Zobrazeno 1 - 10
of 1 361
pro vyhledávání: '"Ramachandran S. Vasan"'
Autor:
Aya Awwad, Eugene P. Rhee, Morgan Grams, Hernan Rincon Choles, James Sondheimer, Jiang He, Jing Chen, Chi-yuan Hsu, Ramachandran S Vasan, Paul L. Kimmel, Kendra Wulczyn, Anders Berg, Jim Lash, Mengyao Tang, Sahir Kalim, the CRIC Study Investigators
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Protein carbamylation, a post-translational protein modification primarily driven by urea, independently associates with adverse clinical outcomes in patients with CKD. Biomarkers used to quantify carbamylation burden have mainly
Externí odkaz:
https://doaj.org/article/9b4ad286cc1e46068593b66e1033a4ab
Autor:
Rebecca Keener, Surya B. Chhetri, Carla J. Connelly, Margaret A. Taub, Matthew P. Conomos, Joshua Weinstock, Bohan Ni, Benjamin Strober, Stella Aslibekyan, Paul L. Auer, Lucas Barwick, Lewis C. Becker, John Blangero, Eugene R. Bleecker, Jennifer A. Brody, Brian E. Cade, Juan C. Celedon, Yi-Cheng Chang, L. Adrienne Cupples, Brian Custer, Barry I. Freedman, Mark T. Gladwin, Susan R. Heckbert, Lifang Hou, Marguerite R. Irvin, Carmen R. Isasi, Jill M. Johnsen, Eimear E. Kenny, Charles Kooperberg, Ryan L. Minster, Take Naseri, Satupa’itea Viali, Sergei Nekhai, Nathan Pankratz, Patricia A. Peyser, Kent D. Taylor, Marilyn J. Telen, Baojun Wu, Lisa R. Yanek, Ivana V. Yang, Christine Albert, Donna K. Arnett, Allison E. Ashley-Koch, Kathleen C. Barnes, Joshua C. Bis, Thomas W. Blackwell, Eric Boerwinkle, Esteban G. Burchard, April P. Carson, Zhanghua Chen, Yii-Der Ida Chen, Dawood Darbar, Mariza de Andrade, Patrick T. Ellinor, Myriam Fornage, Bruce D. Gelb, Frank D. Gilliland, Jiang He, Talat Islam, Stefan Kaab, Sharon L. R. Kardia, Shannon Kelly, Barbara A. Konkle, Rajesh Kumar, Ruth J. F. Loos, Fernando D. Martinez, Stephen T. McGarvey, Deborah A. Meyers, Braxton D. Mitchell, Courtney G. Montgomery, Kari E. North, Nicholette D. Palmer, Juan M. Peralta, Benjamin A. Raby, Susan Redline, Stephen S. Rich, Dan Roden, Jerome I. Rotter, Ingo Ruczinski, David Schwartz, Frank Sciurba, M. Benjamin Shoemaker, Edwin K. Silverman, Moritz F. Sinner, Nicholas L. Smith, Albert V. Smith, Hemant K. Tiwari, Ramachandran S. Vasan, Scott T. Weiss, L. Keoki Williams, Yingze Zhang, Elad Ziv, Laura M. Raffield, Alexander P. Reiner, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Hematology and Hemostasis Working Group, TOPMed Structural Variation Working Group, Marios Arvanitis, Carol W. Greider, Rasika A. Mathias, Alexis Battle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Genome-wide association studies (GWAS) have become well-powered to detect loci associated with telomere length. However, no prior work has validated genes nominated by GWAS to examine their role in telomere length regulation. We conducted a
Externí odkaz:
https://doaj.org/article/3e293e6c932a4a42b553d789d690044b
Autor:
Yuankai Zhang, Xuzhi Wang, Chathurangi H Pathiravasan, Nicole L Spartano, Honghuang Lin, Belinda Borrelli, Emelia J Benjamin, David D McManus, Martin G Larson, Ramachandran S Vasan, Ravi V Shah, Gregory D Lewis, Chunyu Liu, Joanne M Murabito, Matthew Nayor
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e56676 (2024)
BackgroundResting heart rate (HR) and routine physical activity are associated with cardiorespiratory fitness levels. Commercial smartwatches permit remote HR monitoring and step count recording in real-world settings over long periods of time, but t
Externí odkaz:
https://doaj.org/article/e9e5182e9c70429c97c986c03547143c
Autor:
Jonathan G. Amatruda, Ronit Katz, Casey M. Rebholz, Mark J. Sarnak, Orlando M. Gutierrez, Sarah J. Schrauben, Jason H. Greenberg, Josef Coresh, Mary Cushman, Sushrut Waikar, Chirag R. Parikh, Jeffrey R. Schelling, Manasi P. Jogalekar, Joseph V. Bonventre, Ramachandran S. Vasan, Paul L. Kimmel, Joachim H. Ix, Michael G. Shlipak
Publikováno v:
Kidney Medicine, Vol 6, Iss 6, Pp 100834- (2024)
Rationale & Objective: Tubulointerstitial damage is a feature of early chronic kidney disease (CKD), but current clinical tests capture it poorly. Urine biomarkers of tubulointerstitial health may identify risk of CKD. Study Design: Prospective cohor
Externí odkaz:
https://doaj.org/article/6c30c18def6e45a6aa01ef19841e1239
Autor:
