, Harish V. Pai, Ramakrishnan Melarkode Subbaraman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/81ea75bf02d5412797c0e4ff82e64134
Autor:
Usha Bughani, Arindam Saha, Anshu Kuriakose, Reshmi Nair, Ravindra B Sadashivarao, Rasika Venkataraman, Swati Patel, Anuja Tushar Deshchougule, Kumar S Satish, Enrique Montero, Harish V Pai, Dinesh V Palanivelu, Ramakrishnan Melarkode, Pradip Nair
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0192335 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0180088.].
Externí odkaz:
https://doaj.org/article/1c22fa488f94401a8e39af0a7fad63fe
Autor:
Usha Bughani, Arindam Saha, Anshu Kuriakose, Reshmi Nair, Ravindra B Sadashivarao, Rasika Venkataraman, Swati Patel, Anuja Tushar Deshchougule, Satish Kumar S, Enrique Montero, Harish V Pai, Dinesh V Palanivelu, Ramakrishnan Melarkode, Pradip Nair
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180088 (2017)
CD6 is associated with T-cell modulation and is implicated in several autoimmune diseases. We previously demonstrated that Itolizumab, a CD6 domain 1 (CD6D1) specific humanized monoclonal antibody, inhibited the proliferation and cytokine production
Externí odkaz:
https://doaj.org/article/c65b7916659142f78e52a699d7aa8db6
Autor:
Namrata Shastri, Shulagna Sharma, Anushikha Thakur, H. Pai, Arnab Bera, Ramakrishnan Melarkode, Shankara Annegowda, Sneha Trivedi, Deepa Mohan, Abhilashi Sahu, Pradip Nair, Sheija Rohil, Pradeep Kabadi, Ranitendranath Tagore, Rajesh Ullanat, Malini Subbarao, Roshni Thomas, Gaurav R Mehta, Parag Goyal, Roopa Venkatachala, Bhavesh Vats, Chethan Gejjalagere Honnappa, Yatika Gokhale, Umamaheshwara Rao K, Laxmi Adhikari
Publikováno v:
Expert Opinion on Biological Therapy. 22:271-298
BACKGROUND Bevacizumab (BEV) is a recombinant humanized monoclonal immunoglobulin G1 antibody that binds to vascular endothelial growth factor (VEGF)-A and acts as an antiangiogenic agent. It is approved for treatment of many cancer indications, incl
Autor:
Arnab Bera, Jeffrey Smith, Bhavesh Vats, Daniel J. Ranayhossaini, Rajesh Ullanat, H. Pai, Gaurav R Mehta, Pradeep Kabadi, Ankita Singh, Praveen Reddy Moole, Abhilashi Sahu, Ramakrishnan Melarkode, Maninder Kaur, Malini Subbarao, Parag Goyal, Laxmi Adhikary, Jyoti Iyer, Shankara Gouda, Arindam Saha, Ashwani Marwah
Publikováno v:
Future Medicinal Chemistry. 13:1531-1557
Aims: Preclinical comparative similarity studies of trastuzumab-dkst, a Herceptin® biosimilar, are reported. Materials & methods: Primary sequence and higher order structure and pharmacological mechanisms of action were compared using multiple techn
Autor:
Shreshtha Rakshit, Ramakrishnan Melarkode Subbaraman, Suma Sreenivas, Sneha Padiyar, Anushikha Thakur, Malini Subbarao, Sirisha Nagapattinam, Rekha Nagpal, H. Pai, Deepak Gadamshetty, Nagaraja Govindappa, Avik Kumar Ghosh
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
Sequence variants (SV) in protein bio therapeutics can be categorized as unwanted impurities and may raise serious concerns in efficacy and safety of the product. Early detection of specific sequence modifications, that can result in altered physicoc
Autor:
Daniel J. Ranayhossaini, Santosh Gulab Khyade, Umamaheshwara Rao Karudumpa, Digvijay Chandrashekar More, Bhavesh Vats, Preethy Sasankan Nair, Ramakrishnan Melarkode, Kunala Jyothirmai, Adroha Bhattacharya, Shankara Gouda, Jeffrey P. Smith, Krishnappa Mane, Shamini Mohan, Praveen Reddy Moole, Abhijit Barve, H. Pai, Shankara Annegowda, Navratna Vajpai, Frida Almeida, Anil Bangalore Veerabhadraia, Milee Palande, Parag Goyal, Shruti Saxena, Phanichand Kodali, Rajesh Ullanat
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0253168 (2021)
PLoS ONE, Vol 16, Iss 6, p e0253168 (2021)
Insulin glargine is a long-acting analogue of human insulin that has been used to manage hyperglycemia in patients with diabetes mellitus (DM) for nearly 20 years. Insulin glargine has a relatively constant concentration-time profile that mimics basa
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