Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rama Siman Tov"'
Publikováno v:
PLoS Pathogens, Vol 6, Iss 2, p e1000775 (2010)
Cytosine-5 methyltransferases of the Dnmt2 family function as DNA and tRNA methyltransferases. Insight into the role and biological significance of Dnmt2 is greatly hampered by a lack of knowledge about its protein interactions. In this report, we ad
Externí odkaz:
https://doaj.org/article/2e7f0901cf2e49a7b1298a5dfdf94a5d
Autor:
Ayala Tovy, Rivka Hertz, Rama Siman-Tov, Sylvie Syan, Daniela Faust, Nancy Guillen, Serge Ankri
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 8, p e1247 (2011)
The unicellular parasite, Entamoeba histolytica, is exposed to numerous adverse conditions, such as nutrient deprivation, during its life cycle stages in the human host. In the present study, we examined whether the parasite virulence could be influe
Externí odkaz:
https://doaj.org/article/1295e1803278421e836f29dbdc3a28a4
Publikováno v:
Cellular Microbiology. 14:58-70
Adaptation to environmental stress is a key process that allows the unicellular parasite Entamoeba histolytica to survive in its human host. We previously characterized EhMLBP as an essential protein for the growth and the virulence of the parasite.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::859df4cddc7bec36b17a3e5e4dcaf626
https://doi.org/10.1111/j.1462-5822.2011.01697.x
https://doi.org/10.1111/j.1462-5822.2011.01697.x
Publikováno v:
Molecular and Biochemical Parasitology. 166:117-125
EhMLBP is an essential Entamoeba histolytica protein that binds preferentially to methylated long interspersed nuclear elements and rDNA. In an effort to identify more EhMLBP DNA substrates, we developed an affinity-based technique in which the C-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1f5dc403ea2919405c7d51e4a208af
https://doi.org/10.1016/j.molbiopara.2009.03.002
https://doi.org/10.1016/j.molbiopara.2009.03.002
Publikováno v:
Molecular Microbiology. 69:55-66
Summary EhMLBP has been identified as a protein that specifically binds to methylated long interspersed element (LINE) retrotransposons and rDNA in Entamoeba histolytica. EhMLBP is unique to Entamoeba parasites, which makes this protein a possible dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4136718311a0134a9dc9fffb5ae685a9
https://doi.org/10.1111/j.1365-2958.2008.06258.x
https://doi.org/10.1111/j.1365-2958.2008.06258.x
Publikováno v:
Molecular and Biochemical Parasitology. 147:55-63
In this study, we have isolated by affinity chromatography, using anti-m5C antibody as a ligand, a DNA encoding reverse transcriptase of LINE retrotransposon (RT LINE) in both Entamoeba invadens and Entamoeba histolytica. RT LINE transcripts were det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0273d9cfd6578325eeb3377510053b3
https://doi.org/10.1016/j.molbiopara.2006.02.005
https://doi.org/10.1016/j.molbiopara.2006.02.005
Publikováno v:
FEBS Letters. 579:6395-6402
The protozoan parasite Entamoeba histolytica expresses a cytosine-5 DNA methyltransferase (Ehmeth) that belongs to the DNMT2 protein family. The biological function of members of this DNMT2 family is unknown. In the present study, the 5′ region of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bbd2e71a5e8ac3b2b4473314dedc8e2
https://doi.org/10.1016/j.febslet.2005.09.101
https://doi.org/10.1016/j.febslet.2005.09.101
Publikováno v:
Biochemical and Biophysical Research Communications. 322:465-469
The genome of Drosophila melanogaster contains methylated cytosines. Recent studies indicate that DNA methylation in the fruit fly depends on one DNA methyltransferase, dDNMT2. No obvious phenotype is associated with the downregulation of this DNA me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd046e1df2de5a4087112b36404bdd91
https://doi.org/10.1016/j.bbrc.2004.07.134
https://doi.org/10.1016/j.bbrc.2004.07.134
Publikováno v:
Molecular and Biochemical Parasitology. 133:153-162
Serine proteinase inhibitors (serpins) are irreversible suicide inhibitors of proteinases that regulate a wide range of biological processes, including pathogen evasion of the host defence system. We report the cloning and characterization of a gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3037b6e323fbb416f172b108b32e799a
https://doi.org/10.1016/j.molbiopara.2003.10.003
https://doi.org/10.1016/j.molbiopara.2003.10.003
Publikováno v:
Nucleic Acids Research. 32:287-297
The DNA methylation status of the protozoan parasite Entamoeba histolytica was heretofore unknown. In the present study, we developed a new technique, based on the affinity of methylated DNA to 5-methylcytosine antibodies, to identify methylated DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a92f1fc47e9df2f9fb60e02789d803bb
https://doi.org/10.1093/nar/gkh161
https://doi.org/10.1093/nar/gkh161