Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Rama Mukherjee"'
Publikováno v:
International Journal of Molecular Sciences, Vol 8, Iss 9, Pp 894-919 (2007)
Flavoprotein monoamine oxidase is located on the outer membrane ofmitochondria. It catalyzes oxidative deamination of monoamine neurotransmitters such asserotonin, norepinephrine and dopamine and hence is a target enzyme for antidepressantdrugs. MAO
Externí odkaz:
https://doaj.org/article/fab3a679f20343d7920a7716c17739d5
Autor:
Musarrat Husain Warsi, Rama Mukherjee, Akash Chaurasiya, Dinesh P Asati, Gaurav K. Jain, Ajeet Kumar Singh, Roop K. Khar, Manika Chaurasiya
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 35:2162-2174
To evaluate the bioavailability of exemestane (EXM) from self-micro emulsifying drug delivery systems (SMEDDS) and suspension formulations, a sensitive, specific, and rapid liquid chromatography-mass spectrometric method was developed and validated.
Autor:
Ajeet Kumar Singh, Rama Mukherjee, Dinesh P Asati, Akash Chaurasiya, Satish Chandra Upadhyay, Roop K. Khar, Farhan Jalees Ahmad
Publikováno v:
Advanced Science Letters. 11:43-52
Autor:
Dinesh P Asati, Gautam Mishra, Akash Chaurasiya, Roop K. Khar, Ajeet Kumar Singh, Anshumali Awasthi, Rama Mukherjee
Publikováno v:
AAPS PharmSciTech. 10:906-916
Limited aqueous solubility of exemestane leads to high variability in absorption after oral administration. To improve the solubility and bioavailability of exemestane, the self-microemulsifying drug delivery system (SMEDDS) was developed. SMEDDS com
Autor:
Dinesh P Asati, Gaurav K. Jain, Anshumali Awasthi, Rama Mukherjee, Roop K. Khar, Gautam Mishra, Akash Chaurasiya, Ajeet Kumar Singh
Publikováno v:
Talanta. 78:1310-1314
Bicalutamide is a non-steroidal antiandrogen and is an oral medication that is used for treating prostate cancer. To evaluate the bioavailability of bicalutamide from bicalutamide self-microemulsifying drug delivery systems (SMEDDS) and bicalutamide
Autor:
Anu T. Singh, Anand C. Burman, Sarjana Dutt, Rama Mukherjee, Gurvinder Singh, Praveen Rajendran, Kakali Datta, Vinod K. Sanna, Manu Jaggi, Sudhanand Prasad
Publikováno v:
Investigational New Drugs. 26:505-516
We have reported earlier a novel combination of four structurally designed synthetic neuropeptide analogs of vasoactive intestinal peptide (VIP), bombesin, substance P and somatostatin, code-named DRF 7295 which have anti-tumor efficacy for adenocarc
Autor:
Rajendran Praveen, Anu T. Singh, Anand C. Burman, Rajan Sharma, Rinku Ahuja, Manu Jaggi, Sudhanand Prasad, Archana Mathur, Sarjana Dutt, Rama Mukherjee, Neena Gupta
Publikováno v:
Investigational New Drugs. 26:489-504
A novel peptide combination consisting of four synthetic neuropeptide analogs of Vasoactive Intestinal Peptide (VIP), Bombesin, Substance P and Somatostatin has been found to have potent anticancer activity in vitro and in vivo. The receptors of thes
Autor:
Manupriya Vishnoi, Anu T. Singh, Manu Jaggi, Sanjay K. Srivastava, Rama Mukherjee, Nidhi Rani, Anand C. Burman, Alka Madan, S. K. Agarwal
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:6660-6664
Several 1,8-naphthyridine-3-carboxamide derivatives (8-23) were synthesized and tested for in vitro cytotoxicity against eight cancer cell lines and a normal cell line. Compound 12 exhibited high cytotoxicity (IC(50)=1.37microM) in HBL-100 (breast) c
Autor:
Manu Jaggi, Roop K. Khar, Rama Mukherjee, Manoj Kumar Singh, Sushama Talegaonkar, Gautam Mishra, Tripta Bansal
Publikováno v:
Journal of Chromatography B. 859:261-266
A simple, sensitive, specific and high-resolution reversed-phase liquid chromatographic method utilizing ultraviolet detection has been developed and validated for simultaneous determination of topotecan and four intestinal permeability markers (aten
Autor:
Manu Jaggi, Meera Venkatesh, Sudhanand Prasad, Rama Mukherjee, Aruna Korde, Archana Mukherjee, Ambikalmajan M.R. Pillai, Natesan Ramamoorthy, Kanchan Kothari, Archana Mathur
Publikováno v:
Applied Radiation and Isotopes. 65:382-386
Vasoactive intestinal peptide (VIP) receptors are expressed abundantly on many types of tumors and, hence, radiolabeled VIP analogues are being explored for tumor imaging and therapy. Here, we report synthesis of three VIP analogues and their radiola