Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ramakrishna Dumpati"'
Autor:
Vishwanath Ramatenki, Uma Vuruputuri, Ramakrishna Dumpati, Sarita Rajender Potlapally, Santhiprada Vellanki, Rajender Vadija, Rohini Rondla
Publikováno v:
Applied Biochemistry and Biotechnology. 182:1497-1517
Cancer is characterized by abnormal growth of cells. Targeting ubiquitin proteins in the discovery of new anticancer therapeutics is an attractive strategy. The present study uses the structure-based drug discovery methods to identify new lead struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261b221cb0d6abf3b098fa536b055d72
https://doi.org/10.1007/s12010-017-2414-7
https://doi.org/10.1007/s12010-017-2414-7
Autor:
Ramasree Dulapalli, Bhargavi Kondagari, Ramakrishna Dumpati, Santhiprada Vellanki, Uma Vuruputuri, Vishwanath Ramatenki, Rajender Vadija
Publikováno v:
ChemistrySelect. 1:2502-2514
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17fb2006e3e8f7c82cca981bcf89c450
https://doi.org/10.1002/slct.201600640
https://doi.org/10.1002/slct.201600640
Autor:
Uma Vuruputuri, Vishwanath Ramatenki, Rajender Vadija, Navaneetha Nambigari, Ramasree Dulapalli, Ramakrishna Dumpati, Santhi Prada Vellanki, Kiran Kumar Mustyala
Publikováno v:
Journal of Chemical Biology. 9:69-78
Keratinocyte growth factor (KGF) protein is a member of the fibroblast growth factor (FGF) family, which is also known as FGF-7. The FGF-7 plays an important role in tumor angiogenesis. In the present work, FGF-7 is treated as a potential therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d26fe9df82ffa2b497ea39b46d10585
https://doi.org/10.1007/s12154-016-0152-x
https://doi.org/10.1007/s12154-016-0152-x
Autor:
Vishwanath Ramatenki, Ramakrishna Dumpati, Santhiprada Vellanki, Uma Vuruputuri, Rajender Vadija
Publikováno v:
Journal of molecular recognition : JMR. 31(7)
The study considers the Suppressor of cytokine signaling 1 (SOCS1) protein as a novel Type 2 diabetes mellitus (T2DM) drug target. T2DM in human beings is also triggered by the over expression of SOCS proteins. The SOCS1 acts as a ubiquitin ligase (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a54d30750f3c92967a1b6d3d775ea7
https://pubmed.ncbi.nlm.nih.gov/29630758
https://pubmed.ncbi.nlm.nih.gov/29630758
Targeting the ubiquitin-conjugating enzyme E2D4 for cancer drug discovery-a structure-based approach
Autor:
Rohini Rondla, Sarita Rajender Potlapally, Santhiprada Vellanki, Ramakrishna Dumpati, Rajender Vadija, Uma Vuruputuri, Vishwanath Ramatenki
Publikováno v:
Journal of chemical biology. 10(2)
Cancer progression is a global burden. The incidence and mortality now reach 30 million deaths per year. Several pathways of cancer are under investigation for the discovery of effective therapeutics. The present study highlights the structural detai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa9c00a9f6595d71c530e52a0aa1be2
https://pubmed.ncbi.nlm.nih.gov/28405240
https://pubmed.ncbi.nlm.nih.gov/28405240
Autor:
Uma Vuruputuri, Ramasree Dulapalli, Bhargavi Kondagari, Ramakrishna Dumpati, Vishwanath Ramatenki, Rajender Vadija, Navaneetha Nambigari, Santhi Prada Vellanki
Publikováno v:
Interdisciplinary sciences, computational life sciences. 10(2)
The Human Chemokine (C-C motif) ligand 19 (CCL19) protein plays a major role in rheumatic and autoimmune diseases. The 3D models of the CCL19 and its receptor CCR7 are generated using homology modeling and are validated using standard computational p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680f2058e2d9be3d9a701310f5f93dde
https://pubmed.ncbi.nlm.nih.gov/28271460
https://pubmed.ncbi.nlm.nih.gov/28271460