Rebecca J. Song, Martin G. Larson, Hugo J. Aparicio, J. Michael Gaziano, Peter Wilson, Kelly Cho, Ramachandran S. Vasan, Matthew P. Fox, Luc Djoussé, On Behalf Of the Million Veteran Program
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background There is inconsistent evidence on the association of moderate alcohol consumption and stroke risk in the general population and is not well studied among U.S. Veterans. Furthermore, it is unclear whether primarily drinking beer, w
Externí odkaz:
https://doaj.org/article/041e15c4536e4261b60d9509ea8afa7a
Autor:
Amalie Lykkemark Møller, Ramachandran S. Vasan, Daniel Levy, Charlotte Andersson, Honghuang Lin
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Gene function can be described using various measures. We integrated association studies of three types of omics data to provide insights into the pathophysiology of subclinical coronary disease and myocardial infarction (MI). Using multivar
Externí odkaz:
https://doaj.org/article/c05cd67a155c4e31975f59346a1ecc65
Autor:
Sandhiya Ravichandran, Priya Gajjar, Maura E. Walker, Brenton Prescott, Connie W. Tsao, Mawra Jha, Prashant Rao, Patricia Miller, Martin G. Larson, Ramachandran S. Vasan, Ravi V. Shah, Vanessa Xanthakis, Gregory D. Lewis, Matthew Nayor
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background The relation of cardiorespiratory fitness (CRF) to lifestyle behaviors and factors linked with cardiovascular health remains unclear. We aimed to understand how the American Heart Association's Life's Essential 8 (LE8) score (and its chang
Externí odkaz:
https://doaj.org/article/a8330f7ca0a44f87a7f4dc1a2b839653
Autor:
Xuzhi Wang, Yuankai Zhang, Chathurangi H Pathiravasan, Nene C Ukonu, Jian Rong, Emelia J Benjamin, David D McManus, Martin G Larson, Ramachandran S Vasan, Naomi M Hamburg, Joanne M Murabito, Chunyu Liu, Gary F Mitchell
Publikováno v:
JMIR Cardio, Vol 8, p e54801 (2024)
BackgroundShort-term blood pressure variability (BPV) is associated with arterial stiffness in patients with hypertension. Few studies have examined associations between arterial stiffness and digital home BPV over a mid- to long-term time span, irre
Externí odkaz:
https://doaj.org/article/09999f0f3f80430f9aef7c4ab1b43faa
Autor:
Adrienne Tin, Alison E. Fohner, Qiong Yang, Jennifer A. Brody, Gail Davies, Jie Yao, Dan Liu, Ilana Caro, Joni V. Lindbohm, Michael R. Duggan, Osorio Meirelles, Sarah E. Harris, Valborg Gudmundsdottir, Adele M. Taylor, Albert Henry, Alexa S. Beiser, Ali Shojaie, Annabell Coors, Annette L. Fitzpatrick, Claudia Langenberg, Claudia L. Satizabal, Colleen M. Sitlani, Eleanor Wheeler, Elliot M. Tucker-Drob, Jan Bressler, Josef Coresh, Joshua C. Bis, Julián Candia, Lori L. Jennings, Maik Pietzner, Mark Lathrop, Oscar L. Lopez, Paul Redmond, Robert E. Gerszten, Stephen S. Rich, Susan R. Heckbert, Thomas R. Austin, Timothy M. Hughes, Toshiko Tanaka, Valur Emilsson, Ramachandran S. Vasan, Xiuqing Guo, Yineng Zhu, Christophe Tzourio, Jerome I. Rotter, Keenan A. Walker, Luigi Ferrucci, Mika Kivimäki, Monique M. B. Breteler, Simon R. Cox, Stephanie Debette, Thomas H. Mosley, Vilmundur G. Gudnason, Lenore J. Launer, Bruce M. Psaty, Sudha Seshadri, Myriam Fornage
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Identifying circulating proteins associated with cognitive function may point to biomarkers and molecular process of cognitive impairment. Few studies have investigated the association between circulating proteins and cognitive function. We
Externí odkaz:
https://doaj.org/article/8eb6e400abed4b8eba3c10d3a6a5024b
Autor:
Ruth F. Dubin, Rajat Deo, Yue Ren, Jianqiao Wang, Zihe Zheng, Haochang Shou, Alan S. Go, Afshin Parsa, James P. Lash, Mahboob Rahman, Chi-yuan Hsu, Matthew R. Weir, Jing Chen, Amanda Anderson, Morgan E. Grams, Aditya Surapaneni, Josef Coresh, Hongzhe Li, Paul L. Kimmel, Ramachandran S. Vasan, Harold Feldman, Mark R. Segal, Peter Ganz, CRIC Study Investigators, CKD Biomarkers Consortium
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Progression of chronic kidney disease (CKD) portends myriad complications, including kidney failure. In this study, we analyze associations of 4638 plasma proteins among 3235 participants of the Chronic Renal Insufficiency Cohort Study with
Externí odkaz:
https://doaj.org/article/e4b35c37bd9f4b68928efff3e22388ac