Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ramadevi Sanam"'
Publikováno v:
Bioinformation
In this study, chemical feature based pharmacophore models of MMP-1, MMP-8 and MMP-13 inhibitors have been developed with the aid of HypoGen module within Catalyst program package. In MMP-1 and MMP-13, all the compounds in the training set mapped HBA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efcbc72fd0337f5c926abf802926c840
http://europepmc.org/articles/PMC3338973
http://europepmc.org/articles/PMC3338973
Autor:
Raveendra Dayam, Rambabu Gundla, Lakshmi Narasu, S. Vadivelan, Ramadevi Sanam, Nouri Neamati, Pavan Kumar Machiraju, Sarma A.R.P. Jagarlapudi, Sunita Tajne
Publikováno v:
Journal of Molecular Graphics and Modelling. 28:472-477
Heat Shock Protein 90 (HSP90), an ATP-dependent molecular chaperone, has emerged as a promising target in the treatment of cancer. Inhibition of HSP90 represents a new target of antitumor therapy, since it may influence many specific signaling pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f89ea30cd3ec534e1d1cfd7365b406
https://doi.org/10.1016/j.jmgm.2009.11.002
https://doi.org/10.1016/j.jmgm.2009.11.002
Autor:
S. Vadivelan, Ramadevi Sanam, Sunita Tajne, G. Rambabu, Sarma A.R.P. Jagarlapudi, Lakshmi Narasu
Publikováno v:
European Journal of Medicinal Chemistry. 44:4793-4800
The best ZAP-70 inhibitor model consists of four-pharmacophore features, (1) one hydrogen bond acceptor, (2) one hydrogen bond donor (3) one hydrophobic aliphatic and (4) one hydrophobic aromatic features. This model was validated against 110 known Z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36364b714de0b643519494ba66603f28
https://doi.org/10.1016/j.ejmech.2009.07.018
https://doi.org/10.1016/j.ejmech.2009.07.018
Autor:
Nouri Neamati, Jagarlapudi A. R. P. Sarma, Raveendra Dayam, Ramadevi Sanam, Ravikumar Muttineni, Roza Kazemi, Rambabu Gundla
Publikováno v:
Journal of Medicinal Chemistry. 51:3367-3377
Consensus virtual screening models were generated and validated utilizing a set of known human epidermal growth factor receptor-2 (HER2) inhibitors and modeled HER2 active and inactive state structures. The virtual screening models were successfully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492fb472fc163a28bcb22f7753aaf412
https://doi.org/10.1021/jm7013875
https://doi.org/10.1021/jm7013875
Autor:
Maheedhara R. Guda, Sarah E. Martin, David J. Daniels, Ramadevi Sanam, Collin M. Labak, Julian J. Lin, Andrew J. Tsung, Jose R. Castellanos, Swapna Asuthkar, Kiran Kumar Velpula
Publikováno v:
Cancer Research. 77:2004-2004
Medulloblastoma (MB) is the most common malignant brain tumor in children and accounts for 20% of pediatric CNS tumors. Following surgery and treatment with chemotherapy and radiation, MBs recur in a significant proportion of patients. Moreover, surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05d2f1e4c35554d67cb24ecfee2bba22
https://doi.org/10.1158/1538-7445.am2017-2004
https://doi.org/10.1158/1538-7445.am2017-2004
Autor:
Soumya Chigurupati, Krishna Kishore Inampudi, Azeem A. Rehman, Chandra Sekhar Akila, Ramadevi Sanam, Kiran Kumar Velpula
Publikováno v:
Bioinformation
CREB3L4 is a member of the CREB/ATF transcription factor family, characterized by their regulation of gene expression through the cAMP-responsive element. Previous studies identified this protein in mice and humans. Whereas CREB3L4 in mice (referred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b191cdeafd27c4d710bfce6c2833d15
https://pubmed.ncbi.nlm.nih.gov/22829733
https://pubmed.ncbi.nlm.nih.gov/22829733
Autor:
Dayakar Boddupally, Rambabu Gundla, Ramadevi Sanam, Dashavantha Reddy Vudem, Neha S. Gandhi, Ricardo L. Mancera, Venkateswara Rao Khareedu, Sunita Tajne
Publikováno v:
Journal of molecular graphicsmodelling. 33
Genetic engineering of Bacillus thuringiensis (Bt) Cry proteins has resulted in the synthesis of various novel toxin proteins with enhanced insecticidal activity and specificity towards different insect pests. In this study, a fusion protein consisti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb0e5ccd9d1702b07f2d70f5323c068
https://pubmed.ncbi.nlm.nih.gov/22182469
https://pubmed.ncbi.nlm.nih.gov/22182469
Autor:
Rambabu Gundla, Roza Kazemi, Ramadevi Sanam, Ravikumar Muttineni, Jagarlapudi A. R. P. Sarma, Raveendra Dayam, Nouri Neamati
Publikováno v:
Journal of Medicinal Chemistry; May2008, Vol. 51 Issue 12, p3367-3377, 11p