Zobrazeno 1 - 6
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pro vyhledávání: '"Ramachandran Krishna Chandran"'
Autor:
Ramachandran Krishna Chandran, Narayanan Geetha, Kunnathur Murugesan Sakthivel, Raveendran Suresh Kumar, Kumarapillai Mohanan Nair Jagathnath Krishna, Hariharan Sreedharan
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The emergence of additional chromosomal abnormalities (ACAs) in Philadelphia chromosome/BCR-ABL1 positive chronic myeloid leukemia (CML), is considered to be a feature of disease evolution. However, their frequency of incidence, impact on prognosis a
Externí odkaz:
https://doaj.org/article/6d051bd32026448ca60a16ea3d437225
Autor:
Narayanan Geetha, Kumarapillai Mohanan Nair Jagathnath Krishna, Kunnathur Murugesan Sakthivel, Hariharan Sreedharan, Thampirajan Vimaladevi Akhila Raj, Ramachandran Krishna Chandran
Publikováno v:
Journal of Environmental Pathology, Toxicology and Oncology. 40:51-64
The clinical implications of cohesin gene complex mutation in acute myeloid leukemia (AML) are not well characterized. In the present study, a cohort of 152 de novo unselected adult AML patients underwent conventional and molecular cytogenetic analys
Autor:
Narayanan Geetha, Ramachandran Krishna Chandran, Raveendran Suresh Kumar, Kumarapillai Mohanan Nair Jagathnath Krishna, Kunnathur Murugesan Sakthivel, Hariharan Sreedharan
Publikováno v:
Blood Cells, Molecules, and Diseases. 77:51-60
The molecular mechanisms responsible for disease progression of CML are not conclusive. The main functional changes associated with disease evolution in CML was high proliferation rate, decreased apoptosis, blockade of differentiation, and strong res
Autor:
Preethi Gopinath, Thampirajan Vimaladevi Akhila Raj, Kunnathur Murugesan Sakthivel, Jagathnath Krishna Kumarapillai Mohanan Nair, Ramachandran Krishna Chandran, Hariharan Sreedharan, Geetha Priya, Narayanan Geetha, Chandran Geetha Aswathy
Publikováno v:
Gene. 686:85-91
Identification of BCR-ABL1 fusion gene amplification status is critically important in the effective management of chronic myelogenous leukemia (CML) patients. Earlier reports suggested that overexpression of BCR-ABL1 either through amplification of
Autor:
Ramachandran Krishna Chandran, Narayanan Geetha, Kunnathur Murugesan Sakthivel, Raveendran Suresh Kumar, Kumarapillai Mohanan Nair Jagathnath Krishna, Hariharan Sreedharan
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology, Vol 9 (2019)
The emergence of additional chromosomal abnormalities (ACAs) in Philadelphia chromosome/BCR-ABL1 positive chronic myeloid leukemia (CML), is considered to be a feature of disease evolution. However, their frequency of incidence, impact on prognosis a
Autor:
Kunnathur Murugesan Sakthivel, Preethi Gopinath, Narayanan Geetha, Ramachandran Krishna Chandran, Chandran Geetha Aswathy, Hariharan Sreedharan, Jagathnath Krishna Kumarapillai Mohanan Nair
Publikováno v:
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 37(2)
Elucidation of cryptic BCR/ABL1 gene rearrangement is exceptionally important in the clinical diagnosis and prognosis of chronic myelogenous leukemia (CML). Previous reports indicated an adverse prognostic effect of atypical BCR/ABL1 gene rearrangeme