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Autor:
Vijay Nair, Anakkalil Ramachandran Sreekanth, Narayana Pillai Abhilash, Akkattu Thankappan Nair Biju, Luxmi Varma, Sreemathi Viji, Saumini Mathew
Publikováno v:
ARKIVOC, Vol 2005, Iss 11, Pp 178-188 (2005)
Externí odkaz:
https://doaj.org/article/60eb5c2b779d4fe6a18919b1a29dbec6
Autor:
Ashu Gupta, Son Minh Pham, Ramachandran Sreekanth A, Sebastian Belmar, Francisco J. Herrera, Iván E. Alfaro, Mohd. Raja, Pradeep S. Jadhavar, Anil Agarwal, Deepak P. Kalane, Sebastian Bernales, Siddhartha Singh, Kakoli Mukherjee, Kevin P. Quinn, Sathe Balaji Dashrath, Roopa Rai, Sandeep K. Miglani, Christopher Higgs, Srijan Haldar, Manvendra Singh, Sarvajit Chakravarty
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:2153-2160
Signaling via the receptor tyrosine kinase CSF1R is thought to play an important role in recruitment and differentiation of tumor-associated macrophages (TAMs). TAMs play pro-tumorigenic roles, including the suppression of anti-tumor immune response,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4248025b5b6e0c61bc10ba9a742d7021
https://doi.org/10.1016/j.bmcl.2017.03.064
https://doi.org/10.1016/j.bmcl.2017.03.064
Autor:
Ramachandran, Sreekanth A., Jadhavar, Pradeep S., Miglani, Sandeep K., Singh, Manvendra P., Kalane, Deepak P., Agarwal, Anil K., Sathe, Balaji D., Mukherjee, Kakoli, Gupta, Ashu, Haldar, Srijan, Raja, Mohd, Singh, Siddhartha, Pham, Son M., Chakravarty, Sarvajit, Quinn, Kevin, Belmar, Sebastian, Alfaro, Ivan E., Higgs, Christopher, Bernales, Sebastian, Herrera, Francisco J., Rai, Roopa
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 15 May 2017 27(10):2153-2160
Autor:
Ramachandran, Sreekanth A., Jadhavar, Pradeep S., Singh, Manvendra P., Sharma, Ankesh, Bagle, Gaurav N., Quinn, Kevin P., Wong, Po-yin, Protter, Andrew A., Rai, Roopa, Pham, Son M., Lindquist, Jeffrey N.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 15 February 2017 27(4):750-754
Autor:
Parvinder Kaur, Anisha Ambady, Sreevalli Sharma, Vinayak Hosagrahara, Ashwini Narayan, Vasanthi Ramachandran, Suresh Rudrapatna, Supreeth Guptha, Pravin S. Shirude, Vasan K. Sambandamurthy, Jyothi Mahadevaswamy, Ramachandran Sreekanth A, Kavitha Nagalapur, Anandkumar Raichurkar, Naina Hegde, Manoranjan Panda, Vaishali Humnabadkar
Publikováno v:
Journal of Medicinal Chemistry. 57:4761-4771
A novel pyrazolopyridone class of inhibitors was identified from whole cell screening against Mycobacterium tuberculosis (Mtb). The series exhibits excellent bactericidality in vitro, resulting in a 4 log reduction in colony forming units following c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccaf74e3eb5da053234d8a4086719c71
https://doi.org/10.1021/jm5002937
https://doi.org/10.1021/jm5002937
Autor:
Nilanjana Roy Choudhury, Balachandra Bandodkar, Vasanthi Ramachandran, Ramachandran Sreekanth A, Chaitanya Kumar Kedari, Kakoli Mukerjee, Parvinder Kaur, Manoranjan Panda, Supreeth Guptha, Sreevalli Sharma, Subramanyam J. Tantry
Publikováno v:
ACS Medicinal Chemistry Letters. 5:491-495
A whole cell based screening effort on a focused library from corporate collection resulted in the identification of biarylmethoxy nicotinamides as novel inhibitors of M. tuberculosis (Mtu) H37Rv. The series exhibited tangible structure–activity re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379f4ad218219ad2f8fcc0dea9407917
https://doi.org/10.1021/ml4004815
https://doi.org/10.1021/ml4004815
Autor:
Ankesh Sharma, Po-yin Wong, Kevin P. Quinn, Andrew A. Protter, Roopa Rai, Son Minh Pham, Manvendra Singh, Ramachandran Sreekanth A, Pradeep S. Jadhavar, Gaurav N. Bagle, Jeffrey N. Lindquist
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(4)
The ATR pathway is a critical mediator of the replication stress response in cells. In aberrantly proliferating cancer cells, this pathway can help maintain sufficient genomic integrity for cancer cell progression. Herein we describe the discovery of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3979185fa7900f8641063a59d8be9247
https://pubmed.ncbi.nlm.nih.gov/28131712
https://pubmed.ncbi.nlm.nih.gov/28131712
Autor:
Jadhavar, Pradeep S., Ramachandran, Sreekanth A., Riquelme, Eduardo, Gupta, Ashu, Quinn, Kevin P., Shivakumar, Devleena, Ray, Soumya, Zende, Dnyaneshwar, Nayak, Anjan K., Miglani, Sandeep K., Sathe, Balaji D., Raja, Mohd., Farias, Olivia, Alfaro, Ivan, Belmar, Sebastián, Guerrero, Javier, Bernales, Sebastián, Chakravarty, Sarvajit, Hung, David T., Lindquist, Jeffrey N., Rai, Roopa
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 November 2016 26(21):5222-5228
Autor:
Vasanthi Ramachandran, Manoranjan Panda, Vasan K. Sambandamurthy, Subramanyam J. Tantry, Nilanjana Roy Choudhury, Kakoli Mukherjee, Ramachandran Sreekanth A, Supreeth Guptha, Chaitanya Kumar Kedari, Sreevalli Sharma, V. K. Ramya
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:4996-5001
Imidazo[1,2-a]pyridine-8-carboxamides as a novel antimycobacterial lead were generated by whole cell screening of a focused library against Mycobacterium tuberculosis. Herein, we describe the synthesis and structure activity relationship evaluation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502d1966bb4a545501a9cbae9bde47a3
https://doi.org/10.1016/j.bmcl.2013.06.043
https://doi.org/10.1016/j.bmcl.2013.06.043